Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   EZY40_RS00600 Genome accession   NZ_CP036530
Coordinates   97730..98056 (+) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain STAB09023     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 92730..103056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZY40_RS00585 (EZY40_00590) - 95362..95727 (+) 366 WP_002986560.1 DUF1033 family protein -
  EZY40_RS00590 (EZY40_00595) comYA 95820..96758 (+) 939 WP_020904831.1 competence type IV pilus ATPase ComGA Machinery gene
  EZY40_RS00595 (EZY40_00600) comYB 96694..97728 (+) 1035 WP_226316548.1 competence type IV pilus assembly protein ComGB Machinery gene
  EZY40_RS00600 (EZY40_00605) comYC 97730..98056 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  EZY40_RS00605 (EZY40_00610) comGD 98031..98459 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  EZY40_RS00610 (EZY40_00615) comGE 98416..98700 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  EZY40_RS00615 (EZY40_00620) comYF 98693..99127 (+) 435 WP_020904833.1 competence type IV pilus minor pilin ComGF Machinery gene
  EZY40_RS00620 (EZY40_00625) comGG 99111..99437 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  EZY40_RS00625 (EZY40_00630) comYH 99535..100488 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  EZY40_RS00630 (EZY40_00635) - 100547..101743 (+) 1197 WP_020904834.1 acetate kinase -
  EZY40_RS00635 (EZY40_00640) - 101930..102238 (+) 309 Protein_89 hypothetical protein -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=349390 EZY40_RS00600 WP_002986552.1 97730..98056(+) (comYC) [Streptococcus pyogenes strain STAB09023]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=349390 EZY40_RS00600 WP_002986552.1 97730..98056(+) (comYC) [Streptococcus pyogenes strain STAB09023]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546

  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537

  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528

  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519

  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519

  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519

  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519

  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519

  comYC Streptococcus mutans UA140

55.208

88.889

0.491

  comYC Streptococcus mutans UA159

55.208

88.889

0.491

  comYC Streptococcus suis isolate S10

59.259

75

0.444


Multiple sequence alignment