Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   MYY_RS10320 Genome accession   NC_017769
Coordinates   1942297..1942599 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae ST556     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1937297..1947599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYY_RS10290 (MYY_1962) rnpA 1937983..1938354 (-) 372 WP_000739246.1 ribonuclease P protein component -
  MYY_RS13570 - 1938371..1938502 (-) 132 WP_000768904.1 hypothetical protein -
  MYY_RS10295 (MYY_1963) - 1938503..1939693 (-) 1191 WP_000167766.1 acetate kinase -
  MYY_RS10300 (MYY_1964) comYH 1939744..1940697 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  MYY_RS10305 (MYY_1965) - 1940758..1941345 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  MYY_RS10310 (MYY_1966) comGG/cglG 1941482..1941895 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  MYY_RS10315 (MYY_1967) comGF/cglF 1941873..1942334 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  MYY_RS10320 (MYY_1968) comGE/cglE 1942297..1942599 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  MYY_RS10325 (MYY_1969) comGD/cglD 1942562..1942966 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  MYY_RS10330 (MYY_1970) comGC/cglC 1942959..1943285 (-) 327 WP_000738650.1 comG operon protein ComGC Machinery gene
  MYY_RS10335 (MYY_1971) comGB/cglB 1943287..1944303 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  MYY_RS10340 (MYY_1972) comGA/cglA/cilD 1944251..1945192 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  MYY_RS10345 (MYY_1973) - 1945268..1945633 (-) 366 WP_000286415.1 DUF1033 family protein -
  MYY_RS10350 (MYY_1974) - 1945784..1946842 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=50851 MYY_RS10320 WP_000413380.1 1942297..1942599(-) (comGE/cglE) [Streptococcus pneumoniae ST556]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=50851 MYY_RS10320 WP_000413380.1 1942297..1942599(-) (comGE/cglE) [Streptococcus pneumoniae ST556]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment