Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   FIV04_RS12230 Genome accession   NZ_CP045338
Coordinates   2757063..2758292 (+) Length   409 a.a.
NCBI ID   WP_172974246.1    Uniprot ID   A0A5P9BAB5
Organism   Vibrio sp. THAF190c     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2752063..2763292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FIV04_RS12205 (FIV04_12260) ampD 2753058..2753606 (-) 549 WP_152469275.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  FIV04_RS12215 (FIV04_12265) nadC 2753755..2754645 (+) 891 WP_032550149.1 carboxylating nicotinate-nucleotide diphosphorylase -
  FIV04_RS12220 (FIV04_12270) pilA 2754899..2755330 (+) 432 WP_152469276.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  FIV04_RS12225 (FIV04_12275) pilB 2755331..2757016 (+) 1686 WP_152469277.1 type IV-A pilus assembly ATPase PilB Machinery gene
  FIV04_RS12230 (FIV04_12280) pilC 2757063..2758292 (+) 1230 WP_172974246.1 type II secretion system F family protein Machinery gene
  FIV04_RS12235 (FIV04_12285) pilD 2758352..2759221 (+) 870 WP_152469278.1 A24 family peptidase Machinery gene
  FIV04_RS12240 (FIV04_12290) coaE 2759225..2759833 (+) 609 WP_152469279.1 dephospho-CoA kinase -
  FIV04_RS12245 (FIV04_12295) zapD 2759866..2760606 (+) 741 WP_032550155.1 cell division protein ZapD -
  FIV04_RS12250 (FIV04_12300) yacG 2760694..2760891 (+) 198 WP_032550156.1 DNA gyrase inhibitor YacG -
  FIV04_RS12260 (FIV04_12305) rplS 2761292..2761645 (-) 354 WP_032549758.1 50S ribosomal protein L19 -
  FIV04_RS12265 (FIV04_12310) trmD 2761705..2762445 (-) 741 WP_150869263.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  FIV04_RS12270 (FIV04_12315) rimM 2762473..2763027 (-) 555 WP_032549760.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45035.28 Da        Isoelectric Point: 10.4674

>NTDB_id=393494 FIV04_RS12230 WP_172974246.1 2757063..2758292(+) (pilC) [Vibrio sp. THAF190c]
MAIKPKQSQLKNYHWRGVNSSGKKVSGQTLALTELEVRDKLRGQHIQIKKIKKKSISALTRLTHRVKAKDITLLSRQLAT
MLGTGVPIIQAIKLVSDNHRKAEMKSILSQICKGVEAGTPLSKAMRTASRHFDGLYTDLVATGELSGNLAEVFERLANYR
EKSERLKSKVIKALIYPVMVVVTALTVSFLMLTMVIPEFESMFSGFGADLPWFTAKVMALSHWMQAYSLYTLLGFAGAIL
FVIQARKRSYSIRLALSRLGLKLPIIGGVIAKASIAKFSRTLSTSFSSGIPILTSLRTTAKTTGNIHFESAITEIHKETA
AGMPMYIAMRNSQAFPEMVLQMVMIGEESGNLDEMLTKVATIYEFEVDDTVDNLGKILEPVIIVFLGSVVGGLVVAMYLP
IFNLMSVLG

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=393494 FIV04_RS12230 WP_172974246.1 2757063..2758292(+) (pilC) [Vibrio sp. THAF190c]
ATGGCAATCAAACCCAAACAATCACAACTCAAGAATTATCACTGGAGAGGCGTTAACAGCTCAGGGAAAAAAGTGTCAGG
GCAAACCTTGGCTCTCACGGAACTTGAAGTCAGAGACAAGCTGCGCGGACAGCACATCCAGATTAAGAAGATAAAGAAAA
AAAGCATCTCGGCGCTGACTCGCCTAACCCATAGGGTCAAAGCAAAAGACATCACTCTGCTCTCACGCCAACTGGCAACC
ATGCTAGGAACTGGTGTCCCTATAATCCAAGCCATCAAGTTGGTGTCAGATAATCATAGAAAAGCAGAGATGAAATCGAT
CTTGTCGCAGATCTGCAAAGGCGTTGAAGCGGGGACCCCTCTATCAAAAGCGATGAGAACTGCAAGCCGTCATTTTGATG
GCTTGTATACCGACCTTGTGGCAACCGGAGAACTGTCTGGAAATCTCGCTGAGGTCTTTGAAAGGCTGGCTAACTATCGA
GAGAAAAGTGAACGCTTAAAATCAAAAGTCATAAAAGCGCTCATCTACCCGGTGATGGTGGTTGTCACCGCTTTAACGGT
CTCATTTCTAATGCTGACAATGGTGATCCCTGAGTTTGAATCTATGTTCTCAGGCTTTGGTGCCGATCTCCCTTGGTTCA
CCGCAAAGGTGATGGCGCTATCGCACTGGATGCAAGCTTACAGCCTTTATACTTTGCTTGGCTTTGCAGGTGCTATTCTC
TTTGTCATTCAAGCTCGCAAGCGCTCCTATTCCATAAGGCTGGCCCTTAGCAGATTAGGACTCAAACTTCCTATCATAGG
AGGGGTCATAGCCAAAGCTTCCATCGCCAAATTCAGCCGCACATTATCAACCAGTTTTAGCTCTGGCATCCCGATCCTAA
CCAGCCTCAGAACTACCGCTAAAACCACAGGTAACATACATTTTGAATCCGCCATTACAGAGATCCATAAAGAGACAGCT
GCAGGGATGCCGATGTATATCGCAATGCGCAACAGCCAGGCCTTTCCTGAAATGGTATTGCAGATGGTGATGATAGGCGA
GGAGTCTGGCAACCTAGACGAGATGCTCACCAAGGTTGCGACCATCTATGAGTTTGAAGTAGACGATACCGTCGATAACT
TAGGCAAAATCTTAGAGCCGGTCATCATCGTTTTTCTGGGTTCAGTAGTGGGTGGCTTAGTGGTTGCGATGTACTTACCG
ATCTTTAATCTAATGAGTGTGTTAGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(75-197)

Type II secretion system (T2SS), protein F (T2SSF)

(278-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5P9BAB5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

77.75

97.8

0.76
  pilC Vibrio campbellii strain DS40M4

68.579

98.044

0.672
  pilC Acinetobacter baumannii D1279779

42.298

100

0.423
  pilC Legionella pneumophila strain ERS1305867

42.714

97.311

0.416
  pilC Acinetobacter baylyi ADP1

42.821

97.066

0.416
  pilC Pseudomonas stutzeri DSM 10701

42.079

98.778

0.416
  pilG Neisseria gonorrhoeae MS11

39.303

98.289

0.386
  pilG Neisseria meningitidis 44/76-A

39.055

98.289

0.384

Multiple sequence alignment