Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   SMI_RS09355 Genome accession   NC_013853
Coordinates   1906141..1906770 (-) Length   209 a.a.
NCBI ID   WP_000413915.1    Uniprot ID   D3HB34
Organism   Streptococcus mitis B6     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1901141..1911770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS09330 (smi_1839) recA 1901488..1902642 (-) 1155 WP_001085455.1 recombinase RecA Machinery gene
  SMI_RS09335 (smi_1840) cinA 1902697..1903953 (-) 1257 WP_000642685.1 competence/damage-inducible protein A Machinery gene
  SMI_RS09340 (smi_1841) brpA 1904031..1905086 (-) 1056 WP_000239268.1 biofilm formation/cell division transcriptional regulator BrpA -
  SMI_RS09345 (smi_1842) - 1905094..1905612 (-) 519 WP_000455529.1 GNAT family N-acetyltransferase -
  SMI_RS09350 (smi_1843) tsaE 1905602..1906045 (-) 444 WP_000288245.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  SMI_RS09355 (smi_1844) comM 1906141..1906770 (-) 630 WP_000413915.1 competence protein Regulator
  SMI_RS09360 (smi_1845) ndk 1906904..1907326 (-) 423 WP_000438298.1 nucleoside-diphosphate kinase -
  SMI_RS09365 (smi_1846) rpoC 1907434..1911111 (-) 3678 WP_000228743.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23932.07 Da        Isoelectric Point: 9.2987

>NTDB_id=36340 SMI_RS09355 WP_000413915.1 1906141..1906770(-) (comM) [Streptococcus mitis B6]
MEKMKKQIRILLLLTVFGISSCSCLSLSTWALMLNQNCFYYLVGMLLLASIGAGINYYSGQRNQSYSVFKEDKQQFLYSL
LLLVNILGLALIVIEHILAGNTSVEGFVEAFLPSFFFLFGIDLLVFLPIQKYVNGLKKILGKKEMCFISGLAILVFLRNP
WMLLSMTFYITLGMLFLGLLVPKVIRWEVSFYSHLMRDILLVVFLLFLF

Nucleotide


Download         Length: 630 bp        

>NTDB_id=36340 SMI_RS09355 WP_000413915.1 1906141..1906770(-) (comM) [Streptococcus mitis B6]
ATGGAAAAAATGAAAAAGCAAATTCGTATTTTGTTATTGCTGACAGTTTTTGGTATTAGTAGCTGTTCTTGTTTAAGTTT
ATCGACTTGGGCCTTGATGTTAAATCAAAACTGCTTCTATTATTTAGTTGGCATGTTGCTCCTTGCCAGTATTGGGGCAG
GGATAAACTACTATAGTGGACAGCGAAATCAATCTTATTCAGTTTTTAAGGAAGACAAGCAACAATTCTTGTATAGTCTG
TTGCTCTTAGTAAATATTTTGGGTTTAGCTTTAATTGTCATAGAACATATCCTTGCAGGAAATACATCTGTAGAAGGGTT
TGTGGAAGCCTTTCTACCGAGTTTCTTTTTCTTATTTGGTATTGATTTGCTAGTCTTTTTACCGATTCAGAAGTATGTAA
ATGGATTGAAAAAGATTTTGGGAAAGAAGGAGATGTGTTTTATTAGTGGACTAGCTATTCTAGTCTTTCTCAGAAATCCT
TGGATGCTATTATCTATGACATTTTATATTACCTTAGGAATGCTATTTCTAGGACTGTTGGTGCCAAAAGTCATTCGCTG
GGAAGTTTCATTTTACAGCCATTTGATGAGAGATATCTTGTTAGTTGTCTTCTTGCTGTTTCTATTTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3HB34

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus mitis SK321

95.477

95.215

0.909
  comM Streptococcus mitis NCTC 12261

94.472

95.215

0.9
  comM Streptococcus pneumoniae D39

40

98.086

0.392
  comM Streptococcus pneumoniae R6

40

98.086

0.392
  comM Streptococcus pneumoniae TIGR4

40

98.086

0.392

Multiple sequence alignment