Detailed information NTG0047928

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: NMBG2136_RS10005
• Genome accession: NC_017513
• Coordinates: 1911669..1912133 (-)
• Length: 154 a.a.
• NCBI ID: WP_011799029.1
• Uniprot ID: -
• Organism: Neisseria meningitidis G2136
• Function: DNA binding (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1904957..1922184	1911669..1912133	within	0

Gene organization within MGE regions

Location: 1904957..1922184

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBG2136_RS09960 (NMBG2136_1787)	-	1906345..1906590 (-)	246	WP_002226028.1	hypothetical protein	-
NMBG2136_RS09970 (NMBG2136_1788)	-	1906702..1907130 (+)	429	WP_002226027.1	CopD family protein	-
NMBG2136_RS09975 (NMBG2136_1789)	-	1907142..1907618 (+)	477	WP_002226026.1	CYTH domain-containing protein	-
NMBG2136_RS09980 (NMBG2136_1790)	-	1907968..1908456 (-)	489	WP_002226025.1	dihydrofolate reductase	-
NMBG2136_RS09985 (NMBG2136_1791)	aroG	1908524..1909579 (-)	1056	WP_002226024.1	3-deoxy-7-phosphoheptulonate synthase AroG	-
NMBG2136_RS14580	-	1909741..1909968 (-)	228	WP_153310284.1	hypothetical protein	-
NMBG2136_RS09990 (NMBG2136_1793)	-	1910194..1910502 (+)	309	WP_017629289.1	membrane protein	-
NMBG2136_RS14995 (NMBG2136_1794)	-	1910551..1910655 (-)	105	Protein_1851	IS1595 family transposase	-
NMBG2136_RS09995 (NMBG2136_1795)	-	1910759..1910965 (-)	207	WP_002220254.1	hypothetical protein	-
NMBG2136_RS10000 (NMBG2136_1796)	comP	1911132..1911581 (-)	450	WP_002221685.1	type IV pilin protein	Machinery gene
NMBG2136_RS10005 (NMBG2136_1797)	comE	1911669..1912133 (-)	465	WP_011799029.1	helix-hairpin-helix domain-containing protein	Machinery gene
NMBG2136_RS10040 (NMBG2136_1803)	-	1917932..1918738 (-)	807	WP_002221447.1	cytochrome C assembly family protein	-
NMBG2136_RS10045 (NMBG2136_1804)	ffh	1918958..1920328 (+)	1371	WP_002221448.1	signal recognition particle protein	-
NMBG2136_RS10050 (NMBG2136_1805)	dsbA2	1920659..1921354 (-)	696	WP_002215704.1	thiol:disulfide interchange protein DsbA/DsbL	Machinery gene
NMBG2136_RS10055 (NMBG2136_1806)	-	1921525..1922184 (-)	660	WP_002218694.1	NYN domain-containing protein	-

Sequence

Protein

• Length: 154 a.a.
• Molecular weight: 16519.75 Da
• Isoelectric Point: 10.9695

>NTDB_id=47928 NMBG2136_RS10005 WP_011799029.1 1911669..1912133(-) (comE) [Neisseria meningitidis G2136]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPAIPAAKK

Nucleotide

• Length: 465 bp

>NTDB_id=47928 NMBG2136_RS10005 WP_011799029.1 1911669..1912133(-) (comE) [Neisseria meningitidis G2136]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTATACCGGCCGCTAAAAAATAG

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (75-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734
comE	Neisseria gonorrhoeae MS11	92.623	79.221	0.734