Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HQ395_RS04950 Genome accession   NZ_CP053885
Coordinates   1030919..1032160 (-) Length   413 a.a.
NCBI ID   WP_029302066.1    Uniprot ID   -
Organism   Aeromonas hydrophila strain 3019     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1025919..1037160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ395_RS04920 (HQ395_04920) - 1026758..1027942 (+) 1185 WP_029302061.1 tetratricopeptide repeat protein -
  HQ395_RS04925 (HQ395_04925) mutT 1027951..1028364 (+) 414 WP_174892455.1 8-oxo-dGTP diphosphatase MutT -
  HQ395_RS04930 (HQ395_04930) yacG 1028425..1028619 (-) 195 WP_029302063.1 DNA gyrase inhibitor YacG -
  HQ395_RS04935 (HQ395_04935) zapD 1028629..1029351 (-) 723 WP_016352172.1 cell division protein ZapD -
  HQ395_RS04940 (HQ395_04940) coaE 1029389..1030003 (-) 615 WP_029302064.1 dephospho-CoA kinase -
  HQ395_RS04945 (HQ395_04945) pilD 1030024..1030896 (-) 873 WP_029302065.1 A24 family peptidase Machinery gene
  HQ395_RS04950 (HQ395_04950) pilC 1030919..1032160 (-) 1242 WP_029302066.1 type II secretion system F family protein Machinery gene
  HQ395_RS04955 (HQ395_04955) pilB 1032276..1033982 (-) 1707 WP_029302067.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  HQ395_RS04960 (HQ395_04960) tapA 1033986..1034438 (-) 453 WP_041213796.1 type IVa pilus major pilin TapA -
  HQ395_RS04965 (HQ395_04965) nadC 1034761..1035618 (-) 858 WP_029302069.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HQ395_RS04970 (HQ395_04970) - 1035624..1036094 (-) 471 WP_029302070.1 retropepsin-like aspartic protease -
  HQ395_RS04975 (HQ395_04975) ampD 1036242..1036814 (+) 573 WP_029302071.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45418.50 Da        Isoelectric Point: 9.6551

>NTDB_id=448434 HQ395_RS04950 WP_029302066.1 1030919..1032160(-) (pilC) [Aeromonas hydrophila strain 3019]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIIVTSILLLFVIPQFEDIFKSFDAELPVFTQFVIGISRVMQNWWYVIFGGIA
LAIFLYVRAWRASQNVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=448434 HQ395_RS04950 WP_029302066.1 1030919..1032160(-) (pilC) [Aeromonas hydrophila strain 3019]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGGGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAAGGGCTCTTCTCCAAGGGCGGTGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGGCAGATTGCCGCCGATGTGGAGACCGGTACCCCCATGTCCGAGGCGCTGCGCCGCCATCCCC
GTCACTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAGTCCGGCGCGCTGGAGACCATCTACGATCGCATC
GCTACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATTCTGGT
GGCCATTATCGTTACCTCCATCCTGCTGCTGTTTGTCATTCCTCAGTTCGAGGACATCTTCAAGAGCTTCGACGCCGAGC
TGCCTGTCTTCACCCAGTTCGTCATCGGCATCTCACGCGTTATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAACGTCAAGGACAACACCGACAAGTTTATACTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCTGCCGGTA
TTCCACTGGTGGATGCCTTGGTTTCTGCGGCAGGCGCCTCCGGCAACTATGTCTACCGCACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTAGTACTGGGGGTTCTGGTCGGCGGCATGGTAGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.071

95.884

0.547
  pilC Acinetobacter baumannii D1279779

53.25

96.852

0.516
  pilC Legionella pneumophila strain ERS1305867

50.864

98.063

0.499
  pilC Acinetobacter baylyi ADP1

51.637

96.126

0.496
  pilC Vibrio cholerae strain A1552

47.487

96.368

0.458
  pilC Vibrio campbellii strain DS40M4

46.096

96.126

0.443
  pilG Neisseria gonorrhoeae MS11

39.506

98.063

0.387
  pilG Neisseria meningitidis 44/76-A

39.259

98.063

0.385
  pilC Thermus thermophilus HB27

37.5

96.852

0.363