Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SMI_RS09335 Genome accession   NC_013853
Coordinates   1902697..1903953 (-) Length   418 a.a.
NCBI ID   WP_000642685.1    Uniprot ID   D3HB30
Organism   Streptococcus mitis B6     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1897697..1908953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS09315 (smi_1836) - 1898551..1899012 (-) 462 WP_000360516.1 MarR family winged helix-turn-helix transcriptional regulator -
  SMI_RS09320 (smi_1837) - 1899190..1899906 (-) 717 WP_000532885.1 YebC/PmpR family DNA-binding transcriptional regulator -
  SMI_RS09325 (smi_1838) - 1900003..1901373 (-) 1371 WP_001036258.1 MATE family efflux transporter -
  SMI_RS09330 (smi_1839) recA 1901488..1902642 (-) 1155 WP_001085455.1 recombinase RecA Machinery gene
  SMI_RS09335 (smi_1840) cinA 1902697..1903953 (-) 1257 WP_000642685.1 competence/damage-inducible protein A Machinery gene
  SMI_RS09340 (smi_1841) brpA 1904031..1905086 (-) 1056 WP_000239268.1 biofilm formation/cell division transcriptional regulator BrpA -
  SMI_RS09345 (smi_1842) - 1905094..1905612 (-) 519 WP_000455529.1 GNAT family N-acetyltransferase -
  SMI_RS09350 (smi_1843) tsaE 1905602..1906045 (-) 444 WP_000288245.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  SMI_RS09355 (smi_1844) comM 1906141..1906770 (-) 630 WP_000413915.1 competence protein Regulator
  SMI_RS09360 (smi_1845) ndk 1906904..1907326 (-) 423 WP_000438298.1 nucleoside-diphosphate kinase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45103.41 Da        Isoelectric Point: 4.5751

>NTDB_id=36339 SMI_RS09335 WP_000642685.1 1902697..1903953(-) (cinA) [Streptococcus mitis B6]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDPQAQEKLDVFFAQRPDYARTPNNERQAQIVEGATPLPNETGLAVGGILEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILSDLIDNQTDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDRQTFEGISLRDLCYGYGEEASLASIVVEKLKKQGKTITAAESLTAGLFQARVADFSGASSIFKGGFVTYSLEEKSKIL
DIPVKDLEEQGVVSEFTAQKMAEQARIKTQSDFGISLTGVAGPDSLEGHPAGTVYIGLAQEQGTEVIKVNIGGRSRADIR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=36339 SMI_RS09335 WP_000642685.1 1902697..1903953(-) (cinA) [Streptococcus mitis B6]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
AAAACTAGCAGAAATTGGAGTAGACGTATATTTTCAGACGGCTGTGGGAGACAATGAAGCTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGTAGTCTGGTGATTTTAACAGGTGGTTTGGGACCAACTGAGGACGATTTGACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGAATTAGTCTTCGATCCTCAGGCTCAGGAGAAGTTAGATGTCTTTTTTGCCCAGCGACC
AGACTATGCCCGAACACCAAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGACTCCACTGCCCAACGAAACAGGAC
TGGCTGTGGGAGGCATTTTGGAAGTCGATGGAGTGACCTATGTCGTCCTTCCCGGTCCACCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGTAAGCTATATTCCCGAGTTCTTCGTTTCTTTGGAATTGGCGA
GAGCCAGTTGGTTACGATTTTGTCTGATTTGATTGATAATCAAACAGATCCGACCTTGGCCCCTTATGCTAAGACAGGAG
AAGTCACTCTGCGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACCGCCAGACTTTCGAAGGAATTTCTTTACGAGACCTCTGTTATGGTTATGGAGAGGAGGCTAGCTTGGCCAGCAT
TGTGGTAGAAAAACTGAAAAAACAAGGGAAAACTATCACGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCCAGAG
TAGCGGATTTTTCGGGTGCTTCAAGTATATTTAAGGGTGGTTTTGTAACCTATAGCTTGGAGGAGAAATCAAAGATATTG
GATATTCCTGTCAAGGACTTGGAAGAACAGGGTGTGGTGTCTGAATTTACAGCACAGAAGATGGCTGAACAGGCACGAAT
CAAGACCCAGTCTGATTTTGGCATTAGCTTGACTGGAGTAGCAGGGCCAGATAGTCTAGAAGGTCATCCAGCTGGGACAG
TTTACATAGGCTTGGCACAGGAGCAAGGAACTGAGGTCATCAAGGTCAATATTGGAGGCAGAAGCCGAGCAGATATACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3HB30

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

97.368

100

0.974
  cinA Streptococcus mitis NCTC 12261

96.651

100

0.967
  cinA Streptococcus pneumoniae TIGR4

93.301

100

0.933
  cinA Streptococcus pneumoniae Rx1

93.062

100

0.931
  cinA Streptococcus pneumoniae R6

93.062

100

0.931
  cinA Streptococcus pneumoniae D39

92.823

100

0.928
  cinA Streptococcus mutans UA159

71.77

100

0.718
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

100

0.459

Multiple sequence alignment