Detailed information NTG0050850

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: MYY_RS10315
• Genome accession: NC_017769
• Coordinates: 1941873..1942334 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250545.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae ST556
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1936873..1947334

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MYY_RS10285 (MYY_1961)	-	1937184..1938008 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
MYY_RS10290 (MYY_1962)	rnpA	1937983..1938354 (-)	372	WP_000739246.1	ribonuclease P protein component	-
MYY_RS13570	-	1938371..1938502 (-)	132	WP_000768904.1	hypothetical protein	-
MYY_RS10295 (MYY_1963)	-	1938503..1939693 (-)	1191	WP_000167766.1	acetate kinase	-
MYY_RS10300 (MYY_1964)	comYH	1939744..1940697 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
MYY_RS10305 (MYY_1965)	-	1940758..1941345 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
MYY_RS10310 (MYY_1966)	comGG/cglG	1941482..1941895 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
MYY_RS10315 (MYY_1967)	comGF/cglF	1941873..1942334 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
MYY_RS10320 (MYY_1968)	comGE/cglE	1942297..1942599 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
MYY_RS10325 (MYY_1969)	comGD/cglD	1942562..1942966 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
MYY_RS10330 (MYY_1970)	comGC/cglC	1942959..1943285 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
MYY_RS10335 (MYY_1971)	comGB/cglB	1943287..1944303 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
MYY_RS10340 (MYY_1972)	comGA/cglA/cilD	1944251..1945192 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
MYY_RS10345 (MYY_1973)	-	1945268..1945633 (-)	366	WP_000286415.1	DUF1033 family protein	-
MYY_RS10350 (MYY_1974)	-	1945784..1946842 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17855.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=50850 MYY_RS10315 WP_000250545.1 1941873..1942334(-) (comGF/cglF) [Streptococcus pneumoniae ST556]
MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RFYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=50850 MYY_RS10315 WP_000250545.1 1941873..1942334(-) (comGF/cglF) [Streptococcus pneumoniae ST556]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTGCT
CGTCATCAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTGGAAGGCAAT
CGTTTCTATATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae D39	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae R6	93.464	100	0.935
comGF/cglF	Streptococcus pneumoniae TIGR4	93.464	100	0.935
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915