Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   I2439_RS00735 Genome accession   NZ_CP065191
Coordinates   127138..128172 (+) Length   344 a.a.
NCBI ID   WP_231191948.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ46     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 120242..133134 127138..128172 within 0


Gene organization within MGE regions


Location: 120242..133134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2439_RS00705 (HIEAAJJG_00142) - 120242..121288 (+) 1047 WP_196820074.1 acyltransferase family protein -
  I2439_RS00710 (HIEAAJJG_00143) - 121349..121714 (+) 366 WP_037580641.1 DUF1033 family protein -
  I2439_RS00715 (HIEAAJJG_00144) - 122247..122750 (+) 504 WP_196819761.1 hypothetical protein -
  I2439_RS00720 (HIEAAJJG_00145) - 123434..125437 (+) 2004 WP_196819762.1 DUF1430 domain-containing protein -
  I2439_RS00725 (HIEAAJJG_00146) - 125439..126086 (+) 648 WP_196819763.1 ATP-binding cassette domain-containing protein -
  I2439_RS00730 (HIEAAJJG_00147) comGA/cglA 126267..127205 (+) 939 WP_196819764.1 competence type IV pilus ATPase ComGA Machinery gene
  I2439_RS00735 (HIEAAJJG_00148) comYB 127138..128172 (+) 1035 WP_231191948.1 competence type IV pilus assembly protein ComGB Machinery gene
  I2439_RS00740 (HIEAAJJG_00149) comGC 128173..128496 (+) 324 Protein_112 competence type IV pilus major pilin ComGC -
  I2439_RS00745 (HIEAAJJG_00150) comGD 128474..128899 (+) 426 WP_196819766.1 competence type IV pilus minor pilin ComGD -
  I2439_RS00750 (HIEAAJJG_00151) comGE 128856..129146 (+) 291 WP_196819767.1 competence type IV pilus minor pilin ComGE -
  I2439_RS00755 (HIEAAJJG_00152) comYF 129133..129567 (+) 435 WP_012677237.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2439_RS00760 (HIEAAJJG_00153) comGG 129545..129907 (+) 363 WP_012514785.1 competence type IV pilus minor pilin ComGG -
  I2439_RS00765 (HIEAAJJG_00154) comYH 129969..130922 (+) 954 WP_196819768.1 class I SAM-dependent methyltransferase Machinery gene
  I2439_RS00770 (HIEAAJJG_00155) - 130982..132181 (+) 1200 WP_165627047.1 acetate kinase -
  I2439_RS00775 (HIEAAJJG_00156) - 132544..133134 (-) 591 WP_196819769.1 hypothetical protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39466.70 Da        Isoelectric Point: 9.4503

>NTDB_id=507803 I2439_RS00735 WP_231191948.1 127138..128172(+) (comYB) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MISFLQRDISIAGRQGLKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYVTSMEASLLKGNGLADMLAAL
GYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKRKTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNALTDLLL
HLPHYFLGFCLLLLLLIGSFYLYARSCSRLRLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEMMSNEKS
QLMRELAKDIKQSLLAGQSFHQRVAAYPFFRKELSLMIEYGDIKSKLGRELDIYAQESWETFFSQLNRATQWIQPIIFLV
VAVVIVMIYAAILLPIYQHMGDVF

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=507803 I2439_RS00735 WP_231191948.1 127138..128172(+) (comYB) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
TTGATCAGCTTCTTGCAGAGGGACATCTCAATAGCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAAGCAGCAAGAAAA
GCTTATCCAATTGCTCTATAACCTATTGTCTAACGGCTTTAATTTGACAGAGGTCATTGCTTTTTTGAGAAAAAGCCAGC
TGCTACTGCCAGTCTATGTTACAAGTATGGAAGCAAGCCTATTAAAGGGCAACGGCCTTGCTGACATGCTAGCAGCCTTA
GGTTACTCTGATGCTGTTATGACACAAATTAATCTGGCAGATAAGCATGGCAATATCAAGCTAACCTTGGAAAAAATTCA
GGACTATCTGAGTCAATTTCGCCAAATCAAGCGAAAGACCATCGAGGCAGTCACTTATCCGATCATACTTTTGGGTTTTT
TAGTGGTTATCATGCTAGGCTTGCGGCATTACCTAATCCCTCAGCTAGAGAGTCAAAATGCCTTGACTGACTTGTTGCTT
CATTTGCCTCATTATTTCTTAGGTTTTTGTTTGCTTTTGCTGTTGCTAATTGGCTCTTTTTACCTATATGCCAGATCTTG
TAGTCGGCTAAGGCTATTTAGTCAACTGAGCTATTATCCTATCATTGGGTCTTTATTGCGGCAATATTTGACAGCCTACT
ATGCTAGAGAATGGGGCAACCTCATCGGACAAGGCTTAGAATTAATCACCATTTTAGAGATGATGTCAAACGAAAAGTCA
CAGCTCATGCGAGAGCTTGCCAAGGATATCAAGCAGAGTCTACTAGCTGGCCAATCCTTTCATCAAAGGGTTGCAGCTTA
TCCCTTTTTTAGAAAGGAGCTAAGCCTAATGATTGAATATGGCGACATCAAATCAAAGCTTGGTCGGGAGCTAGATATCT
ATGCCCAAGAAAGCTGGGAGACCTTTTTTAGTCAGCTCAATCGGGCAACACAATGGATCCAGCCAATTATTTTTTTAGTG
GTTGCTGTGGTTATTGTGATGATTTATGCTGCTATTTTATTACCAATTTATCAACATATGGGAGATGTTTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.867

98.547

0.541
  comYB Streptococcus mutans UA159

54.867

98.547

0.541
  comYB Streptococcus gordonii str. Challis substr. CH1

52.353

98.837

0.517
  comGB/cglB Streptococcus mitis NCTC 12261

48.81

97.674

0.477
  comGB/cglB Streptococcus mitis SK321

48.949

96.802

0.474
  comGB/cglB Streptococcus pneumoniae Rx1

48.649

96.802

0.471
  comGB/cglB Streptococcus pneumoniae D39

48.649

96.802

0.471
  comGB/cglB Streptococcus pneumoniae R6

48.649

96.802

0.471
  comGB/cglB Streptococcus pneumoniae TIGR4

48.649

96.802

0.471
  comGB Lactococcus lactis subsp. cremoris KW2

46.313

98.547

0.456