Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   I2439_RS00730 Genome accession   NZ_CP065191
Coordinates   126267..127205 (+) Length   312 a.a.
NCBI ID   WP_196819764.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ46     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 120242..133134 126267..127205 within 0


Gene organization within MGE regions


Location: 120242..133134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2439_RS00705 (HIEAAJJG_00142) - 120242..121288 (+) 1047 WP_196820074.1 acyltransferase family protein -
  I2439_RS00710 (HIEAAJJG_00143) - 121349..121714 (+) 366 WP_037580641.1 DUF1033 family protein -
  I2439_RS00715 (HIEAAJJG_00144) - 122247..122750 (+) 504 WP_196819761.1 hypothetical protein -
  I2439_RS00720 (HIEAAJJG_00145) - 123434..125437 (+) 2004 WP_196819762.1 DUF1430 domain-containing protein -
  I2439_RS00725 (HIEAAJJG_00146) - 125439..126086 (+) 648 WP_196819763.1 ATP-binding cassette domain-containing protein -
  I2439_RS00730 (HIEAAJJG_00147) comGA/cglA 126267..127205 (+) 939 WP_196819764.1 competence type IV pilus ATPase ComGA Machinery gene
  I2439_RS00735 (HIEAAJJG_00148) comYB 127138..128172 (+) 1035 WP_231191948.1 competence type IV pilus assembly protein ComGB Machinery gene
  I2439_RS00740 (HIEAAJJG_00149) comGC 128173..128496 (+) 324 Protein_112 competence type IV pilus major pilin ComGC -
  I2439_RS00745 (HIEAAJJG_00150) comGD 128474..128899 (+) 426 WP_196819766.1 competence type IV pilus minor pilin ComGD -
  I2439_RS00750 (HIEAAJJG_00151) comGE 128856..129146 (+) 291 WP_196819767.1 competence type IV pilus minor pilin ComGE -
  I2439_RS00755 (HIEAAJJG_00152) comYF 129133..129567 (+) 435 WP_012677237.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2439_RS00760 (HIEAAJJG_00153) comGG 129545..129907 (+) 363 WP_012514785.1 competence type IV pilus minor pilin ComGG -
  I2439_RS00765 (HIEAAJJG_00154) comYH 129969..130922 (+) 954 WP_196819768.1 class I SAM-dependent methyltransferase Machinery gene
  I2439_RS00770 (HIEAAJJG_00155) - 130982..132181 (+) 1200 WP_165627047.1 acetate kinase -
  I2439_RS00775 (HIEAAJJG_00156) - 132544..133134 (-) 591 WP_196819769.1 hypothetical protein -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35383.58 Da        Isoelectric Point: 6.8990

>NTDB_id=507802 I2439_RS00730 WP_196819764.1 126267..127205(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDDTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQANRWNQQIDQLLAEGHLNSRQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=507802 I2439_RS00730 WP_196819764.1 126267..127205(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
ATGATTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCTGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGATAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGCGAAAAAAGACGCTGTCAGCTCGGTGCTTGTGACTACGAC
CTTGATGACACTAAGGTGTCTCTACGATTATCAGCTGTGGGTGATTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCTAGAGGCCTTT
ACCTCTTTTCTGGACCAGTCGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTCTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAACCGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATAGCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.742

99.359

0.673
  comYA Streptococcus mutans UA140

63.023

99.679

0.628
  comYA Streptococcus mutans UA159

63.023

99.679

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.613

99.359

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

61.29

99.359

0.609
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.679

0.522
  comGA Latilactobacillus sakei subsp. sakei 23K

40.767

91.987

0.375