Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   M013TW_RS07700 Genome accession   NC_016928
Coordinates   1578188..1578895 (+) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus subsp. aureus M013     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1573188..1583895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M013TW_RS07630 (M013TW_1486) - 1573491..1573751 (-) 261 WP_001556704.1 DUF1108 family protein -
  M013TW_RS07635 (M013TW_1487) - 1573756..1574073 (-) 318 WP_000829610.1 hypothetical protein -
  M013TW_RS07640 (M013TW_03405) - 1574162..1574323 (-) 162 WP_001285954.1 DUF1270 domain-containing protein -
  M013TW_RS07645 (M013TW_1488) - 1574335..1574598 (-) 264 WP_001124198.1 helix-turn-helix domain-containing protein -
  M013TW_RS14240 - 1574748..1574846 (-) 99 Protein_1477 hypothetical protein -
  M013TW_RS07655 (M013TW_03415) - 1574843..1575121 (-) 279 WP_001206962.1 hypothetical protein -
  M013TW_RS14245 - 1575223..1575378 (+) 156 Protein_1479 hypothetical protein -
  M013TW_RS07660 (M013TW_1489) - 1575402..1575662 (-) 261 WP_000435343.1 hypothetical protein -
  M013TW_RS07665 (M013TW_1490) - 1575675..1576427 (-) 753 WP_001148617.1 phage antirepressor KilAC domain-containing protein -
  M013TW_RS07670 (M013TW_1491) - 1576488..1576715 (+) 228 WP_000801108.1 hypothetical protein -
  M013TW_RS07675 (M013TW_1492) - 1576717..1576908 (-) 192 WP_000502678.1 hypothetical protein -
  M013TW_RS07680 (M013TW_1493) - 1576965..1577174 (+) 210 WP_000772137.1 hypothetical protein -
  M013TW_RS07685 (M013TW_03420) - 1577167..1577307 (-) 141 WP_000939495.1 hypothetical protein -
  M013TW_RS07690 (M013TW_1494) - 1577322..1577765 (-) 444 WP_000435346.1 hypothetical protein -
  M013TW_RS07695 (M013TW_1495) - 1577778..1578017 (-) 240 WP_000548578.1 helix-turn-helix transcriptional regulator -
  M013TW_RS07700 (M013TW_1496) irvR 1578188..1578895 (+) 708 WP_000094093.1 XRE family transcriptional regulator Regulator
  M013TW_RS14180 - 1578907..1579062 (+) 156 WP_001049399.1 hypothetical protein -
  M013TW_RS07705 (M013TW_1498) - 1579049..1579234 (+) 186 WP_001089804.1 hypothetical protein -
  M013TW_RS07710 (M013TW_1499) - 1579434..1579616 (+) 183 WP_000705240.1 hypothetical protein -
  M013TW_RS07715 (M013TW_1500) - 1579652..1579798 (+) 147 WP_001013104.1 hypothetical protein -
  M013TW_RS07720 (M013TW_1501) - 1579795..1580409 (-) 615 WP_000191466.1 hypothetical protein -
  M013TW_RS07725 (M013TW_1502) - 1580535..1581740 (+) 1206 WP_000264751.1 site-specific integrase -
  M013TW_RS07730 (M013TW_1503) - 1581783..1583809 (-) 2027 Protein_1495 hypothetical protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=34773 M013TW_RS07700 WP_000094093.1 1578188..1578895(+) (irvR) [Staphylococcus aureus subsp. aureus M013]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=34773 M013TW_RS07700 WP_000094093.1 1578188..1578895(+) (irvR) [Staphylococcus aureus subsp. aureus M013]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374

Multiple sequence alignment