Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HZ322_RS04225 Genome accession   NZ_CP059049
Coordinates   865933..866562 (+) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis strain N8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 860933..871562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HZ322_RS04200 (HZ322_04200) - 861220..862419 (+) 1200 WP_012897536.1 FtsW/RodA/SpoVE family cell cycle protein -
  HZ322_RS04205 (HZ322_04205) - 862450..863748 (+) 1299 WP_017864383.1 LCP family protein -
  HZ322_RS04210 (HZ322_04210) rpsN 863846..864115 (+) 270 WP_010905608.1 30S ribosomal protein S14 -
  HZ322_RS04215 (HZ322_04215) liaF 864281..864910 (+) 630 WP_017864384.1 cell wall-active antibiotics response protein LiaF -
  HZ322_RS04220 (HZ322_04220) - 864907..865905 (+) 999 WP_012897540.1 sensor histidine kinase -
  HZ322_RS04225 (HZ322_04225) vraR 865933..866562 (+) 630 WP_003131402.1 response regulator transcription factor Regulator
  HZ322_RS04230 (HZ322_04230) - 866633..867439 (+) 807 WP_017864385.1 Cof-type HAD-IIB family hydrolase -
  HZ322_RS04235 (HZ322_04235) - 867542..868132 (+) 591 WP_012897543.1 peptidylprolyl isomerase -
  HZ322_RS04240 (HZ322_04240) - 868134..868565 (+) 432 WP_003131405.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  HZ322_RS04245 (HZ322_04245) - 868562..869167 (+) 606 WP_003131406.1 TVP38/TMEM64 family protein -
  HZ322_RS04250 (HZ322_04250) - 869389..870633 (+) 1245 WP_017864388.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=408427 HZ322_RS04225 WP_003131402.1 865933..866562(+) (vraR) [Lactococcus lactis strain N8]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=408427 HZ322_RS04225 WP_003131402.1 865933..866562(+) (vraR) [Lactococcus lactis strain N8]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGATTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTGATGGATCGACTTGATGGAATTGGAGCAACTCAAAAGATTTTAGCCAAAAATCCAGAACGAAAAATT
TTAATTCTAACCAGTTTTATTGATGACGAAAAAGTTTTTCCAGCTTTAGCTGCTGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCCGCTGATATTGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGATGAACTTTTTATCAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTGTCAGACCGAACTCAAGCAACAATTTATGCCATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416

Multiple sequence alignment