Detailed information NTG0414620

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: GU337_RS11305
• Genome accession: NZ_CP047614
• Coordinates: 2226664..2226984 (-)
• Length: 106 a.a.
• NCBI ID: WP_061774318.1
• Uniprot ID: A0A290PY35
• Organism: Lactococcus raffinolactis strain Lr_19_7
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2221664..2231984

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GU337_RS11265 (GU337_11205)	-	2222190..2222960 (-)	771	WP_244165990.1	metal ABC transporter ATP-binding protein	-
GU337_RS11270 (GU337_11210)	-	2222960..2223409 (-)	450	WP_096039675.1	zinc-dependent MarR family transcriptional regulator	-
GU337_RS11275 (GU337_11215)	-	2223485..2224333 (-)	849	WP_167838309.1	aminotransferase class IV	-
GU337_RS11280 (GU337_11220)	ispE	2224417..2225268 (-)	852	WP_061774322.1	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	-
GU337_RS11285 (GU337_11225)	comGG	2225273..2225557 (-)	285	WP_096039677.1	competence type IV pilus minor pilin ComGG	-
GU337_RS11290 (GU337_11230)	comGF	2225569..2226012 (-)	444	WP_244165991.1	competence type IV pilus minor pilin ComGF	-
GU337_RS11295 (GU337_11235)	comGE	2225987..2226292 (-)	306	WP_082785376.1	competence type IV pilus minor pilin ComGE	-
GU337_RS12445	comGD	2226264..2226749 (-)	486	WP_312186085.1	competence type IV pilus minor pilin ComGD	-
GU337_RS11305 (GU337_11245)	comYC	2226664..2226984 (-)	321	WP_061774318.1	competence type IV pilus major pilin ComGC	Machinery gene
GU337_RS11310 (GU337_11250)	comYB	2226993..2228078 (-)	1086	WP_310592697.1	competence type IV pilus assembly protein ComGB	Machinery gene
GU337_RS11315 (GU337_11255)	comGA/cglA/cilD	2227960..2228901 (-)	942	WP_061774317.1	competence type IV pilus ATPase ComGA	Machinery gene
GU337_RS11320 (GU337_11260)	-	2228964..2229251 (-)	288	WP_167840317.1	hypothetical protein	-
GU337_RS11325 (GU337_11265)	-	2229337..2230335 (+)	999	WP_024047037.1	IS5-like element IS1194 family transposase	-

Sequence

Protein

• Length: 106 a.a.
• Molecular weight: 11969.96 Da
• Isoelectric Point: 9.8991

>NTDB_id=414620 GU337_RS11305 WP_061774318.1 2226664..2226984(-) (comYC) [Lactococcus raffinolactis strain Lr_19_7]
MKKEDMKKKIVRAFTLVEMLVVLLVISVLILLFIPNLSKQKETVKNTGNGAVVKVVNSQAELYRLDHTDDVTLGKLVSNG
NITQKQADAYNEYYKKNTTESREIPS

Nucleotide

• Length: 321 bp

>NTDB_id=414620 GU337_RS11305 WP_061774318.1 2226664..2226984(-) (comYC) [Lactococcus raffinolactis strain Lr_19_7]
CTGAAGAAAGAAGATATGAAGAAAAAAATAGTACGTGCTTTTACTTTAGTAGAAATGCTAGTTGTTCTTCTTGTCATTAG
TGTCTTAATTTTATTGTTTATCCCCAATCTATCCAAACAAAAAGAGACTGTTAAGAATACAGGAAACGGCGCTGTTGTAA
AGGTAGTTAACTCGCAAGCGGAACTTTATAGATTAGACCATACTGATGATGTTACCTTAGGCAAGCTAGTCAGCAATGGC
AATATCACACAAAAACAGGCGGATGCTTATAATGAGTACTATAAGAAGAACACAACAGAATCACGTGAAATTCCAAGCTA
G

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-32)

3D structure

• AlphaFold DB: A0A290PY35

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	66.337	95.283	0.632
comYC	Streptococcus mutans UA159	61.538	98.113	0.604
comYC	Streptococcus mutans UA140	61.538	98.113	0.604
comGC/cglC	Streptococcus mitis SK321	63.636	93.396	0.594
comGC/cglC	Streptococcus mitis NCTC 12261	62.887	91.509	0.575
comGC/cglC	Streptococcus pneumoniae R6	60.606	93.396	0.566
comGC/cglC	Streptococcus pneumoniae D39	60.606	93.396	0.566
comGC/cglC	Streptococcus pneumoniae TIGR4	60.606	93.396	0.566
comGC/cglC	Streptococcus pneumoniae Rx1	60.606	93.396	0.566
comGC	Lactococcus lactis subsp. cremoris KW2	59.783	86.792	0.519
comYC	Streptococcus suis isolate S10	57.5	75.472	0.434