Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   E4185_RS08610 Genome accession   NZ_CP038443
Coordinates   1800558..1801799 (-) Length   413 a.a.
NCBI ID   WP_043133310.1    Uniprot ID   -
Organism   Aeromonas media strain R1-18     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1795558..1806799
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4185_RS08585 (E4185_08650) mutT 1797528..1797932 (+) 405 WP_043133317.1 8-oxo-dGTP diphosphatase MutT -
  E4185_RS08590 (E4185_08655) yacG 1798008..1798202 (-) 195 WP_042649030.1 DNA gyrase inhibitor YacG -
  E4185_RS08595 (E4185_08660) zapD 1798212..1798934 (-) 723 WP_161507570.1 cell division protein ZapD -
  E4185_RS08600 (E4185_08665) coaE 1798972..1799586 (-) 615 WP_171273130.1 dephospho-CoA kinase -
  E4185_RS08605 (E4185_08670) pilD 1799605..1800477 (-) 873 WP_171273131.1 A24 family peptidase Machinery gene
  E4185_RS08610 (E4185_08675) pilC 1800558..1801799 (-) 1242 WP_043133310.1 type II secretion system F family protein Machinery gene
  E4185_RS08615 (E4185_08680) pilB 1801929..1803635 (-) 1707 WP_171273132.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  E4185_RS08620 (E4185_08685) - 1803639..1804061 (-) 423 WP_171274319.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  E4185_RS08625 (E4185_08695) nadC 1804386..1805249 (-) 864 WP_171273133.1 carboxylating nicotinate-nucleotide diphosphorylase -
  E4185_RS08630 (E4185_08700) - 1805253..1805723 (-) 471 WP_042648139.1 retropepsin-like aspartic protease -
  E4185_RS08635 (E4185_08705) ampD 1805860..1806432 (+) 573 WP_043128627.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45535.60 Da        Isoelectric Point: 10.1464

>NTDB_id=354362 E4185_RS08610 WP_043133310.1 1800558..1801799(-) (pilC) [Aeromonas media strain R1-18]
MATLAQKRNTPKKVFSFRWHGFNRKGQKVSGEFQADSINTVKAELRKQGVNVTKVSKQGQGLFSKGGARIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIATDVETGTPLSEALRRHPRHFDALYCDLVDAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPAMVILVAIIVTSILLLFVIPQFEEIFKSFGAELPVFTRFVIGISRFMQAWWYIIFGGTA
LAIFLYVRAWRKSQKVRDNTDRFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAILAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=354362 E4185_RS08610 WP_043133310.1 1800558..1801799(-) (pilC) [Aeromonas media strain R1-18]
ATGGCAACATTAGCGCAAAAACGTAACACACCTAAAAAGGTCTTCTCCTTCCGCTGGCATGGATTCAATCGCAAGGGACA
AAAGGTTTCCGGTGAGTTCCAGGCCGACAGCATCAACACCGTCAAGGCGGAGCTGCGCAAGCAGGGCGTCAATGTCACCA
AGGTCAGCAAGCAGGGCCAGGGCCTGTTTTCCAAGGGGGGTGCTCGGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCGGCCGGTGTGCCGCTGGTGCAAAGCTTGCAGATCATCGCCCGCGGTCATGAGAAGGCAGC
AGTACGCGAACTCATCGGCCAGATCGCCACCGATGTGGAAACCGGCACTCCGCTGTCAGAGGCGCTGCGCCGCCATCCCC
GCCACTTCGATGCGCTTTACTGCGACCTGGTAGACGCGGGGGAGCAGTCCGGCGCGCTGGAAACCATCTACGACCGGATT
GCCACATACCGCGAGAAGAGTGAGGCGCTGAAGTCCAAGATCAAGAAAGCCATGTTCTATCCCGCCATGGTCATCCTGGT
CGCCATCATCGTAACCTCCATCCTGCTGCTGTTCGTCATTCCCCAGTTCGAGGAGATTTTCAAGAGCTTCGGAGCAGAGC
TGCCAGTCTTCACCCGATTCGTCATCGGTATCTCCCGCTTCATGCAAGCTTGGTGGTATATCATCTTTGGTGGCACAGCC
TTGGCCATCTTCCTCTATGTGCGCGCCTGGCGAAAATCCCAGAAGGTACGGGACAACACGGACAGATTCATCCTCACCAT
TCCGGTCGTGGGCAACATATTGCACAAGGCGGCCATGGCCCGTTTCGCCCGTACCCTCTCCACCACCTTCTCCGCCGGGA
TACCTCTGGTGGATGCTCTGGTGTCAGCGGCCGGCGCCTCTGGCAACTATGTCTATCGCACGGCCATCCTGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCGATGCGCACAGTGGATCTCTTCCCAGACATGGTGATCCAGATGGT
GATGATTGGTGAAGAGTCAGGCGCCATCGATGACATGCTCTCCAAGGTTGCCGCCATCTTCGAGCAGGAGGTGGACGACA
TGGTCGATGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTTGGGGTGCTGGTCGGTGGCATGGTCGTCGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.818

95.884

0.545
  pilC Legionella pneumophila strain ERS1305867

53.086

98.063

0.521
  pilC Acinetobacter baumannii D1279779

51.122

97.094

0.496
  pilC Acinetobacter baylyi ADP1

50.63

96.126

0.487
  pilC Vibrio cholerae strain A1552

48

96.852

0.465
  pilC Vibrio campbellii strain DS40M4

46.482

96.368

0.448
  pilG Neisseria gonorrhoeae MS11

40.05

97.337

0.39
  pilG Neisseria meningitidis 44/76-A

39.801

97.337

0.387
  pilC Thermus thermophilus HB27

39

96.852

0.378

Multiple sequence alignment