Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HQ397_RS20300 Genome accession   NZ_CP053883
Coordinates   4397116..4398357 (-) Length   413 a.a.
NCBI ID   WP_252376355.1    Uniprot ID   -
Organism   Aeromonas hydrophila strain 4960     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4392116..4403357
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ397_RS22705 (HQ397_20190) - 4392957..4394140 (+) 1184 Protein_3930 tetratricopeptide repeat protein -
  HQ397_RS20275 (HQ397_20195) mutT 4394149..4394562 (+) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  HQ397_RS20280 (HQ397_20200) yacG 4394623..4394817 (-) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  HQ397_RS20285 (HQ397_20205) zapD 4394827..4395549 (-) 723 WP_016352172.1 cell division protein ZapD -
  HQ397_RS20290 (HQ397_20210) coaE 4395587..4396201 (-) 615 WP_016352171.1 dephospho-CoA kinase -
  HQ397_RS20295 (HQ397_20215) pilD 4396221..4397093 (-) 873 WP_252376354.1 A24 family peptidase Machinery gene
  HQ397_RS20300 (HQ397_20220) pilC 4397116..4398357 (-) 1242 WP_252376355.1 type II secretion system F family protein Machinery gene
  HQ397_RS20305 (HQ397_20225) pilB 4398473..4400179 (-) 1707 WP_029302067.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  HQ397_RS20310 (HQ397_20230) tapA 4400183..4400635 (-) 453 WP_252376356.1 type IVa pilus major pilin TapA -
  HQ397_RS20315 (HQ397_20235) nadC 4400958..4401815 (-) 858 WP_252376357.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HQ397_RS20320 (HQ397_20240) - 4401821..4402291 (-) 471 WP_024944772.1 retropepsin-like aspartic protease -
  HQ397_RS20325 (HQ397_20245) ampD 4402439..4403011 (+) 573 WP_252376358.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45452.60 Da        Isoelectric Point: 9.8637

>NTDB_id=448420 HQ397_RS20300 WP_252376355.1 4397116..4398357(-) (pilC) [Aeromonas hydrophila strain 4960]
MATLTQKQNVPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRSSQKVKDNTDKFILSIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=448420 HQ397_RS20300 WP_252376355.1 4397116..4398357(-) (pilC) [Aeromonas hydrophila strain 4960]
ATGGCAACGCTAACCCAGAAACAGAATGTCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGAGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAAGGCGGTGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCTGC
CATGCGTGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCTATGTCGGAGGCGCTGCGCCGCCATCCCC
GTCACTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAATCCGGCGCTCTGGAGACCATCTACGATCGTATC
GCCACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTCACCTCCATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGATATCTTCAAGAGTTTCGGCGCCGAGC
TGCCCATCTTCACCCAGTTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCTCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTATCAAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACGACCTTTTCCGCCGGTA
TCCCGCTGGTGGATGCCTTGGTCTCTGCGGCAGGTGCCTCCGGCAACTATGTCTACCGCACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
AATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTGGTGTTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

47.42

98.547

0.467
  pilC Vibrio campbellii strain DS40M4

46.154

97.579

0.45
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366