Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   STT19_RS06665 Genome accession   NZ_CP065487
Coordinates   1292006..1292650 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST19     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1287006..1297650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT19_RS06640 (STT19_06670) - 1289108..1290106 (-) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -
  STT19_RS06645 (STT19_06675) trmD 1290108..1290827 (-) 720 WP_002951382.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  STT19_RS06650 (STT19_06680) rimM 1290817..1291335 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  STT19_RS06665 (STT19_06695) vraR 1292006..1292650 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  STT19_RS06670 (STT19_06700) - 1292640..1293650 (-) 1011 WP_011226288.1 sensor histidine kinase -
  STT19_RS06675 (STT19_06705) liaF 1293647..1294345 (-) 699 WP_023909818.1 cell wall-active antibiotics response protein LiaF -
  STT19_RS06680 - 1294600..1294767 (-) 168 WP_014608530.1 potassium channel family protein -
  STT19_RS06685 (STT19_06715) stkP/pknB 1295405..1297276 (-) 1872 WP_023909819.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=448435 STT19_RS06665 WP_002951384.1 1292006..1292650(-) (vraR) [Streptococcus thermophilus strain ST19]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=448435 STT19_RS06665 WP_002951384.1 1292006..1292650(-) (vraR) [Streptococcus thermophilus strain ST19]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379