Detailed information NTG0041392

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: HMPREF0833_RS07210
• Genome accession: NC_015678
• Coordinates: 1582103..1582861 (-)
• Length: 252 a.a.
• NCBI ID: WP_003018434.1
• Uniprot ID: -
• Organism: Streptococcus parasanguinis ATCC 15912
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1577103..1587861

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0833_RS07190 (HMPREF0833_11468)	-	1577559..1579181 (+)	1623	WP_013904364.1	ATP-binding cassette domain-containing protein	-
HMPREF0833_RS07195 (HMPREF0833_11469)	-	1579234..1581801 (+)	2568	WP_013904365.1	YfhO family protein	-
HMPREF0833_RS07210 (HMPREF0833_11470)	comE/comE2	1582103..1582861 (-)	759	WP_003018434.1	response regulator transcription factor	Regulator
HMPREF0833_RS07215 (HMPREF0833_11471)	-	1582858..1584198 (-)	1341	WP_041818394.1	GHKL domain-containing protein	-
HMPREF0833_RS07225 (HMPREF0833_11472)	rlmH	1584662..1585141 (-)	480	WP_003009233.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
HMPREF0833_RS07230 (HMPREF0833_11473)	htrA	1585346..1586527 (+)	1182	WP_013904367.1	S1C family serine protease	Regulator
HMPREF0833_RS07235 (HMPREF0833_11474)	spo0J	1586599..1587360 (+)	762	WP_013904368.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 252 a.a.
• Molecular weight: 29604.16 Da
• Isoelectric Point: 5.4869

>NTDB_id=41392 HMPREF0833_RS07210 WP_003018434.1 1582103..1582861(-) (comE/comE2) [Streptococcus parasanguinis ATCC 15912]
MKIFLLEDELSQQIRVEKHIAEIAKELEIKLEVISTGKITEFENYIQHSEIHQLYFLDIHIQDNEYCGLEIAQKIREANP
YAIIVFITTKSEFASITYRYKVSALDFIDKNLNEDLFRLKIKECIEYLTTIQIGNDDLTDYFEYDFKDKKIKIPFKDILY
IETVGSAYKLNLVGKNFQKEIAGSLSDVLEKDVEERYFSPHQSFIVNRSMIIGMDKKKKQLLLKEGYSCPISRSNIKRVK
KLIEEQNLEFSA

Nucleotide

• Length: 759 bp

>NTDB_id=41392 HMPREF0833_RS07210 WP_003018434.1 1582103..1582861(-) (comE/comE2) [Streptococcus parasanguinis ATCC 15912]
ATGAAGATTTTTTTATTAGAAGATGAGCTCTCTCAACAGATACGGGTAGAAAAACATATTGCAGAAATTGCTAAGGAATT
AGAAATTAAACTTGAAGTGATTTCTACCGGTAAAATTACAGAATTTGAAAATTATATCCAGCATTCTGAGATCCACCAAT
TATATTTTCTAGATATTCACATCCAAGACAATGAGTATTGTGGGCTAGAAATTGCTCAAAAAATACGAGAAGCAAATCCT
TATGCCATTATTGTTTTTATTACTACAAAATCGGAATTTGCTTCTATTACCTATCGTTATAAAGTATCTGCCTTGGATTT
TATTGATAAAAATTTGAATGAAGATTTATTTAGATTAAAAATTAAGGAGTGTATTGAGTACTTGACAACTATTCAAATTG
GAAATGATGATTTGACAGATTATTTTGAGTATGATTTTAAAGATAAAAAAATTAAAATTCCATTTAAGGATATTCTTTAT
ATCGAAACGGTTGGTTCAGCTTATAAATTAAACTTAGTTGGGAAAAATTTTCAAAAAGAAATTGCAGGAAGTTTATCAGA
TGTCTTGGAGAAGGATGTGGAGGAGAGATATTTTAGTCCTCATCAATCTTTTATCGTAAATAGAAGTATGATCATTGGAA
TGGATAAGAAAAAGAAACAGCTGCTGTTGAAAGAAGGGTATTCTTGTCCAATTTCAAGAAGTAATATCAAACGTGTCAAA
AAATTAATTGAAGAGCAAAATTTAGAATTTAGTGCTTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (29-120)

• LytTr DNA-binding domain (LytTR) (149-243)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus gordonii strain NCTC7865	49.597	98.413	0.488
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	49.597	98.413	0.488
comE	Streptococcus pneumoniae Rx1	47.581	98.413	0.468
comE	Streptococcus pneumoniae D39	47.581	98.413	0.468
comE	Streptococcus pneumoniae R6	47.581	98.413	0.468
comE	Streptococcus pneumoniae TIGR4	47.581	98.413	0.468
comE	Streptococcus mitis NCTC 12261	47.581	98.413	0.468
comE	Streptococcus mitis SK321	47.581	98.413	0.468
comE	Streptococcus infantis strain Atu-4	46.371	98.413	0.456
comE/blpR	Streptococcus mutans UA159	38.866	98.016	0.381