Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   ETT59_RS00675 Genome accession   NZ_CP035440
Coordinates   103545..103871 (+) Length   108 a.a.
NCBI ID   WP_136276522.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm124     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98545..108871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT59_RS00660 (ETT59_00660) - 101177..101542 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT59_RS00665 (ETT59_00665) comYA 101635..102573 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT59_RS00670 (ETT59_00670) comYB 102509..103543 (+) 1035 WP_227878117.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT59_RS00675 (ETT59_00675) comYC 103545..103871 (+) 327 WP_136276522.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT59_RS00680 (ETT59_00680) comGD 103846..104274 (+) 429 WP_136276529.1 competence type IV pilus minor pilin ComGD -
  ETT59_RS00685 (ETT59_00685) comGE 104231..104515 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  ETT59_RS00690 (ETT59_00690) comYF 104508..104942 (+) 435 WP_111711329.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT59_RS00695 (ETT59_00695) comGG 104926..105252 (+) 327 WP_136276521.1 competence type IV pilus minor pilin ComGG -
  ETT59_RS00700 (ETT59_00700) comYH 105350..106303 (+) 954 WP_009880357.1 class I SAM-dependent methyltransferase Machinery gene
  ETT59_RS00705 (ETT59_00705) - 106362..107558 (+) 1197 WP_010921803.1 acetate kinase -
  ETT59_RS00710 (ETT59_00710) - 107745..108053 (+) 309 WP_011284425.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12333.34 Da        Isoelectric Point: 9.6764

>NTDB_id=341676 ETT59_RS00675 WP_136276522.1 103545..103871(+) (comYC) [Streptococcus pyogenes strain emm124]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKALLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=341676 ETT59_RS00675 WP_136276522.1 103545..103871(+) (comYC) [Streptococcus pyogenes strain emm124]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGTTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCTTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

59.794

89.815

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment