Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   INQ43_RS09930 Genome accession   NZ_CP063658
Coordinates   2187303..2188562 (+) Length   419 a.a.
NCBI ID   WP_194036332.1    Uniprot ID   A0A7S6ZWG5
Organism   Lysobacter sp. H23M47     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2182303..2193562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INQ43_RS09905 (INQ43_09905) - 2182597..2183040 (+) 444 WP_194036327.1 hypothetical protein -
  INQ43_RS09910 (INQ43_09910) nadS 2183151..2183441 (+) 291 WP_194036328.1 NadS family protein -
  INQ43_RS09915 (INQ43_09915) pilB 2183726..2185456 (+) 1731 WP_194036329.1 type IV-A pilus assembly ATPase PilB Machinery gene
  INQ43_RS09920 (INQ43_09920) - 2185553..2185855 (+) 303 WP_228062479.1 helix-turn-helix transcriptional regulator -
  INQ43_RS09925 (INQ43_09925) - 2185852..2187081 (+) 1230 WP_194036331.1 type II toxin-antitoxin system HipA family toxin -
  INQ43_RS09930 (INQ43_09930) pilC 2187303..2188562 (+) 1260 WP_194036332.1 type II secretion system F family protein Machinery gene
  INQ43_RS09935 (INQ43_09935) pilD 2188576..2189439 (+) 864 WP_193984256.1 A24 family peptidase Machinery gene
  INQ43_RS09940 (INQ43_09940) coaE 2189522..2190142 (+) 621 WP_194036333.1 dephospho-CoA kinase -
  INQ43_RS09945 (INQ43_09945) - 2190265..2191257 (-) 993 WP_194036334.1 Nudix family hydrolase -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45368.95 Da        Isoelectric Point: 10.2415

>NTDB_id=496170 INQ43_RS09930 WP_194036332.1 2187303..2188562(+) (pilC) [Lysobacter sp. H23M47]
MSVSRTAAKKPVVAPRRAEATPLFVWEGTDKRGITMKGEQTAKNANFVRAELRRMGITPKVVKIKPKPLFSAGKKVTPQD
IAVFARQVATMMKAGVPIVGALEIIASGNKNPRMQVLVNSIRSEVESGSSLSEALGQHPVQFDLLFRNLVAAGESAGVLE
TVLDTVATYKENTEALKGKIKKAMFYPAAVVAVALIVSAILLVFVVPMFEDVFASFGAELPAFTMLIIKLSRFMVAWWWL
ILIVAVATVVAFIMAKNRSVAFQFFLDRMILKVPVVGQIIHNSAIARFARTLAVTFRAGVPLVEGLDTVGGATGNIVYEK
AVHRIRDDVAVGYSVNMAMKQVNLFPHMVVQMVAIGEEAGALDTMLLKVAEFYEQEVDNAVDALSSLLEPMIMVFLGVVV
GGMVIAMYLPIFKLGAVVG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=496170 INQ43_RS09930 WP_194036332.1 2187303..2188562(+) (pilC) [Lysobacter sp. H23M47]
ATGTCTGTCAGCCGCACTGCCGCCAAGAAACCCGTCGTGGCGCCACGGCGCGCCGAAGCGACGCCGCTGTTCGTCTGGGA
AGGCACCGACAAGCGCGGCATCACCATGAAGGGCGAGCAGACCGCGAAGAACGCCAACTTCGTGCGCGCCGAGCTGCGCC
GCATGGGCATCACGCCCAAGGTCGTCAAGATCAAGCCCAAGCCGCTGTTCAGTGCCGGCAAGAAGGTGACGCCGCAGGAC
ATTGCGGTGTTCGCGCGACAGGTTGCCACGATGATGAAGGCCGGCGTGCCCATCGTCGGCGCGCTGGAGATCATCGCCAG
CGGCAACAAGAACCCCAGGATGCAGGTGCTGGTCAACTCGATCCGCTCCGAGGTCGAGAGCGGCTCTTCACTGAGCGAGG
CGCTGGGCCAGCATCCGGTCCAGTTCGACCTGCTGTTCCGCAACCTCGTGGCTGCCGGTGAGTCGGCCGGTGTGCTGGAA
ACGGTGCTGGATACGGTGGCGACCTACAAGGAAAACACCGAGGCGCTCAAGGGCAAGATCAAGAAGGCGATGTTCTACCC
AGCGGCCGTGGTTGCGGTCGCATTGATCGTCAGCGCGATCCTGCTGGTGTTCGTGGTGCCGATGTTCGAGGACGTGTTTG
CCAGCTTCGGCGCCGAGCTACCGGCGTTCACCATGCTGATCATCAAGCTGAGCCGGTTCATGGTGGCGTGGTGGTGGCTG
ATCCTGATCGTCGCGGTGGCTACCGTGGTGGCCTTCATCATGGCGAAGAACCGCTCGGTCGCGTTCCAGTTTTTCCTCGA
CCGTATGATCCTGAAGGTGCCGGTGGTCGGCCAGATCATCCACAACTCCGCCATCGCCCGCTTCGCTCGGACGTTGGCCG
TGACCTTTCGCGCCGGCGTGCCGTTGGTGGAAGGCCTGGATACGGTCGGCGGCGCCACCGGCAACATCGTCTACGAGAAG
GCTGTGCACCGCATCCGCGACGACGTGGCCGTGGGCTACTCGGTCAATATGGCGATGAAGCAGGTCAACCTGTTCCCGCA
CATGGTGGTGCAGATGGTGGCCATCGGCGAGGAAGCCGGCGCACTGGACACGATGCTGTTGAAGGTCGCGGAGTTCTACG
AGCAGGAAGTCGACAACGCCGTGGACGCGCTGTCCAGCCTGCTGGAGCCGATGATCATGGTGTTCCTGGGCGTGGTGGTG
GGCGGCATGGTGATTGCCATGTACCTGCCGATCTTCAAGCTTGGCGCCGTGGTGGGTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(84-207)

Type II secretion system (T2SS), protein F (T2SSF)

(288-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7S6ZWG5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.079

96.181

0.539
  pilC Legionella pneumophila strain ERS1305867

54.408

94.749

0.516
  pilC Acinetobacter baumannii D1279779

52.451

97.375

0.511
  pilC Acinetobacter baylyi ADP1

51.471

97.375

0.501
  pilG Neisseria gonorrhoeae MS11

45.074

96.897

0.437
  pilG Neisseria meningitidis 44/76-A

44.828

96.897

0.434
  pilC Vibrio campbellii strain DS40M4

41.855

95.227

0.399
  pilC Vibrio cholerae strain A1552

40.806

94.749

0.387
  pilC Thermus thermophilus HB27

37.438

96.897

0.363