Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SPN034183_RS13415 Genome accession   NC_021028
Coordinates   493835..494560 (-) Length   241 a.a.
NCBI ID   WP_167750760.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN034183     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 488835..499560
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN034183_RS02650 (SPN034183_04880) - 488873..489211 (+) 339 WP_000682119.1 LytTR family DNA-binding domain-containing protein -
  SPN034183_RS02655 (SPN034183_04890) comE/blpR 489216..489953 (+) 738 WP_001219127.1 response regulator transcription factor Regulator
  SPN034183_RS02660 (SPN034183_04900) - 489967..491307 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SPN034183_RS02665 (SPN034183_04910) blpC 491349..491504 (-) 156 WP_000358813.1 quorum-sensing system pheromone BlpC -
  SPN034183_RS02670 (SPN034183_04920) - 491561..492922 (-) 1362 WP_015545695.1 bacteriocin secretion accessory protein -
  SPN034183_RS13405 comA/nlmT 492933..493436 (-) 504 WP_001808910.1 ATP-binding cassette domain-containing protein Regulator
  SPN034183_RS13410 comA/nlmT 493405..493845 (-) 441 WP_001808911.1 ATP-binding cassette domain-containing protein Regulator
  SPN034183_RS13415 comA/nlmT 493835..494560 (-) 726 WP_167750760.1 ABC transporter transmembrane domain-containing protein Regulator
  SPN034183_RS13420 (SPN034183_04940) comA/nlmT 494505..495092 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  SPN034183_RS02685 (SPN034183_04950) blpI 495374..495571 (+) 198 WP_001093258.1 bacteriocin-like peptide BlpI -
  SPN034183_RS02690 cipB 496038..496187 (+) 150 WP_001808912.1 bacteriocin-like peptide BlpO Regulator
  SPN034183_RS02695 (SPN034183_04990) - 496291..496410 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  SPN034183_RS02705 (SPN034183_05020) - 497196..497579 (+) 384 WP_000877381.1 hypothetical protein -
  SPN034183_RS02710 (SPN034183_05030) - 497631..498320 (+) 690 WP_000760526.1 CPBP family intramembrane glutamic endopeptidase -
  SPN034183_RS02715 (SPN034183_05040) blpZ 498362..498610 (+) 249 WP_000276499.1 immunity protein BlpZ -
  SPN034183_RS02720 (SPN034183_05050) - 498640..499251 (+) 612 WP_000394047.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 27490.04 Da        Isoelectric Point: 4.8430

>NTDB_id=48246 SPN034183_RS13415 WP_167750760.1 493835..494560(-) (comA/nlmT) [Streptococcus pneumoniae SPN034183]
MVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSF
FATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVEGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNHDV
MQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGNKISSEYPYPMVWRSISHV
E

Nucleotide


Download         Length: 726 bp        

>NTDB_id=48246 SPN034183_RS13415 WP_167750760.1 493835..494560(-) (comA/nlmT) [Streptococcus pneumoniae SPN034183]
TTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATC
AACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCC
TAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTC
TTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCAT
TCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGAGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTTC
TTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAGCCTTTCGAAAAAATGAACCATGATGTC
ATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGA
AGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTT
TACAAACGAGTTTAAAGCAGGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTC
GAGTAA

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(3-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

75.446

92.946

0.701
  comA Streptococcus mitis SK321

70

91.286

0.639
  comA Streptococcus pneumoniae Rx1

70

91.286

0.639
  comA Streptococcus pneumoniae D39

70

91.286

0.639
  comA Streptococcus pneumoniae R6

70

91.286

0.639
  comA Streptococcus mitis NCTC 12261

70

91.286

0.639
  comA Streptococcus pneumoniae TIGR4

69.545

91.286

0.635
  comA Streptococcus gordonii str. Challis substr. CH1

67.411

92.946

0.627

Multiple sequence alignment