Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   GQR50_RS02115 Genome accession   NZ_CP046954
Coordinates   452117..453358 (-) Length   413 a.a.
NCBI ID   WP_011707570.1    Uniprot ID   A0KPV8
Organism   Aeromonas hydrophila strain HX-3     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 447117..458358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQR50_RS02085 (GQR50_02085) - 447967..449141 (+) 1175 Protein_387 tetratricopeptide repeat protein -
  GQR50_RS02090 (GQR50_02090) mutT 449150..449563 (+) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  GQR50_RS02095 (GQR50_02095) yacG 449624..449818 (-) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  GQR50_RS02100 (GQR50_02100) zapD 449828..450550 (-) 723 WP_024945431.1 cell division protein ZapD -
  GQR50_RS02105 (GQR50_02105) coaE 450588..451202 (-) 615 WP_158196555.1 dephospho-CoA kinase -
  GQR50_RS02110 (GQR50_02110) pilD 451222..452094 (-) 873 WP_158196556.1 A24 family peptidase Machinery gene
  GQR50_RS02115 (GQR50_02115) pilC 452117..453358 (-) 1242 WP_011707570.1 type II secretion system F family protein Machinery gene
  GQR50_RS02120 (GQR50_02120) pilB 453474..455180 (-) 1707 WP_146061427.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  GQR50_RS02125 (GQR50_02125) - 455184..455618 (-) 435 WP_158196557.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  GQR50_RS02130 (GQR50_02130) nadC 455941..456798 (-) 858 WP_158196558.1 carboxylating nicotinate-nucleotide diphosphorylase -
  GQR50_RS02135 (GQR50_02135) - 456804..457274 (-) 471 WP_171279818.1 TIGR02281 family clan AA aspartic protease -
  GQR50_RS02140 (GQR50_02140) ampD 457422..457994 (+) 573 WP_158196560.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45422.58 Da        Isoelectric Point: 9.8637

>NTDB_id=409639 GQR50_RS02115 WP_011707570.1 452117..453358(-) (pilC) [Aeromonas hydrophila strain HX-3]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=409639 GQR50_RS02115 WP_011707570.1 452117..453358(-) (pilC) [Aeromonas hydrophila strain HX-3]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTGAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTACAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAAAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCACTGCGCCGCCATCCCC
GCCACTTTGACGATCTTTATTGCGATCTGGTGGAGGCTGGCGAACAGTCCGGCGCCCTGGAGACCATCTATGATCGCATC
GCCACCTATCGCGAGAAATCGGAAGCCCTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTTATCCTGGT
GGCCATTGTCGTTACCTCCATCCTGCTGCTGTTCGTCATTCCCCAGTTCGAGGACATTTTCAAGAGTTTCGGCGCCGAGC
TGCCCATCTTCACCCAGTTCGTTATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATATTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACTACCTTCTCCGCCGGTA
TTCCACTGGTGGATGCCTTGGTCTCTGCGGCAGGCGCCTCTGGCAACTATGTCTATCGCACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAACCTCTCATCATGGTGGTGCTGGGGGTACTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0KPV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366

Multiple sequence alignment