Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   M001_RS02120 Genome accession   NZ_CP059396
Coordinates   433935..435176 (-) Length   413 a.a.
NCBI ID   WP_005336136.1    Uniprot ID   A0A0T6QCE0
Organism   Aeromonas veronii Hm21     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 428935..440176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M001_RS02095 (M001_002095) mutT 430927..431331 (+) 405 WP_019444787.1 8-oxo-dGTP diphosphatase MutT -
  M001_RS02100 (M001_002100) yacG 431409..431603 (-) 195 WP_021231282.1 DNA gyrase inhibitor YacG -
  M001_RS02105 (M001_002105) zapD 431613..432335 (-) 723 WP_021231281.1 cell division protein ZapD -
  M001_RS02110 (M001_002110) coaE 432373..432987 (-) 615 WP_021231280.1 dephospho-CoA kinase -
  M001_RS02115 (M001_002115) pilD 433001..433873 (-) 873 WP_021231279.1 prepilin peptidase Machinery gene
  M001_RS02120 (M001_002120) pilC 433935..435176 (-) 1242 WP_005336136.1 type II secretion system F family protein Machinery gene
  M001_RS02125 (M001_002125) pilB 435417..437123 (-) 1707 WP_021231278.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  M001_RS02130 (M001_002130) - 437127..437591 (-) 465 WP_021231277.1 pilin -
  M001_RS02135 (M001_002135) nadC 437910..438770 (-) 861 WP_021231276.1 carboxylating nicotinate-nucleotide diphosphorylase -
  M001_RS02140 (M001_002140) - 438774..439244 (-) 471 WP_021231275.1 retropepsin-like aspartic protease family protein -
  M001_RS02145 (M001_002145) ampD 439375..439950 (+) 576 WP_021231274.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45427.55 Da        Isoelectric Point: 9.7221

>NTDB_id=469323 M001_RS02120 WP_005336136.1 433935..435176(-) (pilC) [Aeromonas veronii Hm21]
MATLTKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGDVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=469323 M001_RS02120 WP_005336136.1 433935..435176(-) (pilC) [Aeromonas veronii Hm21]
ATGGCAACCCTAACGAAAAAGAACAATGCCCCCAAGAAAGTCTTCGCCTTCCGCTGGCATGGGGTTAATCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTGCAGGCCGACAGCATCAACACCGTCAAGACCGAACTGCGCAAGCAGGGAGTCAACGTCACCA
AGGTAGCCAAGAAATCCCAGGGGCTCTTCTCCAAGGGCGGTGCCAAGATCAAGCCGATGGATATCGCCATCGTCTCACGC
CAGATCACCACCATGCTCTCCGCCGGCGTACCACTGGTGCAGAGCCTGCAGATCATCGCTCGCAGTCACGAGAAAGCCTC
GATGCGCGAGCTGATGGGGCAGATTGCCGCCGATGTGGAGACCGGCACCCCCATGTCGGAGGCGCTGCGTCGCCATCCTC
TCTATTTCGATGATCTCTACTGCGATCTGGTGGAAGCCGGTGAGCAATCCGGTGCACTGGAGACCATCTACGACCGTATC
GCCACTTACCGGGAAAAGTCGGAAGCGCTCAAGTCGAAGATCAAGAAGGCGATGTTCTACCCCACCATGGTCATTCTGGT
CGCCATCGTGGTCACCTCCATCCTGCTGCTGTTCGTCATTCCGCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCTGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACAGCC
CTTGGCATCTTCCTTTACGTGCGGGCCTGGCGGGCCTCCCAGAAGGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTAGTCGGGATGATCCTGCACAAGGCAGCGATGGCCCGCTTTGCCCGCACTCTGTCGACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCGCTGATTTCGGCGGCTGGAGCCTCCGGCAACTATGTCTATCGCACCGCTGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGTATGCAGATCAACGTTGCAATGCGCACCGTCGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGTGAAGAGTCCGGTGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATTGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGACGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T6QCE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

50.985

98.305

0.501
  pilC Vibrio cholerae strain A1552

46.883

97.094

0.455
  pilC Vibrio campbellii strain DS40M4

45.792

97.821

0.448
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

38

96.852

0.368