Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   FOB76_RS03680 Genome accession   NZ_CP044093
Coordinates   703941..704267 (-) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain FDAARGOS_668     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 698941..709267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB76_RS03645 (FOB76_03645) - 699759..700067 (-) 309 WP_032461811.1 hypothetical protein -
  FOB76_RS03650 (FOB76_03650) - 700254..701450 (-) 1197 WP_123949427.1 acetate kinase -
  FOB76_RS03655 (FOB76_03655) comYH 701509..702462 (-) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  FOB76_RS03660 (FOB76_03660) comGG 702560..702886 (-) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  FOB76_RS03665 (FOB76_03665) comYF 702870..703304 (-) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOB76_RS03670 (FOB76_03670) comGE 703297..703581 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  FOB76_RS03675 (FOB76_03675) comGD 703538..703966 (-) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  FOB76_RS03680 (FOB76_03680) comYC 703941..704267 (-) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  FOB76_RS03685 (FOB76_03685) comYB 704269..705303 (-) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOB76_RS03690 (FOB76_03690) comYA 705239..706177 (-) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  FOB76_RS03695 (FOB76_03695) - 706270..706635 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=387744 FOB76_RS03680 WP_002986552.1 703941..704267(-) (comYC) [Streptococcus pyogenes strain FDAARGOS_668]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=387744 FOB76_RS03680 WP_002986552.1 703941..704267(-) (comYC) [Streptococcus pyogenes strain FDAARGOS_668]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGTTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment