Detailed information NTG0051112

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: SPAF_RS01755
• Genome accession: NC_017905
• Coordinates: 329431..330165 (+)
• Length: 244 a.a.
• NCBI ID: WP_041826204.1
• Uniprot ID: -
• Organism: Streptococcus parasanguinis FW213
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 324431..335165

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPAF_RS01730 (Spaf_0312)	-	325173..326027 (+)	855	WP_037617561.1	PTS system mannose/fructose/sorbose family transporter subunit IID	-
SPAF_RS01735 (Spaf_0313)	-	326129..326422 (+)	294	WP_003013750.1	hypothetical protein	-
SPAF_RS01740 (Spaf_0314)	groES	326552..326833 (+)	282	WP_024055367.1	co-chaperone GroES	-
SPAF_RS01745 (Spaf_0316)	groL	326855..328480 (+)	1626	WP_003004647.1	chaperonin GroEL	-
SPAF_RS01755 (Spaf_0317)	comE/blpR	329431..330165 (+)	735	WP_041826204.1	response regulator transcription factor	Regulator
SPAF_RS01760 (Spaf_0318)	-	330197..331483 (+)	1287	WP_041826205.1	GHKL domain-containing protein	-
SPAF_RS01765 (Spaf_0320)	-	331772..332452 (+)	681	WP_014712801.1	ABC transporter ATP-binding protein	-
SPAF_RS01770 (Spaf_0321)	-	332449..333156 (+)	708	WP_014712802.1	hypothetical protein	-
SPAF_RS01775 (Spaf_0322)	-	333575..334519 (-)	945	WP_014712803.1	LacI family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28074.29 Da
• Isoelectric Point: 6.3932

>NTDB_id=51112 SPAF_RS01755 WP_041826204.1 329431..330165(+) (comE/blpR) [Streptococcus parasanguinis FW213]
MLKIFVLEDEWIQQSRIEAVLQDLIRQKSLQCKAPEVFGKSSQLLDAITERGAHHLFFLDIEIKGEEKKGLEIAKEIRKK
DPHATIVFVTTHSEFMPITFQYKVAALDFIDKTLGEEEFKERISSAIDYTLEQAGTTIAQDAFTFESAMARVQVPFNKIL
YVETSPTIHKVILHTQEESLEFYASIADIEKADPRLYRCHRSFVVNPQNITKIDKEAKKAFFENGDNCLISRTKYRGLLE
ALKK

Nucleotide

• Length: 735 bp

>NTDB_id=51112 SPAF_RS01755 WP_041826204.1 329431..330165(+) (comE/blpR) [Streptococcus parasanguinis FW213]
TTGTTGAAAATTTTTGTGTTAGAAGATGAATGGATCCAACAATCGCGTATCGAAGCGGTCTTGCAGGATCTCATCCGTCA
AAAATCCTTGCAATGCAAAGCGCCAGAAGTGTTTGGGAAGTCAAGCCAATTGCTGGATGCTATCACAGAGAGAGGCGCCC
ATCACCTATTCTTTTTAGATATCGAGATTAAAGGTGAGGAGAAAAAGGGTCTAGAGATCGCAAAAGAGATTCGTAAGAAA
GACCCCCATGCGACCATTGTCTTTGTCACCACTCACTCTGAATTCATGCCCATTACCTTTCAGTACAAAGTAGCTGCCTT
GGATTTTATCGATAAAACGCTGGGTGAGGAAGAGTTCAAAGAGAGAATCAGCTCAGCCATCGACTATACCTTGGAGCAAG
CTGGGACCACGATTGCGCAAGATGCCTTTACGTTTGAGAGTGCGATGGCGCGTGTACAAGTTCCTTTTAATAAGATTTTG
TATGTTGAAACGTCTCCAACCATTCACAAGGTCATTTTACACACCCAGGAAGAGAGCTTGGAATTTTACGCTAGTATTGC
CGATATCGAAAAAGCAGATCCCCGCTTGTATCGGTGCCACCGCTCCTTTGTGGTGAATCCGCAAAATATTACGAAGATTG
ATAAAGAAGCCAAGAAAGCTTTTTTTGAAAATGGGGACAATTGCTTGATCTCACGGACCAAGTACAGAGGCTTACTGGAA
GCTTTGAAAAAATAG

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-242)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.812	97.951	0.537
comE/comE1	Streptococcus equinus JB1	45.679	99.59	0.455
comE/comE2	Streptococcus gordonii strain NCTC7865	40.244	100	0.406
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	40.244	100	0.406
comE/comE2	Streptococcus equinus JB1	38.462	100	0.389
comE	Streptococcus pneumoniae TIGR4	36.4	100	0.373
comE	Streptococcus mitis SK321	36.4	100	0.373
comE	Streptococcus mitis NCTC 12261	36.4	100	0.373
comE	Streptococcus infantis strain Atu-4	36.4	100	0.373
comE	Streptococcus pneumoniae Rx1	36.4	100	0.373
comE	Streptococcus pneumoniae D39	36.4	100	0.373
comE	Streptococcus pneumoniae R6	36.4	100	0.373