Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FY406_RS02325 Genome accession   NZ_CP043405
Coordinates   496089..497345 (-) Length   418 a.a.
NCBI ID   WP_003089911.1    Uniprot ID   -
Organism   Streptococcus ratti strain ATCC 31377     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 491089..502345
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS02290 (FY406_02290) ruvX 491454..491873 (-) 420 WP_003090938.1 Holliday junction resolvase RuvX -
  FY406_RS02295 (FY406_02295) - 491870..492139 (-) 270 WP_003089901.1 IreB family regulatory phosphoprotein -
  FY406_RS02300 (FY406_02300) brsR 492306..492740 (+) 435 WP_003089903.1 LytTR family DNA-binding domain-containing protein Regulator
  FY406_RS02305 (FY406_02305) brsM 492755..493201 (+) 447 WP_003089904.1 DUF3021 domain-containing protein Regulator
  FY406_RS02310 (FY406_02310) - 493408..493827 (-) 420 WP_003089906.1 hypothetical protein -
  FY406_RS02315 (FY406_02315) spx 494415..494813 (-) 399 WP_003089907.1 transcriptional regulator Spx -
  FY406_RS02320 (FY406_02320) recA 494898..496046 (-) 1149 WP_003089908.1 recombinase RecA Machinery gene
  FY406_RS02325 (FY406_02325) cinA 496089..497345 (-) 1257 WP_003089911.1 competence/damage-inducible protein A Machinery gene
  FY406_RS02330 (FY406_02330) - 497625..498185 (-) 561 WP_003089912.1 DNA-3-methyladenine glycosylase I -
  FY406_RS02335 (FY406_02335) ruvA 498223..498816 (-) 594 WP_003089915.1 Holliday junction branch migration protein RuvA -
  FY406_RS02340 (FY406_02340) mutL 499101..501056 (-) 1956 WP_003089917.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45288.86 Da        Isoelectric Point: 4.9885

>NTDB_id=383555 FY406_RS02325 WP_003089911.1 496089..497345(-) (cinA) [Streptococcus ratti strain ATCC 31377]
MKAEIIAVGTEILLGQIVNTNAQFLSEKLAQLGIDVYFQTAVGDNEERLLSVLEIAKGRSDLVILCGGLGPTEDDLTKQT
LAKFLGRDLVFDQAAQVRLDEFFASRPASARTPNNERQAQIVAGSSPLPNVTGLAVGGILVAEGVTYVVLPGPPSELKPM
VNQELLPYLSETSEQLYSRVLRFFGIGESRLVTLLHDLIDRQTDPTIAPYAKTGEVTIRLSTKAYSQKEADAKLAQAEKE
ILAVDRLSDYLYGYGEDNSLAQVVFDLLKEKRKTITAAESLTAGLFQARLADFAGASDIFKGGFVTYSIEEKAKMLNIPL
EELKKHGVVSDFTAKKMAEQSRLLTGADWAVSLTGVAGPDQLEDQPAGTVFIGLASAQGTLSRKVLIGGRSRSDVRYIAV
LHAFNLVRQALLSKENLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=383555 FY406_RS02325 WP_003089911.1 496089..497345(-) (cinA) [Streptococcus ratti strain ATCC 31377]
ATGAAAGCTGAGATTATTGCTGTAGGGACAGAGATTTTGCTGGGGCAGATTGTCAATACCAATGCGCAGTTTTTGTCAGA
AAAGCTGGCACAGCTGGGGATTGATGTTTATTTTCAGACGGCAGTAGGTGACAATGAAGAGCGTCTTTTGTCTGTCTTAG
AAATTGCTAAAGGCCGCAGCGATTTAGTAATACTTTGCGGCGGCTTAGGGCCGACAGAAGATGATTTAACCAAGCAGACT
CTGGCAAAATTTCTAGGAAGAGATTTGGTTTTTGACCAAGCTGCTCAGGTTCGCCTAGATGAATTTTTTGCTTCCCGTCC
GGCCTCGGCCCGCACTCCCAATAATGAACGTCAGGCGCAGATTGTGGCAGGAAGCAGCCCGCTCCCTAACGTTACGGGTT
TAGCTGTAGGCGGTATTTTAGTAGCTGAAGGAGTGACTTATGTCGTACTGCCGGGTCCGCCGAGCGAATTAAAGCCTATG
GTTAATCAGGAGCTCTTGCCTTATCTATCTGAAACATCCGAACAGCTCTATTCGCGCGTGCTGCGTTTTTTCGGTATTGG
CGAGAGCCGGTTGGTTACCTTGCTGCACGACCTGATTGATAGGCAGACAGATCCTACTATTGCTCCCTATGCCAAGACAG
GAGAAGTGACGATTCGCCTGTCAACAAAGGCTTACAGCCAAAAAGAAGCAGATGCTAAGCTGGCTCAGGCGGAAAAAGAA
ATTTTAGCCGTTGACCGTTTGTCTGATTATCTTTACGGCTATGGTGAGGACAATTCACTGGCTCAGGTGGTCTTTGACCT
GCTCAAAGAGAAGAGAAAAACAATCACAGCAGCTGAAAGTTTAACGGCAGGCTTATTCCAAGCAAGGCTGGCAGATTTTG
CAGGGGCTTCGGATATTTTTAAAGGTGGTTTTGTCACTTATAGTATAGAAGAAAAAGCTAAAATGCTGAATATTCCGCTT
GAAGAGCTGAAAAAACACGGTGTTGTCAGTGATTTTACCGCTAAAAAAATGGCGGAGCAATCACGGCTTCTGACAGGAGC
AGACTGGGCTGTTTCTCTGACTGGAGTAGCCGGTCCCGATCAACTGGAAGATCAGCCGGCAGGGACGGTCTTTATCGGGC
TGGCAAGTGCTCAGGGAACCTTGTCGCGCAAGGTTTTGATTGGGGGTCGCAGTCGGTCTGATGTGCGTTACATTGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAGCTTTATTATCTAAGGAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(258-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

82.775

100

0.828
  cinA Streptococcus mitis SK321

73.445

100

0.734
  cinA Streptococcus mitis NCTC 12261

73.206

100

0.732
  cinA Streptococcus pneumoniae TIGR4

72.01

100

0.72
  cinA Streptococcus pneumoniae Rx1

71.77

100

0.718
  cinA Streptococcus pneumoniae R6

71.77

100

0.718
  cinA Streptococcus pneumoniae D39

71.531

100

0.715
  cinA Streptococcus suis isolate S10

56.204

98.325

0.553
  cinA Bacillus subtilis subsp. subtilis str. 168

46.394

99.522

0.462

Multiple sequence alignment