Detailed information NTG0453788

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: I6I02_RS07075
• Genome accession: NZ_CP066093
• Coordinates: 1569731..1570465 (+)
• Length: 244 a.a.
• NCBI ID: WP_198463333.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1564731..1575465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS07055 (I6I02_07055)	-	1565575..1567038 (+)	1464	WP_198463329.1	replication initiation protein	-
I6I02_RS07060 (I6I02_07060)	-	1567226..1568209 (+)	984	WP_198463330.1	tyrosine-type recombinase/integrase	-
I6I02_RS07065 (I6I02_07065)	-	1568424..1569233 (+)	810	WP_232621248.1	DNA/RNA non-specific endonuclease	-
I6I02_RS07070 (I6I02_07070)	-	1569327..1569503 (+)	177	Protein_1401	SH3 domain-containing protein	-
I6I02_RS07075 (I6I02_07075)	comE/blpR	1569731..1570465 (+)	735	WP_198463333.1	response regulator transcription factor	Regulator
I6I02_RS07080 (I6I02_07080)	-	1570462..1571781 (+)	1320	WP_198463334.1	sensor histidine kinase	-
I6I02_RS07085 (I6I02_07085)	-	1572057..1573898 (+)	1842	WP_198463335.1	SH3 domain-containing protein	-
I6I02_RS07090 (I6I02_07090)	-	1574029..1574682 (+)	654	WP_198463336.1	DUF6287 domain-containing protein	-
I6I02_RS07095 (I6I02_07095)	-	1575046..1575189 (+)	144	WP_198463337.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28534.91 Da
• Isoelectric Point: 6.3900

>NTDB_id=453788 I6I02_RS07075 WP_198463333.1 1569731..1570465(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_1045]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFRIENVKTVIQVPFHDIL
YLETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENVIKLDKSTGTVYFENGGVCYVSKLKLKKLLE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=453788 I6I02_RS07075 WP_198463333.1 1569731..1570465(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_1045]
ATGCTTAACATCTATGTTTTAGAAGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTAGGCGACTTCGAGGTTTTTGACAAACCCAATCAACTGTTAGAGTCTATTACCGAGCGAGGGTCTC
ATCAGCTCTTTTTCTTGGACATTCAAATTAAAGACGATACTAAAAAAGGTTTGGAGGTGGCTAAGCAGATTCGCAAGAAT
GATCCCTATGCCAATATTGTTTTCTTCACGACTCATTCAGAGTATCTTCCCTTAACTTTTCAATACCAATTGGCTGCTCT
GGACTTTATTGATAAGTCTTTGGAGGGGGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGATGCTTTTCGGATTGAGAATGTTAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTG
TACCTTGAGACCTCGGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
TCAAATTGAAAAGAGTGACCCTAGACTGTTTAAATGTCACAAATCTTTCCTTATCAACCCAGAAAATGTCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCGTTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (6-123)

• LytTr DNA-binding domain (LytTR) (151-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	50.41	100	0.504
comE/comE1	Streptococcus equinus JB1	47.699	97.951	0.467
comE/comE2	Streptococcus equinus JB1	41.736	99.18	0.414
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.272	99.59	0.381
comE/comE2	Streptococcus gordonii strain NCTC7865	38.272	99.59	0.381
comE	Streptococcus infantis strain Atu-4	37.344	98.77	0.369
comE	Streptococcus pneumoniae D39	36.929	98.77	0.365
comE	Streptococcus pneumoniae R6	36.929	98.77	0.365
comE	Streptococcus pneumoniae Rx1	36.929	98.77	0.365
comE	Streptococcus mitis SK321	36.929	98.77	0.365
comE	Streptococcus mitis NCTC 12261	36.929	98.77	0.365
comE	Streptococcus pneumoniae TIGR4	36.929	98.77	0.365