Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   FOB76_RS03655 Genome accession   NZ_CP044093
Coordinates   701509..702462 (-) Length   317 a.a.
NCBI ID   WP_002987790.1    Uniprot ID   A0A5S4TCX5
Organism   Streptococcus pyogenes strain FDAARGOS_668     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 696509..707462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB76_RS03620 (FOB76_03620) - 696728..697045 (-) 318 WP_002987805.1 thioredoxin family protein -
  FOB76_RS03625 (FOB76_03625) - 697045..697326 (-) 282 WP_024623420.1 DUF4651 domain-containing protein -
  FOB76_RS03635 (FOB76_03635) pepA 697791..698858 (+) 1068 WP_002987798.1 glutamyl aminopeptidase -
  FOB76_RS03640 (FOB76_03640) proC 698906..699676 (+) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -
  FOB76_RS03645 (FOB76_03645) - 699759..700067 (-) 309 WP_032461811.1 hypothetical protein -
  FOB76_RS03650 (FOB76_03650) - 700254..701450 (-) 1197 WP_123949427.1 acetate kinase -
  FOB76_RS03655 (FOB76_03655) comYH 701509..702462 (-) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  FOB76_RS03660 (FOB76_03660) comGG 702560..702886 (-) 327 WP_002987787.1 competence type IV pilus minor pilin ComGG -
  FOB76_RS03665 (FOB76_03665) comYF 702870..703304 (-) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOB76_RS03670 (FOB76_03670) comGE 703297..703581 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  FOB76_RS03675 (FOB76_03675) comGD 703538..703966 (-) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  FOB76_RS03680 (FOB76_03680) comYC 703941..704267 (-) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  FOB76_RS03685 (FOB76_03685) comYB 704269..705303 (-) 1035 WP_223845212.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOB76_RS03690 (FOB76_03690) comYA 705239..706177 (-) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  FOB76_RS03695 (FOB76_03695) - 706270..706635 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35985.08 Da        Isoelectric Point: 4.7205

>NTDB_id=387742 FOB76_RS03655 WP_002987790.1 701509..702462(-) (comYH) [Streptococcus pyogenes strain FDAARGOS_668]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=387742 FOB76_RS03655 WP_002987790.1 701509..702462(-) (comYH) [Streptococcus pyogenes strain FDAARGOS_668]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGTCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TCX5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

66.139

99.685

0.659
  comYH Streptococcus mutans UA140

65.823

99.685

0.656

Multiple sequence alignment