Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbB/cilA   Type   Machinery gene
Locus tag   ES298_RS09075 Genome accession   NZ_CP038253
Coordinates   1778178..1778558 (-) Length   126 a.a.
NCBI ID   WP_033621334.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901929     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1776100..1837975 1778178..1778558 within 0


Gene organization within MGE regions


Location: 1776100..1837975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES298_RS09065 (ES298_09575) groL 1776100..1777722 (-) 1623 WP_000031573.1 chaperonin GroEL -
  ES298_RS09070 (ES298_09580) groES 1777738..1778022 (-) 285 WP_000917299.1 co-chaperone GroES -
  ES298_RS09075 (ES298_09585) ssbB/cilA 1778178..1778558 (-) 381 WP_033621334.1 single-stranded DNA-binding protein Machinery gene
  ES298_RS09080 (ES298_09590) - 1778582..1778824 (-) 243 WP_000698517.1 hypothetical protein -
  ES298_RS09085 (ES298_09595) lytA 1779056..1780012 (-) 957 WP_000350534.1 N-acetylmuramoyl-L-alanine amidase LytA -
  ES298_RS09090 (ES298_09600) - 1780018..1780347 (-) 330 WP_001186214.1 phage holin -
  ES298_RS09095 (ES298_09605) - 1780351..1780650 (-) 300 WP_001810279.1 hypothetical protein -
  ES298_RS09100 (ES298_09610) - 1780660..1781010 (-) 351 WP_054393306.1 hypothetical protein -
  ES298_RS09105 (ES298_09615) - 1781013..1781216 (-) 204 WP_001091110.1 hypothetical protein -
  ES298_RS11325 (ES298_09620) - 1781197..1781313 (-) 117 WP_001063633.1 hypothetical protein -
  ES298_RS09110 - 1781310..1788848 (-) 7539 WP_409202203.1 tail fiber domain-containing protein -
  ES298_RS09115 (ES298_09635) - 1788889..1789239 (-) 351 WP_000068023.1 DUF6711 family protein -
  ES298_RS09120 (ES298_09640) - 1789248..1792862 (-) 3615 WP_061642927.1 hypothetical protein -
  ES298_RS09125 (ES298_09645) - 1792849..1793199 (-) 351 WP_000478007.1 hypothetical protein -
  ES298_RS09130 (ES298_09650) - 1793238..1793618 (-) 381 WP_001185631.1 DUF6096 family protein -
  ES298_RS09135 (ES298_09655) - 1793623..1794036 (-) 414 WP_000880665.1 phage tail tube protein -
  ES298_RS09140 (ES298_09660) - 1794039..1794407 (-) 369 WP_000608235.1 hypothetical protein -
  ES298_RS09145 (ES298_09665) - 1794404..1794919 (-) 516 WP_000015940.1 HK97-gp10 family putative phage morphogenesis protein -
  ES298_RS09150 (ES298_09670) - 1794894..1795232 (-) 339 WP_000478943.1 hypothetical protein -
  ES298_RS09155 (ES298_09675) - 1795213..1795524 (-) 312 WP_000021218.1 phage head-tail connector protein -
  ES298_RS09160 (ES298_09680) - 1795526..1795714 (-) 189 WP_000669348.1 hypothetical protein -
  ES298_RS09165 (ES298_09685) - 1795724..1796749 (-) 1026 WP_000863393.1 carbohydrate-binding protein -
  ES298_RS09170 (ES298_09690) - 1796772..1797296 (-) 525 WP_001288018.1 DUF4355 domain-containing protein -
  ES298_RS09175 - 1797563..1797736 (-) 174 WP_000356388.1 hypothetical protein -
  ES298_RS09180 (ES298_09695) - 1797778..1798191 (-) 414 WP_000565273.1 HD domain-containing protein -
  ES298_RS09185 (ES298_09700) - 1798188..1798397 (-) 210 WP_000651747.1 hypothetical protein -
  ES298_RS09190 (ES298_09705) - 1798399..1800036 (-) 1638 WP_178387375.1 minor capsid protein -
  ES298_RS09195 (ES298_09710) - 1799945..1801414 (-) 1470 WP_075275088.1 phage portal protein -
  ES298_RS09200 (ES298_09715) - 1801426..1802724 (-) 1299 WP_061389546.1 PBSX family phage terminase large subunit -
  ES298_RS09205 (ES298_09720) - 1802702..1803202 (-) 501 WP_001155235.1 terminase small subunit -
  ES298_RS09215 (ES298_09725) - 1803610..1804014 (-) 405 WP_001030241.1 DUF1492 domain-containing protein -
  ES298_RS09220 (ES298_09730) - 1804087..1804458 (-) 372 WP_001247150.1 hypothetical protein -
  ES298_RS09225 (ES298_09735) - 1804455..1804892 (-) 438 WP_000188937.1 YopX family protein -
  ES298_RS09230 (ES298_09740) - 1804904..1805326 (-) 423 WP_000140868.1 hypothetical protein -
  ES298_RS09235 (ES298_09745) - 1805323..1805583 (-) 261 WP_000819329.1 DUF1372 family protein -
  ES298_RS11210 - 1805580..1805702 (-) 123 WP_001842508.1 hypothetical protein -
  ES298_RS09240 (ES298_09750) - 1805741..1806229 (-) 489 WP_001041151.1 DUF1642 domain-containing protein -
  ES298_RS09245 (ES298_09755) - 1806231..1806548 (-) 318 WP_000969676.1 hypothetical protein -
  ES298_RS09250 (ES298_09760) - 1806573..1806755 (-) 183 WP_000796349.1 hypothetical protein -
  ES298_RS09255 (ES298_09765) - 1806771..1807202 (-) 432 WP_000779141.1 RusA family crossover junction endodeoxyribonuclease -
  ES298_RS09260 (ES298_09770) - 1807199..1807528 (-) 330 WP_000157070.1 hypothetical protein -
  ES298_RS09265 (ES298_09775) - 1807542..1807751 (-) 210 WP_000455270.1 hypothetical protein -
  ES298_RS09270 (ES298_09780) - 1807753..1808448 (-) 696 WP_000401828.1 site-specific DNA-methyltransferase -
  ES298_RS09275 (ES298_09785) ssbA 1808461..1808877 (-) 417 WP_000609559.1 single-stranded DNA-binding protein Machinery gene
  ES298_RS09280 (ES298_09790) - 1808972..1809307 (-) 336 WP_000598345.1 sporulation protein Cse60 -
  ES298_RS09285 (ES298_09795) - 1809300..1809623 (-) 324 WP_000354630.1 hypothetical protein -
  ES298_RS09290 (ES298_09800) - 1809601..1810689 (-) 1089 WP_001157029.1 DUF1351 domain-containing protein -
  ES298_RS09295 (ES298_09805) bet 1810699..1811517 (-) 819 WP_000184004.1 phage recombination protein Bet -
  ES298_RS09300 (ES298_09810) - 1811787..1812047 (-) 261 WP_000471459.1 hypothetical protein -
  ES298_RS09305 (ES298_09815) - 1812060..1812314 (-) 255 WP_000275523.1 hypothetical protein -
  ES298_RS09310 (ES298_09820) - 1812315..1812536 (-) 222 WP_000771950.1 hypothetical protein -
  ES298_RS09315 - 1812536..1812673 (-) 138 WP_000869368.1 hypothetical protein -
  ES298_RS09320 (ES298_09825) - 1812691..1813488 (-) 798 WP_001056933.1 ParB N-terminal domain-containing protein -
  ES298_RS09325 - 1813555..1813698 (-) 144 WP_000389589.1 hypothetical protein -
  ES298_RS09330 (ES298_09830) - 1813817..1814008 (+) 192 WP_000834563.1 hypothetical protein -
  ES298_RS09335 (ES298_09840) - 1814418..1814738 (-) 321 WP_223687705.1 HTH domain-containing protein -
  ES298_RS09340 (ES298_09845) - 1814823..1815050 (-) 228 WP_001125554.1 helix-turn-helix transcriptional regulator -
  ES298_RS09345 (ES298_09850) - 1815123..1815329 (+) 207 WP_000133214.1 hypothetical protein -
  ES298_RS09350 - 1815554..1815724 (-) 171 WP_000660185.1 hypothetical protein -
  ES298_RS09355 (ES298_09860) - 1815923..1816372 (+) 450 WP_001058908.1 hypothetical protein -
  ES298_RS09360 - 1816363..1816530 (-) 168 WP_001005822.1 hypothetical protein -
  ES298_RS09365 (ES298_09865) - 1816605..1816880 (-) 276 WP_001094375.1 hypothetical protein -
  ES298_RS09370 (ES298_09870) - 1817053..1817844 (+) 792 WP_000090699.1 XRE family transcriptional regulator -
  ES298_RS09375 (ES298_09875) - 1817846..1818046 (+) 201 WP_000064302.1 hypothetical protein -
  ES298_RS09380 (ES298_09880) - 1818214..1819641 (+) 1428 WP_000859012.1 recombinase family protein -
  ES298_RS09385 (ES298_09885) - 1819777..1820538 (-) 762 WP_001107758.1 SDR family NAD(P)-dependent oxidoreductase -
  ES298_RS09390 (ES298_09890) ytpR 1820580..1821206 (-) 627 WP_000578289.1 YtpR family tRNA-binding protein -
  ES298_RS09395 (ES298_09895) - 1821222..1821539 (-) 318 WP_000615769.1 thioredoxin family protein -
  ES298_RS09400 (ES298_09900) - 1821536..1821835 (-) 300 WP_001013974.1 DUF4651 domain-containing protein -
  ES298_RS09405 - 1822033..1822095 (-) 63 WP_219335288.1 hypothetical protein -
  ES298_RS09410 (ES298_09910) - 1822120..1822311 (-) 192 WP_000291826.1 cell wall-binding protein -
  ES298_RS09415 (ES298_09915) - 1822472..1823146 (-) 675 WP_000725750.1 LiaF transmembrane domain-containing protein -
  ES298_RS09420 (ES298_09920) - 1823152..1823598 (-) 447 WP_000776589.1 LytTR family DNA-binding domain-containing protein -
  ES298_RS09425 (ES298_09925) - 1823712..1824215 (-) 504 WP_000800942.1 phosphatase PAP2 family protein -
  ES298_RS09430 (ES298_09930) - 1824212..1824574 (-) 363 WP_000078805.1 DUF2200 domain-containing protein -
  ES298_RS09435 rcrQ 1824640..1825671 (-) 1032 WP_000506424.1 ABC transporter ATP-binding protein Regulator
  ES298_RS09440 rcrP 1825678..1826499 (-) 822 WP_000601682.1 ABC transporter permease Regulator
  ES298_RS09445 (ES298_09940) - 1826515..1826985 (-) 471 WP_000517879.1 MarR family winged helix-turn-helix transcriptional regulator -
  ES298_RS09450 (ES298_09950) - 1827109..1827825 (-) 717 WP_000532876.1 YebC/PmpR family DNA-binding transcriptional regulator -
  ES298_RS09455 (ES298_09960) ply 1828706..1830121 (-) 1416 WP_001284363.1 cholesterol-dependent cytolysin pneumolysin -
  ES298_RS09460 (ES298_09965) - 1830132..1830542 (-) 411 WP_000595757.1 hypothetical protein -
  ES298_RS09465 (ES298_09970) - 1830535..1831143 (-) 609 WP_000083614.1 hypothetical protein -
  ES298_RS09470 (ES298_09975) - 1831156..1831614 (-) 459 WP_000186955.1 DUF4231 domain-containing protein -
  ES298_RS09475 (ES298_09980) - 1831848..1832138 (+) 291 Protein_1877 transposase family protein -
  ES298_RS09480 (ES298_09985) - 1832640..1833500 (+) 861 WP_001810270.1 glycerophosphodiester phosphodiesterase family protein -
  ES298_RS09485 (ES298_09990) - 1833484..1834545 (+) 1062 WP_000475761.1 extracellular solute-binding protein -
  ES298_RS09490 (ES298_09995) - 1834562..1835566 (+) 1005 WP_000627599.1 ABC transporter ATP-binding protein -
  ES298_RS09495 (ES298_10000) - 1835578..1837272 (+) 1695 WP_001232286.1 iron ABC transporter permease -
  ES298_RS09500 (ES298_10005) - 1837274..1837975 (+) 702 WP_001054457.1 MgtC/SapB family protein -

Sequence


Protein


Download         Length: 126 a.a.        Molecular weight: 14318.16 Da        Isoelectric Point: 5.2813

>NTDB_id=352719 ES298_RS09075 WP_033621334.1 1778178..1778558(-) (ssbB/cilA) [Streptococcus pneumoniae strain TVO_1901929]
MLIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKN
GQMNYVTEVLVTGFQLLESRAQRAMRENNAGQDLADLVLEEEELPF

Nucleotide


Download         Length: 381 bp        

>NTDB_id=352719 ES298_RS09075 WP_033621334.1 1778178..1778558(-) (ssbB/cilA) [Streptococcus pneumoniae strain TVO_1901929]
ATCTTGATTGGACGTTTAACGTCTACACCAGAATTGCACAAAACCAACAATGACAAGTCAGTAGCGCGAGCAACTATCGC
TGTCAACCGTCGTTACAAAGACCAAAACGGTGAACGTGAAGTTGATTTTGTCAATATGGTCCTATGGGGCAGACTAGCAG
AAACTTTGGCAAGCTACGCAACCAAAGGTAGTCTCATTTCCGTTGATGGAGAATTGCGTACCCGTCGCTTTGAGAAAAAT
GGTCAGATGAATTATGTAACCGAAGTCCTTGTGACAGGATTCCAACTCTTGGAAAGTCGTGCCCAACGTGCTATGCGTGA
AAATAATGCAGGCCAAGATTTGGCAGATTTGGTCTTGGAAGAGGAAGAATTGCCATTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbB/cilA Streptococcus pneumoniae TIGR4

98.413

100

0.984

  ssbB/cilA Streptococcus pneumoniae Rx1

97.619

100

0.976

  ssbB/cilA Streptococcus pneumoniae D39

97.619

100

0.976

  ssbB/cilA Streptococcus pneumoniae R6

97.619

100

0.976

  ssbB/cilA Streptococcus mitis SK321

97.619

100

0.976

  ssbB/cilA Streptococcus mitis NCTC 12261

96.032

100

0.96

  ssbA Streptococcus mutans UA159

73.016

100

0.73

  ssbB Streptococcus sobrinus strain NIDR 6715-7

68.254

100

0.683

  ssbB Lactococcus lactis subsp. cremoris KW2

60.55

86.508

0.524

  ssbA Bacillus subtilis subsp. subtilis str. 168

50.495

80.159

0.405

  ssb Latilactobacillus sakei subsp. sakei 23K

46.296

85.714

0.397


Multiple sequence alignment