Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   EWG56_RS14640 Genome accession   NZ_CP035671
Coordinates   2833530..2833841 (+) Length   103 a.a.
NCBI ID   WP_000472256.1    Uniprot ID   -
Organism   Staphylococcus aureus strain VB31683     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2828530..2838841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EWG56_RS14610 (EWG56_14610) - 2829314..2829517 (+) 204 WP_000087561.1 YqgQ family protein -
  EWG56_RS14615 (EWG56_14615) - 2829514..2830500 (+) 987 WP_000161315.1 ROK family glucokinase -
  EWG56_RS14620 (EWG56_14620) - 2830500..2830829 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  EWG56_RS14625 (EWG56_14625) - 2830826..2831449 (+) 624 WP_001223006.1 MBL fold metallo-hydrolase -
  EWG56_RS14630 (EWG56_14630) comGA 2831500..2832474 (+) 975 WP_000697215.1 competence type IV pilus ATPase ComGA Machinery gene
  EWG56_RS14635 (EWG56_14635) comGB 2832446..2833516 (+) 1071 WP_000776403.1 competence type IV pilus assembly protein ComGB Machinery gene
  EWG56_RS14640 (EWG56_14640) comGC 2833530..2833841 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  EWG56_RS14645 (EWG56_14645) comGD 2833819..2834265 (+) 447 WP_075583651.1 competence type IV pilus minor pilin ComGD Machinery gene
  EWG56_RS14650 (EWG56_14650) comGE 2834252..2834551 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  EWG56_RS14655 (EWG56_14655) comGF 2834469..2834966 (+) 498 WP_029697681.1 competence type IV pilus minor pilin ComGF Machinery gene
  EWG56_RS14660 (EWG56_14660) - 2835063..2835209 (+) 147 WP_001789879.1 hypothetical protein -
  EWG56_RS14665 (EWG56_14665) - 2835199..2835723 (+) 525 WP_001015122.1 shikimate kinase -
  EWG56_RS14670 (EWG56_14670) gcvT 2835882..2836973 (+) 1092 WP_000093355.1 glycine cleavage system aminomethyltransferase GcvT -
  EWG56_RS14675 (EWG56_14675) gcvPA 2836993..2838339 (+) 1347 WP_000019688.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence


Protein


Download         Length: 103 a.a.        Molecular weight: 11315.36 Da        Isoelectric Point: 8.5268

>NTDB_id=343499 EWG56_RS14640 WP_000472256.1 2833530..2833841(+) (comGC) [Staphylococcus aureus strain VB31683]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=343499 EWG56_RS14640 WP_000472256.1 2833530..2833841(+) (comGC) [Staphylococcus aureus strain VB31683]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

100

100

1

  comGC Staphylococcus aureus N315

100

100

1

  comGC/cglC Streptococcus pneumoniae TIGR4

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae Rx1

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae D39

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae R6

46.078

99.029

0.456

  comGC/cglC Streptococcus mitis SK321

51.163

83.495

0.427

  comGC/cglC Streptococcus mitis NCTC 12261

51.163

83.495

0.427

  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408

  comYC Streptococcus suis isolate S10

50

75.728

0.379

  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369

  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369


Multiple sequence alignment