Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   H7798_RS00590 Genome accession   NZ_CP060638
Coordinates   97607..97933 (+) Length   108 a.a.
NCBI ID   WP_011528161.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY141     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92607..102933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7798_RS00575 (H7798_00580) - 95239..95604 (+) 366 WP_030126461.1 DUF1033 family protein -
  H7798_RS00580 (H7798_00585) comYA 95697..96635 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  H7798_RS00585 (H7798_00590) comYB 96571..97605 (+) 1035 WP_227875237.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7798_RS00590 (H7798_00595) comYC 97607..97933 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  H7798_RS00595 (H7798_00600) comGD 97908..98336 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  H7798_RS00600 (H7798_00605) comGE 98293..98577 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  H7798_RS00605 (H7798_00610) comYF 98570..99004 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7798_RS00610 (H7798_00615) comGG 98988..99314 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  H7798_RS00615 (H7798_00620) comYH 99412..100365 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  H7798_RS00620 (H7798_00625) - 100424..101620 (+) 1197 WP_030126459.1 acetate kinase -
  H7798_RS00625 (H7798_00630) - 101806..102114 (+) 309 WP_030126458.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12362.29 Da        Isoelectric Point: 9.6949

>NTDB_id=476909 H7798_RS00590 WP_011528161.1 97607..97933(+) (comYC) [Streptococcus pyogenes strain TSPY141]
MINQWNNLRHKNLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=476909 H7798_RS00590 WP_011528161.1 97607..97933(+) (comYC) [Streptococcus pyogenes strain TSPY141]
ATGATTAATCAATGGAACAACTTACGACACAAGAATTTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
TATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comYC Streptococcus mutans UA159

52.475

93.519

0.491
  comYC Streptococcus mutans UA140

52.475

93.519

0.491
  comYC Streptococcus suis isolate S10

58.025

75

0.435