Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   GOM48_RS00930 Genome accession   NZ_CP046523
Coordinates   183116..184132 (+) Length   338 a.a.
NCBI ID   WP_235097794.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 178116..189132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS00910 (GOM48_00895) - 178542..180359 (+) 1818 WP_084946820.1 acyltransferase family protein -
  GOM48_RS00915 (GOM48_00900) nagA 180500..181651 (+) 1152 WP_084945412.1 N-acetylglucosamine-6-phosphate deacetylase -
  GOM48_RS00920 (GOM48_00905) - 181800..182165 (+) 366 WP_000286399.1 DUF1033 family protein -
  GOM48_RS00925 (GOM48_00910) comGA/cglA/cilD 182227..183168 (+) 942 WP_235097792.1 competence type IV pilus ATPase ComGA Machinery gene
  GOM48_RS00930 (GOM48_00915) comGB/cglB 183116..184132 (+) 1017 WP_235097794.1 competence type IV pilus assembly protein ComGB Machinery gene
  GOM48_RS00935 (GOM48_00920) comGC/cglC 184134..184457 (+) 324 WP_235097796.1 competence type IV pilus major pilin ComGC Machinery gene
  GOM48_RS00940 (GOM48_00925) comGD/cglD 184420..184854 (+) 435 WP_235097798.1 competence type IV pilus minor pilin ComGD Machinery gene
  GOM48_RS00945 (GOM48_00930) comGE/cglE 184817..185119 (+) 303 WP_235097800.1 competence type IV pilus minor pilin ComGE Machinery gene
  GOM48_RS00950 (GOM48_00935) comGF/cglF 185082..185543 (+) 462 WP_002875275.1 competence type IV pilus minor pilin ComGF Machinery gene
  GOM48_RS00955 (GOM48_00940) comGG/cglG 185521..185934 (+) 414 WP_235097802.1 competence type IV pilus minor pilin ComGG Machinery gene
  GOM48_RS00960 (GOM48_00945) - 185967..186557 (+) 591 WP_235097805.1 class I SAM-dependent methyltransferase -
  GOM48_RS00965 (GOM48_00950) comYH 186616..187569 (+) 954 WP_235097806.1 class I SAM-dependent methyltransferase Machinery gene
  GOM48_RS00970 (GOM48_00955) - 187619..188809 (+) 1191 WP_235097808.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38499.60 Da        Isoelectric Point: 9.6792

>NTDB_id=404888 GOM48_RS00930 WP_235097794.1 183116..184132(+) (comGB/cglB) [Streptococcus oralis strain SOD]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVAQMHQGLAQGKSFSEMMNSLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLSKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMVSQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGREFSQTIGTYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEVFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=404888 GOM48_RS00930 WP_235097794.1 183116..184132(+) (comGB/cglB) [Streptococcus oralis strain SOD]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACTTTGTTTAA
CAACCTCTTCTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTCTTGGGAAGAAGTGCCCTGCTAGAAAAGGACTATG
TGGCCCAGATGCACCAAGGCTTGGCTCAGGGGAAATCATTCTCAGAAATGATGAACAGCTTGGGCTTTTCAAGTGCTATT
GTGACCCAGTTATCTCTAGCTGAAGTGCATGGAAATCTTCACCTGAGTCTGGGGAAGATAGAAGAATATCTGGATAATTT
GTCCAAGGTCAAGAAGAAGTTAATCGAAGTGGCGACCTATCCCCTGATTTTGCTAGGATTTCTCCTGCTAATCATGCTGG
GATTGAGAAACTATCTACTCCCCCAACTGGACAGTAGCAATATCGCCACCCAAATCATTGGCAATCTGCCACAAATTTTT
CTGGGACTAGTGTTGGTTTGCTCTCTGTCTCTACTTTTAGCTCTCACTTTTTACAAAAGAAGTTCCAAGATGCGGGTTTT
CTCGATGTTAGCACGGATTCCCTTTCTAGGAATCTTTGTCCAGACCTATCTGACAGCCTATTACGCGCGTGAATGGGGCA
ATATGGTTTCACAGGGAATGGAGCTGACGCAGATTTTTCAGATCATGCAGGAACAAGGTTCTCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAGACTATAGGAACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGAGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGTCTTTTTTACCCGAGTTAATCGTACCATGAATCTGGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

92.604

100

0.926
  comGB/cglB Streptococcus mitis NCTC 12261

92.308

100

0.923
  comGB/cglB Streptococcus pneumoniae Rx1

90.533

100

0.905
  comGB/cglB Streptococcus pneumoniae D39

90.533

100

0.905
  comGB/cglB Streptococcus pneumoniae R6

90.533

100

0.905
  comGB/cglB Streptococcus pneumoniae TIGR4

90.533

100

0.905
  comYB Streptococcus gordonii str. Challis substr. CH1

73.214

99.408

0.728
  comYB Streptococcus mutans UA140

58.934

94.379

0.556
  comYB Streptococcus mutans UA159

58.934

94.379

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

51.479

100

0.515

Multiple sequence alignment