Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   E4184_RS19745 Genome accession   NZ_CP038441
Coordinates   4267831..4269072 (+) Length   413 a.a.
NCBI ID   WP_106885656.1    Uniprot ID   A0AAP4J3C9
Organism   Aeromonas media strain T0.1-19     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4262831..4274072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4184_RS19720 (E4184_19875) ampD 4263182..4263754 (-) 573 WP_171276939.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  E4184_RS19725 (E4184_19880) - 4263891..4264361 (+) 471 WP_171276940.1 retropepsin-like aspartic protease -
  E4184_RS19730 (E4184_19885) nadC 4264365..4265228 (+) 864 WP_171276941.1 carboxylating nicotinate-nucleotide diphosphorylase -
  E4184_RS19735 (E4184_19895) - 4265541..4265990 (+) 450 WP_171276942.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  E4184_RS19740 (E4184_19900) pilB 4265994..4267700 (+) 1707 WP_171276943.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  E4184_RS19745 (E4184_19905) pilC 4267831..4269072 (+) 1242 WP_106885656.1 type II secretion system F family protein Machinery gene
  E4184_RS19750 (E4184_19910) pilD 4269153..4270025 (+) 873 WP_171276944.1 A24 family peptidase Machinery gene
  E4184_RS19755 (E4184_19915) coaE 4270044..4270658 (+) 615 WP_171276945.1 dephospho-CoA kinase -
  E4184_RS19760 (E4184_19920) zapD 4270696..4271418 (+) 723 WP_162520171.1 cell division protein ZapD -
  E4184_RS19765 (E4184_19925) yacG 4271428..4271622 (+) 195 WP_025328449.1 DNA gyrase inhibitor YacG -
  E4184_RS19770 (E4184_19930) mutT 4271697..4272101 (-) 405 WP_106885652.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45345.33 Da        Isoelectric Point: 9.9044

>NTDB_id=354339 E4184_RS19745 WP_106885656.1 4267831..4269072(+) (pilC) [Aeromonas media strain T0.1-19]
MATLAQKQNAPKKVFSFRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQGQGMFSKGGARIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSDALRRHPRHFDALYCDLVEAGEQSGALETIYDRI
AIYREKSEALKSKIKKAMFYPAMVILVAIIVTSILLLFVIPQFEEIFKSFGAELPAFTRFIIAISRFMQDWWYAIFGGIA
LTVFLYVRAWRSSQKVRDNTDKFILSIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATLAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=354339 E4184_RS19745 WP_106885656.1 4267831..4269072(+) (pilC) [Aeromonas media strain T0.1-19]
ATGGCAACATTAGCTCAAAAACAGAATGCACCAAAAAAGGTCTTCTCCTTCCGCTGGCACGGCGTCAATCGCAAGGGACA
AAAGGTTTCCGGTGAGCTGCAGGCCGACAGCATCACGACCGTCAAGGCGGAGCTGCGCAAGCAGGGCGTCAATGTCACCA
GGGTCAGCAAACAGGGTCAGGGGATGTTTTCCAAGGGCGGCGCCAGGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCCGCCGGTGTGCCGCTGGTGCAGAGCCTGCAGATCATCGCCCGCGGCCACGAAAAAGCGGC
GGTGCGCGAGCTGATCGGCCAGATCGCCGCCGATGTGGAGACAGGCACCCCACTGTCGGATGCGCTGCGCCGCCATCCCC
GCCATTTTGATGCCCTCTACTGTGATCTGGTGGAGGCGGGGGAGCAGTCCGGCGCGCTGGAAACCATCTACGACCGGATT
GCCATCTATCGCGAGAAGAGCGAGGCGCTCAAATCCAAAATAAAGAAGGCCATGTTCTATCCCGCCATGGTCATCCTGGT
CGCCATCATAGTGACCTCCATACTGTTGCTGTTCGTCATCCCCCAGTTCGAAGAGATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTCACCCGATTCATCATTGCCATCTCCCGCTTCATGCAGGATTGGTGGTACGCCATCTTCGGCGGCATAGCC
CTGACAGTATTCCTCTATGTGCGCGCCTGGCGCAGCTCTCAGAAGGTACGTGACAACACCGACAAGTTCATCCTCTCCAT
TCCGGTCGTTGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TTCCCCTGGTGGATGCCCTGGTCTCCGCTGCCGGGGCCTCGGGCAACTATGTCTATCGCACGGCTACCCTGGCCATTCGC
AACGAGGTTGTGGCAGGGATGCAGATCAACGTGGCGATGCGCACGGTCGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATAGGTGAAGAGTCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATCTTCGAGCAGGAGGTGGACGACA
TGGTCGATGGTCTCACCAGCCTGCTCGAGCCCATCATAATGGTGGTGCTGGGGGTGCTGGTCGGTGGCATGGTCGTCGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

55.303

95.884

0.53
  pilC Legionella pneumophila strain ERS1305867

51.605

98.063

0.506
  pilC Acinetobacter baumannii D1279779

51.87

97.094

0.504
  pilC Acinetobacter baylyi ADP1

50.882

96.126

0.489
  pilC Vibrio cholerae strain A1552

46.192

98.547

0.455
  pilC Vibrio campbellii strain DS40M4

44.802

97.821

0.438
  pilG Neisseria meningitidis 44/76-A

40.247

98.063

0.395
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilC Thermus thermophilus HB27

38

96.852

0.368

Multiple sequence alignment