Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   J7T63_RS09050 Genome accession   NZ_CP072442
Coordinates   1725682..1726623 (-) Length   313 a.a.
NCBI ID   WP_071417491.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24726     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1720682..1731623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T63_RS09010 (J7T63_08935) - 1720759..1721952 (-) 1194 WP_372429425.1 acetate kinase -
  J7T63_RS09015 (J7T63_08940) comGH 1722008..1722964 (-) 957 WP_084831205.1 class I SAM-dependent methyltransferase Machinery gene
  J7T63_RS09020 (J7T63_08945) comGG 1723009..1723326 (-) 318 WP_082309152.1 competence type IV pilus minor pilin ComGG Machinery gene
  J7T63_RS09025 (J7T63_08950) comGF 1723304..1723741 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7T63_RS09030 (J7T63_08955) comGE 1723725..1724018 (-) 294 WP_082309154.1 competence type IV pilus minor pilin ComGE Machinery gene
  J7T63_RS09035 (J7T63_08960) comGD 1723990..1724418 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7T63_RS09040 (J7T63_08965) comGC 1724378..1724704 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7T63_RS09045 (J7T63_08970) comGB 1724701..1725800 (-) 1100 Protein_1725 competence type IV pilus assembly protein ComGB -
  J7T63_RS09050 (J7T63_08975) comGA/cglA/cilD 1725682..1726623 (-) 942 WP_071417491.1 competence type IV pilus ATPase ComGA Machinery gene
  J7T63_RS09055 (J7T63_08980) - 1726704..1727066 (-) 363 WP_014622006.1 DUF1033 family protein -
  J7T63_RS09060 (J7T63_08985) - 1727336..1728585 (+) 1250 Protein_1728 ISL3 family transposase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35411.58 Da        Isoelectric Point: 6.4142

>NTDB_id=483545 J7T63_RS09050 WP_071417491.1 1725682..1726623(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24726]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIHPIKDALDYRGLYLFAGPVGSGKTTLMHELVQEHFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLIGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=483545 J7T63_RS09050 WP_071417491.1 1725682..1726623(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24726]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCATCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCATTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAATAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comGA Streptococcus mutans UA159

64.217

100

0.642
  comGA Streptococcus mutans UA140

64.217

100

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comGA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.218

99.681

0.61
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

38.667

95.847

0.371