Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   FGM04_RS15930 Genome accession   NZ_CP040717
Coordinates   3427939..3429180 (-) Length   413 a.a.
NCBI ID   WP_005355091.1    Uniprot ID   A0A2T4MY12
Organism   Aeromonas veronii strain HX3     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3422939..3434180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGM04_RS15900 (FGM04_15920) - 3423739..3424923 (+) 1185 WP_157161845.1 tetratricopeptide repeat protein -
  FGM04_RS15905 (FGM04_15925) mutT 3424932..3425336 (+) 405 WP_042053534.1 8-oxo-dGTP diphosphatase MutT -
  FGM04_RS15910 (FGM04_15930) yacG 3425413..3425607 (-) 195 WP_005336142.1 DNA gyrase inhibitor YacG -
  FGM04_RS15915 (FGM04_15935) zapD 3425617..3426339 (-) 723 WP_005355104.1 cell division protein ZapD -
  FGM04_RS15920 (FGM04_15940) coaE 3426377..3426991 (-) 615 WP_139478393.1 dephospho-CoA kinase -
  FGM04_RS15925 (FGM04_15945) pilD 3427005..3427877 (-) 873 WP_157161846.1 A24 family peptidase Machinery gene
  FGM04_RS15930 (FGM04_15950) pilC 3427939..3429180 (-) 1242 WP_005355091.1 type II secretion system F family protein Machinery gene
  FGM04_RS15935 (FGM04_15955) pilB 3429420..3431126 (-) 1707 WP_005356616.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  FGM04_RS22440 (FGM04_15960) - 3431129..3431515 (-) 387 WP_100646864.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  FGM04_RS15945 (FGM04_15970) nadC 3431831..3432694 (-) 864 WP_064339261.1 carboxylating nicotinate-nucleotide diphosphorylase -
  FGM04_RS15950 (FGM04_15975) - 3432698..3433168 (-) 471 WP_157161847.1 TIGR02281 family clan AA aspartic protease -
  FGM04_RS15955 (FGM04_15980) ampD 3433299..3433874 (+) 576 WP_069554218.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45441.57 Da        Isoelectric Point: 9.7221

>NTDB_id=366775 FGM04_RS15930 WP_005355091.1 3427939..3429180(-) (pilC) [Aeromonas veronii strain HX3]
MATLTKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGEVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=366775 FGM04_RS15930 WP_005355091.1 3427939..3429180(-) (pilC) [Aeromonas veronii strain HX3]
ATGGCAACCCTAACGAAAAAGAACAATGCCCCCAAGAAAGTCTTCGCCTTCCGCTGGCACGGGGTAAACCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTGCAGGCCGACAGCATCAACACCGTCAAGACCGAACTACGCAAGCAGGGGGTCAACGTCACCA
AGGTAGCCAAGAAATCCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAACCGATGGATATCGCCATCGTCTCACGC
CAGATCACCACCATGCTCTCCGCCGGTGTACCACTGGTGCAGAGCCTGCAGATCATCGCCCGCAGTCACGAGAAAGCCTC
GATGCGCGAGCTGATGGGGCAGATTGCCGCCGATGTGGAGACCGGTACCCCCATGTCGGAGGCGCTGCGTCGCCATCCCC
TCTACTTTGACGATCTCTACTGCGATCTGGTGGAAGCCGGTGAGCAATCCGGTGCGCTGGAAACCATCTACGACCGTATC
GCCACCTATCGGGAAAAGTCGGAAGCGCTCAAGTCGAAGATCAAGAAGGCGATGTTCTACCCCACCATGGTCATTCTGGT
CGCCATCGTGGTCACCTCCATCCTGCTGCTGTTCGTCATTCCACAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCGGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACGGCC
CTTGGCATCTTCCTTTACGTGCGGGCCTGGCGGGCCTCCCAGAAGGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTGGTCGGGATGATCCTGCACAAGGCGGCGATGGCTCGCTTTGCCCGCACCCTGTCGACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCGCTTATATCGGCAGCAGGTGCCTCCGGCAACTATGTCTATCGCACCGCGGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGTATGCAGATCAACGTGGCAATGCGCACCGTCGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGTGAGGAGTCCGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGACT
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATCGCC
ATGTACCTGCCCATCTTCAAGCTGGGCGAAGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2T4MY12

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

50.985

98.305

0.501
  pilC Vibrio cholerae strain A1552

46.883

97.094

0.455
  pilC Vibrio campbellii strain DS40M4

45.792

97.821

0.448
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

38

96.852

0.368

Multiple sequence alignment