Detailed information NTG0506049

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: I6L86_RS06830
• Genome accession: NZ_CP077259
• Coordinates: 1421102..1421842 (+)
• Length: 246 a.a.
• NCBI ID: WP_001019941.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain FDAARGOS 1456
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1416102..1426842

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L86_RS06805 (I6L86_06805)	-	1416575..1417006 (+)	432	WP_025169729.1	hypothetical protein	-
I6L86_RS06810 (I6L86_06810)	-	1417009..1417398 (+)	390	Protein_1296	replication initiation factor domain-containing protein	-
I6L86_RS06815 (I6L86_06815)	-	1417561..1418031 (+)	471	WP_000447038.1	MarR family transcriptional regulator	-
I6L86_RS06820 (I6L86_06820)	-	1418031..1420307 (+)	2277	WP_000401876.1	ATP-binding cassette domain-containing protein	-
I6L86_RS06825 (I6L86_06825)	-	1420759..1421091 (+)	333	WP_000656278.1	LytTR family DNA-binding domain-containing protein	-
I6L86_RS06830 (I6L86_06830)	comE/blpR	1421102..1421842 (+)	741	WP_001019941.1	response regulator transcription factor	Regulator
I6L86_RS06835 (I6L86_06835)	-	1422071..1423216 (+)	1146	WP_000209246.1	low temperature requirement protein A	-
I6L86_RS06840 (I6L86_06840)	-	1423519..1423581 (+)	63	Protein_1302	conjugal transfer protein	-
I6L86_RS06845 (I6L86_06845)	-	1423906..1424589 (+)	684	WP_000492701.1	LexA family transcriptional regulator	-
I6L86_RS06850 (I6L86_06850)	-	1424592..1426007 (+)	1416	WP_000219659.1	Y-family DNA polymerase	-
I6L86_RS06855 (I6L86_06855)	-	1426004..1426369 (+)	366	WP_000981959.1	hypothetical protein	-
I6L86_RS06860 (I6L86_06860)	-	1426359..1426649 (+)	291	WP_001080187.1	DUF5960 family protein	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28746.12 Da
• Isoelectric Point: 5.9117

>NTDB_id=506049 I6L86_RS06830 WP_001019941.1 1421102..1421842(+) (comE/blpR) [Streptococcus mitis strain FDAARGOS 1456]
MNIFILEDNFLQQTRIENVVKKILVDNKIEYRHFEVYGKPQQLLEDISERGNHQLFLLDIEIKDDDKRGLDVAREIRKLD
SQAVIAFVTSHSEFMPVSFEYLVSAIDFIDKELPEPLFIKRIENVILSVSDNQGITVSEDSFIFTGSKAQIQVPFKDLLY
IETSTIAHKLTLYSKRDIVEFYGQLSDILKQEPRLFQCHRSFIVNPYNISLIDKENRLVHFQNGSSCIVSRLKIRPLMKV
IERLHD

Nucleotide

• Length: 741 bp

>NTDB_id=506049 I6L86_RS06830 WP_001019941.1 1421102..1421842(+) (comE/blpR) [Streptococcus mitis strain FDAARGOS 1456]
GTGAATATTTTTATACTAGAAGATAATTTTTTACAACAGACTAGAATTGAAAATGTTGTCAAAAAAATTTTGGTGGATAA
TAAGATTGAGTATAGGCATTTTGAGGTTTATGGAAAACCTCAACAGCTTTTAGAGGACATTTCAGAGAGAGGAAATCATC
AATTATTTTTACTTGATATTGAAATAAAAGATGATGACAAAAGAGGATTAGACGTTGCTAGAGAAATTAGAAAACTTGAT
TCTCAAGCAGTGATTGCTTTTGTAACATCTCATTCTGAGTTTATGCCTGTATCTTTTGAATATTTAGTATCAGCTATTGA
TTTCATTGATAAAGAATTACCTGAACCATTATTTATCAAACGAATTGAAAATGTTATTTTAAGTGTTAGCGATAATCAAG
GAATAACAGTATCTGAGGACTCTTTTATATTTACAGGATCCAAAGCTCAAATTCAAGTCCCTTTTAAAGATTTATTGTAT
ATTGAAACATCAACAATTGCTCATAAGTTGACTCTCTATTCAAAACGAGACATAGTTGAATTTTATGGACAATTGTCAGA
TATTCTTAAACAGGAACCACGTTTATTTCAATGTCATAGATCATTTATCGTAAATCCTTATAATATATCTTTAATTGATA
AAGAAAATCGGTTAGTTCATTTTCAGAACGGGTCCTCTTGTATTGTCTCTAGATTAAAAATTCGTCCACTTATGAAAGTT
ATCGAAAGACTTCATGACTAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (3-122)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	52.066	98.374	0.512
comE/comE1	Streptococcus equinus JB1	44.538	96.748	0.431
comE	Streptococcus mitis SK321	36.8	100	0.374
comE	Streptococcus mitis NCTC 12261	36.8	100	0.374
comE	Streptococcus pneumoniae Rx1	36.4	100	0.37
comE	Streptococcus pneumoniae R6	36.4	100	0.37
comE	Streptococcus pneumoniae D39	36.4	100	0.37
comE	Streptococcus pneumoniae TIGR4	36.4	100	0.37
comE	Streptococcus infantis strain Atu-4	36	100	0.366
comE/comE2	Streptococcus equinus JB1	36.885	99.187	0.366
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	36.437	100	0.366
comE/comE2	Streptococcus gordonii strain NCTC7865	36.437	100	0.366