Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   IF732_RS02340 Genome accession   NZ_CP063745
Coordinates   442919..443185 (+) Length   88 a.a.
NCBI ID   WP_000927911.1    Uniprot ID   A0A2S6DDE2
Organism   Staphylococcus aureus strain NAS_AN_212     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 437919..448185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF732_RS02310 (IF732_02310) - 438658..438861 (+) 204 WP_000087559.1 YqgQ family protein -
  IF732_RS02315 (IF732_02315) - 438858..439844 (+) 987 WP_000161315.1 ROK family glucokinase -
  IF732_RS02320 (IF732_02320) - 439844..440173 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  IF732_RS02325 (IF732_02325) - 440170..440793 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  IF732_RS02330 (IF732_02330) comGA 440845..441819 (+) 975 WP_031872164.1 competence type IV pilus ATPase ComGA Machinery gene
  IF732_RS02335 (IF732_02335) comGB 441791..442861 (+) 1071 WP_000776425.1 competence type IV pilus assembly protein ComGB Machinery gene
  IF732_RS02340 (IF732_02340) comGC 442919..443185 (+) 267 WP_000927911.1 competence type IV pilus major pilin ComGC Machinery gene
  IF732_RS02345 (IF732_02345) comGD 443163..443609 (+) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  IF732_RS02350 (IF732_02350) comGE 443596..443895 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  IF732_RS02355 (IF732_02355) comGF 443813..444310 (+) 498 WP_001825340.1 competence type IV pilus minor pilin ComGF Machinery gene
  IF732_RS02360 (IF732_02360) - 444407..444553 (+) 147 WP_001789879.1 hypothetical protein -
  IF732_RS02365 (IF732_02365) - 444543..445067 (+) 525 WP_001015120.1 shikimate kinase -
  IF732_RS02370 (IF732_02370) gcvT 445226..446317 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  IF732_RS02375 (IF732_02375) gcvPA 446337..447683 (+) 1347 WP_000019698.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 88 a.a.        Molecular weight: 9488.10 Da        Isoelectric Point: 7.1319

>NTDB_id=496421 IF732_RS02340 WP_000927911.1 442919..443185(+) (comGC) [Staphylococcus aureus strain NAS_AN_212]
MLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFIKEAQKTCKSGETITI
SNGEAVAN

Nucleotide


Download         Length: 267 bp        

>NTDB_id=496421 IF732_RS02340 WP_000927911.1 442919..443185(+) (comGC) [Staphylococcus aureus strain NAS_AN_212]
ATGCTATTAGTATTATTAATCATCAGTTTATTATTAATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACA
ATCAACAGGTTGTAATGCACAGGTAAAAATGGTTAATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCAT
CGTCTATTGAAGACTTAATTGCAGATGGTTTTATAAAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATT
AGTAATGGAGAAGCAGTTGCAAATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DDE2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

100

100

1
  comGC Staphylococcus aureus N315

100

100

1
  comYC Streptococcus gordonii str. Challis substr. CH1

41.573

100

0.42
  comGC/cglC Streptococcus pneumoniae TIGR4

43.529

96.591

0.42
  comGC/cglC Streptococcus mitis NCTC 12261

49.275

78.409

0.386
  comYC Streptococcus suis isolate S10

49.275

78.409

0.386
  comGC/cglC Streptococcus mitis SK321

49.275

78.409

0.386
  comGC/cglC Streptococcus pneumoniae Rx1

47.826

78.409

0.375
  comGC/cglC Streptococcus pneumoniae D39

47.826

78.409

0.375
  comGC/cglC Streptococcus pneumoniae R6

47.826

78.409

0.375