Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbB/cilA   Type   Machinery gene
Locus tag   GL184_RS01770 Genome accession   NZ_CP046356
Coordinates   331055..331450 (+) Length   131 a.a.
NCBI ID   WP_000282467.1    Uniprot ID   A0A098Z0L0
Organism   Streptococcus pneumoniae strain 521     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 322925..334971 331055..331450 within 0


Gene organization within MGE regions


Location: 322925..334971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL184_RS01695 (GL184_01720) - 322925..323641 (+) 717 WP_000532876.1 YebC/PmpR family DNA-binding transcriptional regulator -
  GL184_RS01700 (GL184_01725) - 323765..324236 (+) 472 Protein_306 MarR family winged helix-turn-helix transcriptional regulator -
  GL184_RS01705 (GL184_01730) - 324253..325074 (+) 822 Protein_307 ABC transporter permease -
  GL184_RS01710 (GL184_01735) - 325129..326112 (+) 984 Protein_308 ATP-binding cassette domain-containing protein -
  GL184_RS01720 (GL184_01745) - 326178..326540 (+) 363 WP_000078805.1 DUF2200 domain-containing protein -
  GL184_RS01725 (GL184_01750) - 326537..327040 (+) 504 WP_000800947.1 phosphatase PAP2 family protein -
  GL184_RS01730 (GL184_01755) - 327154..327600 (+) 447 WP_000776589.1 LytTR family DNA-binding domain-containing protein -
  GL184_RS01735 (GL184_01760) - 327606..328280 (+) 675 WP_024477660.1 LiaF transmembrane domain-containing protein -
  GL184_RS01740 (GL184_01765) - 328441..328632 (+) 192 WP_000291826.1 cell wall-binding protein -
  GL184_RS11000 - 328689..328835 (-) 147 WP_000692801.1 hypothetical protein -
  GL184_RS01750 (GL184_01770) - 328929..329228 (+) 300 WP_001818001.1 DUF4651 domain-containing protein -
  GL184_RS01755 (GL184_01775) - 329225..329542 (+) 318 WP_000615775.1 thioredoxin family protein -
  GL184_RS01760 (GL184_01780) ytpR 329558..330184 (+) 627 WP_024477659.1 YtpR family tRNA-binding protein -
  GL184_RS01765 (GL184_01785) - 330217..330978 (+) 762 WP_001107755.1 SDR family NAD(P)-dependent oxidoreductase -
  GL184_RS01770 (GL184_01790) ssbB/cilA 331055..331450 (+) 396 WP_000282467.1 single-stranded DNA-binding protein Machinery gene
  GL184_RS01775 (GL184_01795) groES 331720..332004 (+) 285 WP_000917330.1 co-chaperone GroES -
  GL184_RS01780 (GL184_01800) groL 332020..333642 (+) 1623 WP_000031585.1 chaperonin GroEL -
  GL184_RS01785 (GL184_01805) - 333742..334971 (-) 1230 WP_000436406.1 ISL3 family transposase -

Sequence


Protein


Download         Length: 131 a.a.        Molecular weight: 14925.89 Da        Isoelectric Point: 5.9409

>NTDB_id=403102 GL184_RS01770 WP_000282467.1 331055..331450(+) (ssbB/cilA) [Streptococcus pneumoniae strain 521]
MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVNMVLWGRLAETLASYATKGSLISVDGELRTR
RFEKNGQMNYVTEVLVTGFQLLESRAQRAMRENNAGQDLADLVLEEEELPF

Nucleotide


Download         Length: 396 bp        

>NTDB_id=403102 GL184_RS01770 WP_000282467.1 331055..331450(+) (ssbB/cilA) [Streptococcus pneumoniae strain 521]
ATGTATAATAAAGTTATCATGATTGGGCGTTTAACGTCTACACCAGAATTGCACAAAACCAACAATGACAAGTCGGTAGC
GCGAGCAACTATCGCTGTCAACCGTCGTTACAAAGACCAAAACGGTGAACGTGAAGCTGATTTTGTCAATATGGTCCTAT
GGGGCAGACTAGCAGAAACTTTGGCAAGCTACGCAACCAAAGGTAGTCTCATTTCCGTTGATGGAGAATTGCGTACCCGT
CGCTTTGAGAAAAATGGTCAGATGAACTATGTAACCGAAGTCCTTGTGACAGGATTCCAACTCTTAGAAAGTCGTGCTCA
ACGTGCCATGCGTGAAAATAATGCAGGCCAAGATTTGGCAGATTTGGTCTTGGAAGAGGAAGAATTGCCATTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A098Z0L0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbB/cilA Streptococcus pneumoniae D39

100

100

1

  ssbB/cilA Streptococcus pneumoniae Rx1

100

100

1

  ssbB/cilA Streptococcus pneumoniae R6

100

100

1

  ssbB/cilA Streptococcus pneumoniae TIGR4

99.237

100

0.992

  ssbB/cilA Streptococcus mitis SK321

98.473

100

0.985

  ssbB/cilA Streptococcus mitis NCTC 12261

98.473

100

0.985

  ssbA Streptococcus mutans UA159

74.809

100

0.748

  ssbB Streptococcus sobrinus strain NIDR 6715-7

70.229

100

0.702

  ssbB Lactococcus lactis subsp. cremoris KW2

59.821

85.496

0.511

  ssbA Bacillus subtilis subsp. subtilis str. 168

50.943

80.916

0.412

  ssb Latilactobacillus sakei subsp. sakei 23K

46.903

86.26

0.405


Multiple sequence alignment