Detailed information NTG0393495

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FIV04_RS12235
• Genome accession: NZ_CP045338
• Coordinates: 2758352..2759221 (+)
• Length: 289 a.a.
• NCBI ID: WP_152469278.1
• Uniprot ID: A0A5P9B9M1
• Organism: Vibrio sp. THAF190c
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2753352..2764221

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIV04_RS12215 (FIV04_12265)	nadC	2753755..2754645 (+)	891	WP_032550149.1	carboxylating nicotinate-nucleotide diphosphorylase	-
FIV04_RS12220 (FIV04_12270)	pilA	2754899..2755330 (+)	432	WP_152469276.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
FIV04_RS12225 (FIV04_12275)	pilB	2755331..2757016 (+)	1686	WP_152469277.1	type IV-A pilus assembly ATPase PilB	Machinery gene
FIV04_RS12230 (FIV04_12280)	pilC	2757063..2758292 (+)	1230	WP_172974246.1	type II secretion system F family protein	Machinery gene
FIV04_RS12235 (FIV04_12285)	pilD	2758352..2759221 (+)	870	WP_152469278.1	A24 family peptidase	Machinery gene
FIV04_RS12240 (FIV04_12290)	coaE	2759225..2759833 (+)	609	WP_152469279.1	dephospho-CoA kinase	-
FIV04_RS12245 (FIV04_12295)	zapD	2759866..2760606 (+)	741	WP_032550155.1	cell division protein ZapD	-
FIV04_RS12250 (FIV04_12300)	yacG	2760694..2760891 (+)	198	WP_032550156.1	DNA gyrase inhibitor YacG	-
FIV04_RS12260 (FIV04_12305)	rplS	2761292..2761645 (-)	354	WP_032549758.1	50S ribosomal protein L19	-
FIV04_RS12265 (FIV04_12310)	trmD	2761705..2762445 (-)	741	WP_150869263.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
FIV04_RS12270 (FIV04_12315)	rimM	2762473..2763027 (-)	555	WP_032549760.1	ribosome maturation factor RimM	-
FIV04_RS12275 (FIV04_12320)	rpsP	2763056..2763304 (-)	249	WP_004410028.1	30S ribosomal protein S16	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32624.88 Da
• Isoelectric Point: 7.6096

>NTDB_id=393495 FIV04_RS12235 WP_152469278.1 2758352..2759221(+) (pilD) [Vibrio sp. THAF190c]
MEVFHYYPWLFPVLAFIFSLLIGSFLNVVIHRLPIMMEREWQQECSESFPDYKIPMPKGTYNLSVPRSTCPKCETQIRAI
DNIPVLSWLFLKGKCRKCSNPISPRYPFVELLTAVMCSFVAVHFGFSYYAIALIFFTFALIAATFIDLDTMLLPDQITLP
LVWSGIALALFGISPISLQDSVIGAMAGYLALWSVYWLFKLLTGKEGMGYGDFKLLAALGAWLGWQHLPMIILTSSLVGL
VFGLIQLRLKQQGIDKAFPFGPYLAIAGWISLIWGENIMAWYFTSVLGI

Nucleotide

• Length: 870 bp

>NTDB_id=393495 FIV04_RS12235 WP_152469278.1 2758352..2759221(+) (pilD) [Vibrio sp. THAF190c]
ATGGAAGTATTTCACTACTATCCTTGGCTATTCCCCGTATTAGCTTTTATCTTCAGCCTACTCATCGGTAGTTTTCTCAA
CGTCGTTATCCATCGTTTACCAATTATGATGGAGCGAGAGTGGCAACAAGAGTGCTCTGAGAGCTTTCCTGATTATAAGA
TTCCGATGCCAAAGGGGACGTATAACCTCAGCGTGCCTCGTTCGACATGTCCAAAGTGTGAAACGCAGATCCGAGCCATC
GATAATATTCCGGTACTCAGCTGGTTATTTTTGAAAGGCAAATGTCGAAAGTGTTCGAACCCAATCAGTCCACGCTACCC
TTTCGTAGAGCTACTCACTGCAGTGATGTGTAGCTTTGTCGCGGTTCACTTTGGCTTTAGTTACTACGCAATCGCACTGA
TCTTTTTTACCTTTGCTTTGATCGCGGCGACCTTCATCGACCTTGACACCATGCTACTGCCTGATCAAATCACTCTACCA
TTGGTCTGGTCAGGGATTGCGCTTGCATTGTTTGGCATTAGTCCTATCTCCCTCCAAGATTCTGTAATAGGAGCAATGGC
AGGCTATCTGGCTCTATGGTCAGTCTACTGGCTATTCAAACTCCTTACAGGCAAAGAGGGAATGGGCTATGGCGATTTCA
AACTCCTTGCAGCATTAGGGGCTTGGCTTGGTTGGCAACACCTACCGATGATCATACTGACCTCTTCACTTGTCGGTCTT
GTATTTGGCTTAATTCAGCTGCGATTGAAACAGCAAGGCATCGACAAAGCCTTTCCTTTTGGTCCTTACCTCGCCATTGC
CGGTTGGATAAGTTTGATTTGGGGCGAGAACATTATGGCTTGGTATTTTACTTCGGTTTTAGGAATTTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (135-244)

3D structure

• AlphaFold DB: A0A5P9B9M1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	75.779	100	0.758
pilD	Vibrio cholerae strain A1552	69.097	99.654	0.689
pilD	Acinetobacter baumannii D1279779	51.119	92.734	0.474
pilD	Acinetobacter nosocomialis M2	51.119	92.734	0.474
pilD	Neisseria gonorrhoeae MS11	46.715	94.81	0.443