Detailed information NTG0449970

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: FOC73_RS07580
• Genome accession: NZ_CP053998
• Coordinates: 1559071..1559805 (+)
• Length: 244 a.a.
• NCBI ID: WP_002885563.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_771
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1554071..1564805

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC73_RS07565 (FOC73_07565)	-	1554969..1555664 (+)	696	WP_002885576.1	DUF6287 domain-containing protein	-
FOC73_RS07570 (FOC73_07570)	-	1555729..1556019 (+)	291	WP_002885564.1	hypothetical protein	-
FOC73_RS07575 (FOC73_07575)	-	1556305..1558860 (+)	2556	WP_002885546.1	SH3 domain-containing protein	-
FOC73_RS07580 (FOC73_07580)	comE/blpR	1559071..1559805 (+)	735	WP_002885563.1	response regulator transcription factor	Regulator
FOC73_RS07585 (FOC73_07585)	-	1559802..1561121 (+)	1320	WP_002885486.1	sensor histidine kinase	-
FOC73_RS07590 (FOC73_07590)	-	1561219..1561776 (+)	558	WP_002885505.1	hypothetical protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28554.90 Da
• Isoelectric Point: 6.3900

>NTDB_id=449970 FOC73_RS07580 WP_002885563.1 1559071..1559805(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_771]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESVTERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFRIENAKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENIIKLDKSTGTVYFENGGICYVSKLKLKKLLE
RISL

Nucleotide

• Length: 735 bp

>NTDB_id=449970 FOC73_RS07580 WP_002885563.1 1559071..1559805(+) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_771]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAACATTAAAGTAGGCGACTTTGAGGTTTTCGACAAACCCAATCAACTGTTAGAGTCTGTTACCGAGAGAGGGTCTC
ATCAGCTCTTTTTCCTGGACATTCAGATTAAAGACGATACTAAAAAAGGCTTGGAAGTGGCTAAGCAGATTCGCAAGAAT
GATCCCTATGCCAATATTGTTTTCTTCACGACCCATTCAGAGTATCTTCCCTTAACTTTTCAATACCAACTGGCAGCTCT
AGACTTTATTGATAAGTCTTTGGAGGGTGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGCTAAGACTGTTATTCAGGTTCCTTTTCATGATATCTTG
TACTTTGAGACGTCAGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
TCAAATTGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAATCCAGAAAATATCATCAAATTAG
ATAAAAGTACGGGGACAGTCTATTTTGAAAATGGTGGCATTTGCTATGTTTCAAAGTTGAAACTAAAGAAATTGCTTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-123)

• LytTr DNA-binding domain (LytTR) (151-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	50.82	100	0.508
comE/comE1	Streptococcus equinus JB1	48.117	97.951	0.471
comE/comE2	Streptococcus equinus JB1	42.562	99.18	0.422
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	39.095	99.59	0.389
comE/comE2	Streptococcus gordonii strain NCTC7865	39.095	99.59	0.389
comE	Streptococcus infantis strain Atu-4	37.344	98.77	0.369
comE	Streptococcus pneumoniae D39	36.929	98.77	0.365
comE	Streptococcus pneumoniae R6	36.929	98.77	0.365
comE	Streptococcus pneumoniae Rx1	36.929	98.77	0.365
comE	Streptococcus mitis SK321	36.929	98.77	0.365
comE	Streptococcus mitis NCTC 12261	36.929	98.77	0.365
comE	Streptococcus pneumoniae TIGR4	36.929	98.77	0.365