Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HQ912_RS24390 Genome accession   NZ_CP054128
Coordinates   5484045..5485262 (+) Length   405 a.a.
NCBI ID   WP_076386354.1    Uniprot ID   A0A1N7GWY4
Organism   Pseudomonas sp. MPDS     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5479045..5490262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ912_RS24370 (HQ912_24370) - 5480444..5480740 (+) 297 WP_047229856.1 DUF2845 domain-containing protein -
  HQ912_RS24375 (HQ912_24375) - 5481063..5481416 (-) 354 WP_047229857.1 BON domain-containing protein -
  HQ912_RS24380 (HQ912_24380) pilA 5481697..5482116 (-) 420 WP_047229858.1 pilin Machinery gene
  HQ912_RS24385 (HQ912_24385) pilB 5482342..5484042 (+) 1701 WP_047229859.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HQ912_RS24390 (HQ912_24390) pilC 5484045..5485262 (+) 1218 WP_076386354.1 type II secretion system F family protein Machinery gene
  HQ912_RS24395 (HQ912_24395) pilD 5485264..5486133 (+) 870 WP_047229861.1 prepilin peptidase Machinery gene
  HQ912_RS24400 (HQ912_24400) coaE 5486145..5486768 (+) 624 WP_047229862.1 dephospho-CoA kinase -
  HQ912_RS24405 (HQ912_24405) yacG 5486765..5486965 (+) 201 WP_047229863.1 DNA gyrase inhibitor YacG -
  HQ912_RS24410 (HQ912_24410) - 5486998..5487213 (-) 216 WP_076386357.1 hypothetical protein -
  HQ912_RS24415 (HQ912_24415) - 5487277..5487963 (-) 687 WP_047229865.1 energy-coupling factor ABC transporter permease -
  HQ912_RS24420 (HQ912_24420) - 5488109..5488735 (+) 627 WP_047229866.1 DUF1780 domain-containing protein -
  HQ912_RS24425 (HQ912_24425) - 5488732..5489259 (+) 528 WP_107322954.1 MOSC domain-containing protein -
  HQ912_RS24430 (HQ912_24430) - 5489312..5489485 (+) 174 WP_076386361.1 DUF3094 family protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44128.83 Da        Isoelectric Point: 10.1196

>NTDB_id=450929 HQ912_RS24390 WP_076386354.1 5484045..5485262(+) (pilC) [Pseudomonas sp. MPDS]
MAVKAIKTDVYTWEGKDRKGTKMTGELTGQSPALVKAQLRKQGINPGKVRKKSTSIFSKGKRIKPLDIALFTRQMATMLK
AGVPLLQAFDIIGEGFDNANMRKLVDEVKQEVAAGNSFAASLRKSPQYFDELYCNLVDAGEQAGALDTLLERVATYKEKS
EALKAKIKKAMTYPAAVVLVAAVVTGILLVKVVPQFESVFSGFGAQLPAFTVMVIGLSEFMQQWWWMLLGGAVAAFFGVK
HALKRSQGLRDWRDKWLLKLPLIGTLMYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFKRAVQRIRQDVSTGM
QLNFSMRASGIFPNMAIQMTAIGEESGALDDMLDKVASFYEAEVDNLVDNLTSLMEPFIMVVLGVVVGGLVVAMYLPIFQ
LGSAI

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=450929 HQ912_RS24390 WP_076386354.1 5484045..5485262(+) (pilC) [Pseudomonas sp. MPDS]
ATGGCGGTCAAGGCAATAAAAACCGACGTTTACACGTGGGAAGGCAAAGACCGCAAAGGCACGAAAATGACCGGCGAACT
GACTGGGCAGAGCCCGGCCCTGGTCAAGGCCCAGTTGCGCAAACAAGGCATCAACCCAGGCAAGGTTCGCAAGAAGTCCA
CCTCGATATTCAGCAAGGGCAAGCGTATCAAGCCATTGGATATCGCCCTGTTCACTCGTCAGATGGCGACCATGCTCAAG
GCCGGCGTGCCCTTGTTGCAGGCGTTCGACATCATTGGCGAAGGCTTCGACAACGCCAACATGCGCAAGCTGGTGGACGA
GGTGAAACAGGAAGTCGCCGCCGGCAACAGCTTCGCCGCGTCGTTGCGCAAGAGCCCGCAATACTTCGACGAACTGTACT
GCAACCTGGTGGACGCCGGTGAACAGGCCGGCGCCCTGGATACGCTGCTGGAGCGCGTCGCGACCTACAAGGAAAAAAGC
GAAGCCCTCAAGGCCAAGATCAAGAAGGCCATGACCTACCCGGCCGCTGTGGTGCTCGTCGCCGCCGTGGTCACGGGTAT
TCTGCTGGTCAAGGTGGTGCCGCAGTTCGAATCGGTATTCTCCGGGTTCGGCGCCCAACTGCCGGCCTTCACGGTGATGG
TCATCGGCCTGTCGGAGTTCATGCAGCAGTGGTGGTGGATGCTGCTGGGCGGCGCGGTGGCGGCGTTCTTCGGTGTCAAA
CATGCACTCAAGCGCTCCCAGGGCTTGCGTGACTGGCGCGATAAATGGCTGCTCAAACTGCCGCTGATCGGCACCCTGAT
GTACAAATCCGCCGTGGCCCGCTACGCCCGGACCCTGTCCACGACATTCGCGGCCGGCGTGCCGCTGGTGGAAGCCCTGG
ACTCGGTATCAGGCGCCACCGGTAACGTGGTGTTCAAACGCGCGGTACAACGCATCCGGCAGGATGTCTCGACCGGCATG
CAATTGAATTTTTCCATGCGTGCTTCAGGCATATTCCCGAACATGGCGATCCAGATGACCGCCATCGGCGAGGAGTCCGG
CGCGCTGGACGACATGCTCGACAAAGTGGCGAGCTTTTATGAAGCCGAGGTGGACAATCTGGTGGACAATCTCACCAGCC
TGATGGAACCGTTCATCATGGTGGTCCTGGGGGTGGTCGTCGGCGGCCTGGTGGTTGCCATGTACCTGCCCATCTTTCAA
CTCGGCTCTGCGATCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1N7GWY4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

74.074

100

0.741
  pilC Acinetobacter baylyi ADP1

59.601

99.012

0.59
  pilC Acinetobacter baumannii D1279779

58.088

100

0.585
  pilC Legionella pneumophila strain ERS1305867

55.25

98.765

0.546
  pilC Vibrio cholerae strain A1552

44.192

97.778

0.432
  pilC Vibrio campbellii strain DS40M4

43.687

97.778

0.427
  pilG Neisseria meningitidis 44/76-A

42.716

100

0.427
  pilG Neisseria gonorrhoeae MS11

42.786

99.259

0.425
  pilC Thermus thermophilus HB27

38.903

99.012

0.385