Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   H2514_RS01955 Genome accession   NZ_CP061847
Coordinates   466558..467820 (-) Length   420 a.a.
NCBI ID   WP_036191993.1    Uniprot ID   A0A0A0ESA5
Organism   Lysobacter sp. CW239     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 461558..472820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H2514_RS01940 (H2514_01940) mutT 463353..464396 (+) 1044 WP_036191987.1 8-oxo-dGTP diphosphatase MutT -
  H2514_RS01945 (H2514_01945) coaE 464858..465496 (-) 639 WP_036191989.1 dephospho-CoA kinase -
  H2514_RS01950 (H2514_01950) pilD 465635..466498 (-) 864 WP_036191991.1 A24 family peptidase Machinery gene
  H2514_RS01955 (H2514_01955) pilC 466558..467820 (-) 1263 WP_036191993.1 type II secretion system F family protein Machinery gene
  H2514_RS01960 (H2514_01960) pilB 468137..469864 (-) 1728 WP_036191997.1 type IV-A pilus assembly ATPase PilB Machinery gene
  H2514_RS01965 (H2514_01965) - 470143..470424 (+) 282 WP_036192000.1 type II toxin-antitoxin system RelE/ParE family toxin -
  H2514_RS01970 (H2514_01970) - 470434..470730 (+) 297 WP_036192002.1 HigA family addiction module antitoxin -
  H2514_RS01975 (H2514_01975) - 470776..471210 (-) 435 WP_224743902.1 DUF1643 domain-containing protein -
  H2514_RS13540 - 471233..471367 (-) 135 WP_255516726.1 hypothetical protein -
  H2514_RS13545 (H2514_01980) - 471556..472014 (-) 459 WP_036192005.1 pilin -
  H2514_RS01985 (H2514_01985) - 472450..472728 (+) 279 WP_036192015.1 type II toxin-antitoxin system RelE/ParE family toxin -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 45511.89 Da        Isoelectric Point: 10.3063

>NTDB_id=485074 H2514_RS01955 WP_036191993.1 466558..467820(-) (pilC) [Lysobacter sp. CW239]
MSVTRSAAKKPDVAVRRAEATPLFVWEGTDKRGVTMKGEQTAKNANFVRADLRRQGITPKVVKVKPKPLFGSAGKRVTPL
DIAIFARQIATMMKAGVPIVGALEIISSGNKNPKMQKLVNAIRADVESGSSLSEALGKHPVEFDELFRNLVRAGESAGVL
ETVLDTVATYKENTEALKGKIKKAMFYPAAVVAVALIVSAILLVFVVPMFEDVFASFGAELPAFTMLIIKLSRFMVAWWW
LLLLASVGAVVAFIMVRNRSIAFQYFLDRLILKVPVVGQIIHNSAISRFARTLAVTFKAGVPLVEGLTTVAGATGNIVYE
KAVNRVRDDVAVGYSVNMAMKQTNQFPHMVVQMVGIGEEAGALDTMLFKVAEFYEQEVNNAVDALSSLLEPMIMVFLGVV
VGGMVIAMYLPIFKLGAVVG

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=485074 H2514_RS01955 WP_036191993.1 466558..467820(-) (pilC) [Lysobacter sp. CW239]
ATGTCCGTTACCCGTTCTGCTGCCAAGAAGCCCGACGTCGCGGTGCGCCGCGCGGAAGCGACACCCTTGTTCGTCTGGGA
AGGCACCGACAAGCGCGGCGTCACCATGAAGGGCGAGCAGACCGCGAAGAACGCGAACTTCGTGCGCGCCGATCTGCGCC
GCCAGGGCATCACGCCCAAGGTGGTGAAGGTCAAGCCGAAGCCGTTGTTCGGCAGCGCCGGCAAGCGGGTCACGCCGCTG
GACATCGCGATCTTCGCGCGCCAGATCGCCACGATGATGAAGGCCGGTGTGCCGATCGTCGGTGCGCTGGAGATCATCTC
CAGCGGCAACAAGAATCCGAAGATGCAGAAGCTGGTCAATGCGATCCGCGCCGACGTGGAGAGCGGTTCGTCGCTGAGCG
AGGCGCTGGGCAAGCATCCGGTGGAGTTCGACGAGCTGTTCCGCAACCTGGTCAGGGCGGGTGAGTCCGCCGGTGTGCTG
GAGACGGTGCTCGACACCGTGGCGACCTACAAGGAAAACACCGAGGCGCTGAAGGGCAAGATCAAGAAGGCGATGTTCTA
CCCGGCCGCCGTGGTCGCGGTGGCGCTGATCGTCAGTGCGATCCTGCTGGTGTTCGTTGTGCCGATGTTCGAGGACGTGT
TCGCCAGCTTCGGCGCCGAGCTGCCGGCGTTCACCATGCTCATCATCAAGCTGAGCCGGTTCATGGTGGCGTGGTGGTGG
TTGCTGCTGCTCGCCAGCGTGGGCGCGGTGGTGGCCTTCATCATGGTCAGGAACCGCTCGATCGCGTTCCAGTACTTCCT
CGACCGCCTGATCCTGAAGGTGCCGGTGGTCGGCCAGATCATCCACAACTCGGCGATCTCGCGTTTTGCCCGCACGCTGG
CGGTGACCTTCAAGGCCGGCGTGCCGCTGGTCGAAGGCCTGACCACCGTGGCCGGCGCGACCGGCAACATCGTCTACGAG
AAGGCCGTCAACCGCGTGCGCGACGACGTCGCCGTCGGCTATTCGGTCAACATGGCGATGAAGCAGACCAACCAGTTCCC
GCACATGGTGGTGCAGATGGTCGGCATTGGCGAGGAGGCCGGCGCGCTGGACACGATGCTGTTCAAGGTCGCCGAGTTCT
ACGAGCAGGAGGTCAACAACGCGGTGGATGCGCTGTCGAGCCTGCTGGAGCCGATGATCATGGTGTTCCTGGGCGTGGTC
GTCGGCGGCATGGTGATCGCGATGTACCTGCCGATCTTCAAGCTCGGCGCGGTGGTGGGTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(85-208)

Type II secretion system (T2SS), protein F (T2SSF)

(289-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0A0ESA5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.188

96.19

0.54
  pilC Legionella pneumophila strain ERS1305867

54.156

94.524

0.512
  pilC Acinetobacter baumannii D1279779

52.206

97.143

0.507
  pilC Acinetobacter baylyi ADP1

51.471

97.143

0.5
  pilG Neisseria gonorrhoeae MS11

44.14

95.476

0.421
  pilG Neisseria meningitidis 44/76-A

43.89

95.476

0.419
  pilC Vibrio cholerae strain A1552

41.912

97.143

0.407
  pilC Vibrio campbellii strain DS40M4

42.065

94.524

0.398
  pilC Thermus thermophilus HB27

38.308

95.714

0.367