Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HC169_RS19255 Genome accession   NZ_CP050788
Coordinates   4129882..4131123 (+) Length   413 a.a.
NCBI ID   WP_106885656.1    Uniprot ID   A0AAP4J3C9
Organism   Aeromonas media strain FiBL-4359     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4124882..4136123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HC169_RS19230 (HC169_19205) ampD 4125304..4125876 (-) 573 WP_404839555.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  HC169_RS19235 (HC169_19210) - 4126013..4126483 (+) 471 WP_106885659.1 TIGR02281 family clan AA aspartic protease -
  HC169_RS19240 (HC169_19215) nadC 4126487..4127350 (+) 864 WP_394293767.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HC169_RS19245 (HC169_19220) - 4127663..4128037 (+) 375 WP_404839556.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  HC169_RS19250 (HC169_19225) pilB 4128045..4129751 (+) 1707 WP_404839557.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  HC169_RS19255 (HC169_19230) pilC 4129882..4131123 (+) 1242 WP_106885656.1 type II secretion system F family protein Machinery gene
  HC169_RS19260 (HC169_19235) pilD 4131204..4132076 (+) 873 WP_404839558.1 prepilin peptidase Machinery gene
  HC169_RS19265 (HC169_19240) coaE 4132095..4132709 (+) 615 WP_404839559.1 dephospho-CoA kinase -
  HC169_RS19270 (HC169_19245) zapD 4132747..4133469 (+) 723 WP_307765796.1 cell division protein ZapD -
  HC169_RS19275 (HC169_19250) yacG 4133482..4133676 (+) 195 WP_042053535.1 DNA gyrase inhibitor YacG -
  HC169_RS19280 (HC169_19255) mutT 4133751..4134155 (-) 405 WP_404839560.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45345.33 Da        Isoelectric Point: 9.9044

>NTDB_id=434739 HC169_RS19255 WP_106885656.1 4129882..4131123(+) (pilC) [Aeromonas media strain FiBL-4359]
MATLAQKQNAPKKVFSFRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQGQGMFSKGGARIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSDALRRHPRHFDALYCDLVEAGEQSGALETIYDRI
AIYREKSEALKSKIKKAMFYPAMVILVAIIVTSILLLFVIPQFEEIFKSFGAELPAFTRFIIAISRFMQDWWYAIFGGIA
LTVFLYVRAWRSSQKVRDNTDKFILSIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATLAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=434739 HC169_RS19255 WP_106885656.1 4129882..4131123(+) (pilC) [Aeromonas media strain FiBL-4359]
ATGGCTACATTAGCTCAAAAACAAAACGCACCAAAAAAGGTCTTCTCCTTCCGCTGGCACGGCGTCAATCGCAAGGGACA
AAAGGTTTCCGGTGAGTTGCAAGCCGACAGCATCACGACAGTCAAGGCGGAGCTGCGCAAGCAGGGCGTCAATGTCACCA
GGGTCAGCAAGCAGGGCCAGGGAATGTTTTCCAAGGGCGGCGCCAGGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCTGCCGGCGTGCCGCTGGTGCAGAGCCTGCAGATCATTGCCCGTGGCCATGAAAAGGCGGC
GGTGCGCGAGCTGATCGGCCAGATCGCCGCCGATGTGGAGACAGGCACCCCCCTGTCAGATGCGCTGCGCCGCCACCCCC
GCCACTTCGATGCCCTCTACTGTGACCTGGTGGAGGCGGGGGAGCAGTCAGGCGCGCTGGAAACCATCTACGACCGGATT
GCCATCTATCGCGAGAAGAGCGAGGCGCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCCGCCATGGTCATCCTGGT
CGCCATCATAGTGACCTCCATACTGTTGCTGTTCGTCATCCCCCAGTTCGAAGAGATCTTCAAGAGCTTCGGGGCCGAGC
TGCCCGCCTTCACCCGATTCATCATTGCCATCTCCCGCTTCATGCAGGATTGGTGGTACGCCATCTTCGGCGGCATAGCC
CTGACAGTATTCCTCTATGTGCGCGCCTGGCGCAGCTCCCAGAAGGTACGTGACAACACCGACAAGTTCATCCTCTCCAT
TCCAGTCGTTGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TTCCCCTGGTGGATGCCCTGGTCTCCGCTGCCGGGGCCTCGGGCAACTATGTCTATCGCACGGCTACCCTGGCCATTCGC
AACGAAGTCGTGGCTGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTGTTCCCCGACATGGTGATCCAGATGGT
GATGATAGGTGAAGAGTCTGGCGCCATCGATGACATGCTCTCCAAAGTCGCCGCCATCTTCGAGCAGGAGGTGGACGACA
TGGTCGATGGTCTCACCAGCCTGCTCGAGCCCATCATCATGGTGGTGCTGGGGGTGCTGGTCGGCGGCATGGTCGTCGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

55.303

95.884

0.53
  pilC Legionella pneumophila strain ERS1305867

51.605

98.063

0.506
  pilC Acinetobacter baumannii D1279779

51.87

97.094

0.504
  pilC Acinetobacter baylyi ADP1

50.882

96.126

0.489
  pilC Vibrio cholerae strain A1552

46.192

98.547

0.455
  pilC Vibrio campbellii strain DS40M4

44.802

97.821

0.438
  pilG Neisseria meningitidis 44/76-A

40.247

98.063

0.395
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilC Thermus thermophilus HB27

38

96.852

0.368