Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   Q7C_RS10670 Genome accession   NC_017856
Coordinates   2217112..2218353 (-) Length   413 a.a.
NCBI ID   WP_014704782.1    Uniprot ID   I1YKC0
Organism   Methylophaga frappieri     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2212112..2223353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7C_RS10640 (Q7C_2220) nadA 2212945..2214057 (+) 1113 WP_014704775.1 quinolinate synthase NadA -
  Q7C_RS10645 (Q7C_2221) - 2214072..2214257 (+) 186 WP_014704776.1 zinc-finger domain-containing protein -
  Q7C_RS10650 (Q7C_2222) mutT 2214254..2214694 (+) 441 WP_014704777.1 8-oxo-dGTP diphosphatase MutT -
  Q7C_RS13550 (Q7C_2223) yacG 2214651..2214845 (-) 195 WP_014704778.1 DNA gyrase inhibitor YacG -
  Q7C_RS10655 (Q7C_2224) zapD 2214845..2215621 (-) 777 WP_014704779.1 cell division protein ZapD -
  Q7C_RS10660 (Q7C_2225) coaE 2215628..2216239 (-) 612 WP_014704780.1 dephospho-CoA kinase -
  Q7C_RS10665 (Q7C_2226) pilD 2216243..2217112 (-) 870 WP_014704781.1 prepilin peptidase Machinery gene
  Q7C_RS10670 (Q7C_2227) pilC 2217112..2218353 (-) 1242 WP_014704782.1 type II secretion system F family protein Machinery gene
  Q7C_RS10675 (Q7C_2228) pilB 2218357..2220075 (-) 1719 WP_014704783.1 type IV-A pilus assembly ATPase PilB Machinery gene
  Q7C_RS13555 (Q7C_2229) lptM 2220218..2220346 (+) 129 WP_014704784.1 LPS translocon maturation chaperone LptM -
  Q7C_RS10680 (Q7C_2230) lysA 2220353..2221600 (+) 1248 WP_014704785.1 diaminopimelate decarboxylase -
  Q7C_RS10685 (Q7C_2231) dapF 2221604..2222452 (+) 849 WP_014704786.1 diaminopimelate epimerase -
  Q7C_RS10690 (Q7C_2232) - 2222428..2223132 (+) 705 WP_014704787.1 DUF484 family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45094.36 Da        Isoelectric Point: 9.8482

>NTDB_id=51040 Q7C_RS10670 WP_014704782.1 2217112..2218353(-) (pilC) [Methylophaga frappieri]
MAQAVAAKKKREPAPTLYLWQGTNKQGRRVKGQMTGEGVQAVRADLRRQGITPLKVRKKPKDLFAPRKPPIKPADIAIFS
RMLATMMSSGVPLMQSMQIIGEGHENASMQEMILSIKADVESGTSLAESLSKFPLHFNDLYVSLVNAGEQSGTLEALLHE
IATYQEKTEALKAKIRKALVYPAAIIVVAFIVTAILMIFVIPQFESLFTGFGADLPGLTKLVISISEVFQEKWWLIFGVL
IGTVVGFMMAKKRSRKVQHFLDRLTLKLPVIGEVMTKGAIARFSRTFSVMFKAGVPMVDAMTSVAGATGNIVYTDATLAM
RDDVATGTQLNKAMVDTELFPNMVIQMVAIGEESGSLDSMLAKVADFFEREVDDAVDNMTALLEPLIMAFLGVVVGTLVI
AMYLPIFKLGAVV

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=51040 Q7C_RS10670 WP_014704782.1 2217112..2218353(-) (pilC) [Methylophaga frappieri]
ATGGCGCAAGCGGTAGCAGCGAAGAAAAAACGAGAACCAGCGCCGACGCTTTATCTCTGGCAGGGCACCAACAAGCAAGG
GCGGCGGGTCAAAGGACAGATGACGGGAGAAGGTGTGCAAGCAGTTCGTGCCGATCTGCGCCGTCAGGGCATTACACCGT
TAAAAGTGCGCAAGAAACCCAAGGACTTGTTTGCGCCAAGAAAACCGCCTATCAAACCCGCCGACATTGCCATTTTCAGC
CGAATGCTGGCCACCATGATGTCTTCTGGCGTGCCGTTAATGCAATCCATGCAAATCATTGGCGAAGGCCATGAGAATGC
CTCCATGCAAGAGATGATTCTTAGCATTAAGGCAGATGTGGAATCAGGCACTAGTCTTGCCGAATCTTTATCAAAATTCC
CGCTTCACTTTAATGACCTCTACGTAAGCCTTGTCAATGCCGGTGAACAATCAGGCACGCTGGAAGCGTTGTTACACGAA
ATTGCCACCTATCAGGAAAAAACGGAAGCCCTTAAAGCCAAAATTCGTAAAGCATTGGTGTATCCGGCTGCCATTATCGT
CGTGGCTTTCATCGTGACCGCCATATTGATGATTTTTGTTATTCCTCAGTTTGAATCTTTGTTTACCGGATTTGGCGCTG
ATCTGCCTGGCCTGACCAAGTTGGTTATCTCGATTTCTGAGGTTTTCCAAGAGAAATGGTGGCTGATATTCGGGGTGCTG
ATTGGCACGGTTGTCGGCTTTATGATGGCCAAGAAACGCTCTCGCAAAGTACAACACTTTCTGGATCGCTTAACCCTCAA
ATTGCCGGTTATCGGCGAGGTGATGACCAAAGGTGCCATCGCCCGGTTTTCCCGGACATTTTCGGTCATGTTTAAAGCGG
GGGTGCCAATGGTAGATGCGATGACATCTGTAGCCGGTGCGACGGGCAATATAGTTTATACCGATGCCACACTCGCCATG
CGCGATGATGTGGCAACCGGAACACAGCTTAACAAAGCCATGGTTGATACCGAGTTATTTCCCAATATGGTGATTCAAAT
GGTCGCGATTGGTGAGGAATCGGGGTCTTTGGACTCGATGCTGGCGAAAGTTGCTGATTTCTTCGAGCGCGAAGTGGATG
ATGCCGTCGATAACATGACCGCCTTACTTGAACCACTCATTATGGCCTTTCTGGGTGTGGTTGTGGGTACGCTGGTTATT
GCCATGTATCTGCCGATATTCAAGCTTGGCGCGGTGGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(283-405)

Type II secretion system (T2SS), protein F (T2SSF)

(79-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I1YKC0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

54.703

97.821

0.535
  pilC Pseudomonas stutzeri DSM 10701

54.02

96.368

0.521
  pilC Acinetobacter baylyi ADP1

50.49

98.789

0.499
  pilC Acinetobacter baumannii D1279779

50.245

98.789

0.496
  pilG Neisseria gonorrhoeae MS11

42.298

99.031

0.419
  pilG Neisseria meningitidis 44/76-A

42.054

99.031

0.416
  pilC Vibrio cholerae strain A1552

42.929

95.884

0.412
  pilC Vibrio campbellii strain DS40M4

40.447

97.579

0.395
  pilC Thermus thermophilus HB27

37.89

100

0.383

Multiple sequence alignment