Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   NHAL_RS18660 Genome accession   NC_013960
Coordinates   3967649..3968869 (+) Length   406 a.a.
NCBI ID   WP_013034709.1    Uniprot ID   D5C3F3
Organism   Nitrosococcus halophilus Nc 4     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3962649..3973869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NHAL_RS18640 (Nhal_3843) dapF 3962714..3963544 (-) 831 WP_013034704.1 diaminopimelate epimerase -
  NHAL_RS18645 (Nhal_3844) - 3963576..3964262 (-) 687 WP_013034705.1 class I SAM-dependent methyltransferase -
  NHAL_RS18650 (Nhal_3845) lysA 3964323..3965573 (-) 1251 WP_013034706.1 diaminopimelate decarboxylase -
  NHAL_RS20750 (Nhal_3846) lptM 3965577..3965711 (-) 135 WP_013034707.1 LPS translocon maturation chaperone LptM -
  NHAL_RS18655 (Nhal_3847) pilB 3965929..3967644 (+) 1716 WP_041355203.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NHAL_RS18660 (Nhal_3848) pilC 3967649..3968869 (+) 1221 WP_013034709.1 type II secretion system F family protein Machinery gene
  NHAL_RS18665 (Nhal_3849) pilD 3968889..3969758 (+) 870 WP_013034710.1 prepilin peptidase Machinery gene
  NHAL_RS18670 (Nhal_3850) coaE 3969808..3970407 (+) 600 WP_013034711.1 dephospho-CoA kinase -
  NHAL_RS18675 (Nhal_3851) zapD 3970503..3971270 (+) 768 WP_013034712.1 cell division protein ZapD -
  NHAL_RS18680 (Nhal_3852) - 3971267..3971455 (+) 189 WP_013034713.1 DNA gyrase inhibitor YacG -
  NHAL_RS18685 (Nhal_3853) - 3971574..3972530 (-) 957 WP_013034714.1 Nudix family hydrolase -
  NHAL_RS18690 (Nhal_3854) - 3972583..3972783 (+) 201 WP_041355205.1 DUF2905 domain-containing protein -
  NHAL_RS18695 (Nhal_3855) - 3972857..3973084 (-) 228 WP_013034716.1 zinc-finger domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44374.37 Da        Isoelectric Point: 10.2418

>NTDB_id=36774 NHAL_RS18660 WP_013034709.1 3967649..3968869(+) (pilC) [Nitrosococcus halophilus Nc 4]
MAQAATKQQIFVWEGANRQGQRVKGEVNGKNTSMVKADLRRQGIVPLKVRKKPTPLFGRRKKKITPKEIAIFSRQLATMM
SAGVPLVQAFEIIGRGHENASMQALVLNIKGEVEGGGTLAEALKKHPRQFDDLFCNLVNAGEQSGTLETLLDKIATYKEK
TEAIKGKIKKALFYPTAVVVVAFIITAILLIFVIPQFQTLFQNFGADLPALTLLVLQLSALFQEWWWAIFGGMGVAIYSL
IEARRRSRKINHLFDKLLLKLPVIGEILNKATIARYARTLSTMFAAGVPLVEAMASVAGAAGNSVYAQGILRIRDEVSTG
TQLQAAMRNSQLFPNMVVQMVAIGEEAGSIDQMLAKVADFYEEEVDNAVDALSSLLEPLIMAILGVLVGGLVIAMYLPIF
KMGSVV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=36774 NHAL_RS18660 WP_013034709.1 3967649..3968869(+) (pilC) [Nitrosococcus halophilus Nc 4]
ATGGCGCAAGCGGCAACAAAACAACAGATTTTTGTCTGGGAAGGCGCCAACCGGCAGGGGCAGCGGGTTAAGGGCGAGGT
CAACGGCAAAAACACCAGCATGGTGAAAGCCGATCTCCGGCGACAAGGCATTGTACCCTTAAAGGTCCGCAAAAAACCCA
CGCCTTTGTTTGGCCGGCGCAAGAAAAAAATCACCCCTAAGGAGATTGCCATCTTTAGCCGCCAACTGGCGACGATGATG
TCCGCGGGCGTACCGTTGGTTCAGGCCTTTGAAATTATAGGCCGCGGCCATGAAAATGCCTCCATGCAAGCGCTGGTCCT
GAATATCAAGGGGGAAGTGGAGGGTGGCGGCACGCTGGCTGAAGCCCTCAAAAAACACCCCAGGCAATTTGACGACCTTT
TTTGTAACCTGGTCAATGCCGGGGAGCAGTCCGGTACCCTCGAGACTTTGCTGGATAAAATCGCCACTTACAAAGAAAAG
ACAGAGGCCATCAAGGGAAAGATTAAAAAAGCACTCTTCTATCCTACCGCCGTGGTGGTGGTGGCTTTTATCATTACCGC
AATTTTGCTTATCTTCGTTATCCCCCAATTTCAAACCTTGTTCCAGAATTTCGGTGCCGATCTCCCCGCCCTCACCTTAT
TAGTGCTCCAGCTTTCCGCCCTCTTTCAAGAGTGGTGGTGGGCCATTTTTGGGGGCATGGGAGTCGCCATTTATAGCCTT
ATCGAAGCCAGGCGGCGCTCACGCAAAATCAACCATCTCTTCGATAAATTACTACTCAAGCTGCCGGTAATTGGCGAAAT
CCTAAATAAGGCCACTATCGCCCGCTATGCCCGTACCCTCTCGACCATGTTTGCTGCCGGCGTTCCCTTAGTTGAAGCCA
TGGCCTCTGTGGCTGGCGCTGCTGGCAACTCCGTTTATGCTCAGGGCATCCTCCGCATACGCGATGAGGTCTCCACCGGG
ACCCAGTTACAGGCAGCTATGCGCAACAGCCAATTATTTCCTAATATGGTGGTGCAGATGGTGGCCATTGGTGAAGAAGC
AGGCTCAATCGATCAGATGCTGGCCAAAGTGGCAGATTTCTATGAGGAGGAAGTCGATAATGCCGTTGATGCCCTCAGTA
GCTTGCTAGAGCCGCTTATCATGGCGATACTAGGGGTTTTGGTGGGTGGCCTTGTTATCGCCATGTACTTACCCATCTTC
AAGATGGGGTCGGTCGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D5C3F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

59.852

100

0.599
  pilC Legionella pneumophila strain ERS1305867

59.848

97.537

0.584
  pilC Acinetobacter baylyi ADP1

56.757

100

0.569
  pilC Acinetobacter baumannii D1279779

57.683

97.783

0.564
  pilG Neisseria meningitidis 44/76-A

47.146

99.261

0.468
  pilG Neisseria gonorrhoeae MS11

46.898

99.261

0.466
  pilC Vibrio cholerae strain A1552

41.919

97.537

0.409
  pilC Vibrio campbellii strain DS40M4

39.756

100

0.401
  pilC Thermus thermophilus HB27

35.407

100

0.365

Multiple sequence alignment