Detailed information    

insolico Bioinformatically predicted

Overview


Name   comA/nlmT   Type   Regulator
Locus tag   SPN034183_RS13405 Genome accession   NC_021028
Coordinates   492933..493436 (-) Length   167 a.a.
NCBI ID   WP_001808910.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN034183     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context


Location: 487933..498436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN034183_RS02645 (SPN034183_04870) - 488268..488597 (-) 330 WP_000132570.1 hypothetical protein -
  SPN034183_RS02650 (SPN034183_04880) - 488873..489211 (+) 339 WP_000682119.1 LytTR family DNA-binding domain-containing protein -
  SPN034183_RS02655 (SPN034183_04890) comE/blpR 489216..489953 (+) 738 WP_001219127.1 response regulator transcription factor Regulator
  SPN034183_RS02660 (SPN034183_04900) - 489967..491307 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SPN034183_RS02665 (SPN034183_04910) blpC 491349..491504 (-) 156 WP_000358813.1 quorum-sensing system pheromone BlpC -
  SPN034183_RS02670 (SPN034183_04920) - 491561..492922 (-) 1362 WP_015545695.1 bacteriocin secretion accessory protein -
  SPN034183_RS13405 comA/nlmT 492933..493436 (-) 504 WP_001808910.1 ATP-binding cassette domain-containing protein Regulator
  SPN034183_RS13410 comA/nlmT 493405..493845 (-) 441 WP_001808911.1 ATP-binding cassette domain-containing protein Regulator
  SPN034183_RS13415 comA/nlmT 493835..494560 (-) 726 WP_167750760.1 ABC transporter transmembrane domain-containing protein Regulator
  SPN034183_RS13420 (SPN034183_04940) comA/nlmT 494505..495092 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  SPN034183_RS02685 (SPN034183_04950) blpI 495374..495571 (+) 198 WP_001093258.1 bacteriocin-like peptide BlpI -
  SPN034183_RS02690 cipB 496038..496187 (+) 150 WP_001808912.1 bacteriocin-like peptide BlpO Regulator
  SPN034183_RS02695 (SPN034183_04990) - 496291..496410 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  SPN034183_RS02705 (SPN034183_05020) - 497196..497579 (+) 384 WP_000877381.1 hypothetical protein -
  SPN034183_RS02710 (SPN034183_05030) - 497631..498320 (+) 690 WP_000760526.1 CPBP family intramembrane glutamic endopeptidase -

Sequence


Protein


Download         Length: 167 a.a.        Molecular weight: 18776.87 Da        Isoelectric Point: 8.1035

>NTDB_id=48244 SPN034183_RS13405 WP_001808910.1 492933..493436(-) (comA/nlmT) [Streptococcus pneumoniae SPN034183]
MIKKVLRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIA
LARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGIHQELMQAQGF
YHHLFNK

Nucleotide


Download         Length: 504 bp        

>NTDB_id=48244 SPN034183_RS13405 WP_001808910.1 492933..493436(-) (comA/nlmT) [Streptococcus pneumoniae SPN034183]
TTGATAAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAA
CTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACA
TTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCT
CTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAA
AAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAA
CCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTATCCACCAAGAGTTAATGCAAGCGCAAGGTTTC
TACCATCATCTATTCAATAAATAA

Domains


Predicted by InterProScan.

(4-99)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.951

98.204

0.707

  comA Streptococcus gordonii str. Challis substr. CH1

70.303

98.802

0.695

  comA Streptococcus mitis NCTC 12261

69.091

98.802

0.683

  comA Streptococcus pneumoniae Rx1

69.091

98.802

0.683

  comA Streptococcus pneumoniae D39

69.091

98.802

0.683

  comA Streptococcus pneumoniae R6

69.091

98.802

0.683

  comA Streptococcus mitis SK321

68.485

98.802

0.677

  comA Streptococcus pneumoniae TIGR4

68.485

98.802

0.677

  rcrQ Streptococcus mutans UA159

38.235

100

0.389


Multiple sequence alignment