Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   INV104_RS10315 Genome accession   NC_017591
Coordinates   1937319..1938260 (-) Length   313 a.a.
NCBI ID   WP_000249574.1    Uniprot ID   -
Organism   Streptococcus pneumoniae INV104     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1932319..1943260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INV104_RS12495 - 1932469..1933270 (+) 802 WP_128887635.1 IS5 family transposase -
  INV104_RS10280 - 1933421..1933897 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  INV104_RS10285 (INV104_17630) comGG/cglG 1934571..1934963 (-) 393 WP_001818966.1 competence type IV pilus minor pilin ComGG Machinery gene
  INV104_RS10290 (INV104_17640) comGF/cglF 1934941..1935402 (-) 462 WP_000250537.1 competence type IV pilus minor pilin ComGF Machinery gene
  INV104_RS10295 (INV104_17650) comGE/cglE 1935365..1935667 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  INV104_RS10300 (INV104_17660) comGD/cglD 1935630..1936034 (-) 405 WP_000588017.1 competence type IV pilus minor pilin ComGD Machinery gene
  INV104_RS10305 (INV104_17670) comGC/cglC 1936027..1936353 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  INV104_RS10310 (INV104_17680) comGB/cglB 1936355..1937371 (-) 1017 WP_001844019.1 competence type IV pilus assembly protein ComGB Machinery gene
  INV104_RS10315 (INV104_17690) comGA/cglA/cilD 1937319..1938260 (-) 942 WP_000249574.1 competence type IV pilus ATPase ComGA Machinery gene
  INV104_RS10320 (INV104_17700) - 1938336..1938701 (-) 366 WP_000286415.1 DUF1033 family protein -
  INV104_RS10325 (INV104_17710) - 1938852..1939910 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  INV104_RS10330 (INV104_17720) nagA 1940073..1941224 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  INV104_RS10335 (INV104_17730) - 1941377..1943194 (-) 1818 WP_001220841.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35581.48 Da        Isoelectric Point: 6.0083

>NTDB_id=49198 INV104_RS10315 WP_000249574.1 1937319..1938260(-) (comGA/cglA/cilD) [Streptococcus pneumoniae INV104]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRSDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=49198 INV104_RS10315 WP_000249574.1 1937319..1938260(-) (comGA/cglA/cilD) [Streptococcus pneumoniae INV104]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGCCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGATCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAAC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.722

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comYA Streptococcus gordonii str. Challis substr. CH1

77.419

99.042

0.767
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.487

99.681

0.543

Multiple sequence alignment