Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   F6P95_RS02165 Genome accession   NZ_CP044293
Coordinates   419143..420975 (-) Length   610 a.a.
NCBI ID   WP_157716824.1    Uniprot ID   -
Organism   Escherichia coli strain P276M     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 414143..425975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6P95_RS02120 (F6P95_02135) yecR 414491..414814 (+) 324 WP_001237869.1 YecR-like lipofamily protein -
  F6P95_RS02125 (F6P95_02140) ftnA 414985..415482 (+) 498 WP_000917208.1 non-heme ferritin -
  F6P95_RS02130 (F6P95_02145) yecH 415520..415759 (-) 240 WP_000377225.1 YecH family metal-binding protein -
  F6P95_RS02135 (F6P95_02150) tyrP 415950..417161 (+) 1212 WP_157716823.1 tyrosine transporter TyrP -
  F6P95_RS02140 (F6P95_02155) yecA 417223..417888 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  F6P95_RS02160 (F6P95_02175) pgsA 418538..419086 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  F6P95_RS02165 (F6P95_02180) uvrC 419143..420975 (-) 1833 WP_157716824.1 excinuclease ABC subunit UvrC Machinery gene
  F6P95_RS02170 (F6P95_02185) letA 420972..421628 (-) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  F6P95_RS23300 (F6P95_02190) - 421770..421886 (+) 117 WP_001302039.1 hypothetical protein -
  F6P95_RS02175 (F6P95_02195) yecU 421924..422100 (+) 177 WP_001302050.1 protein YecU -
  F6P95_RS02180 (F6P95_02200) yecF 422087..422311 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  F6P95_RS02185 (F6P95_02205) sdiA 422379..423101 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  F6P95_RS02190 (F6P95_02210) tcyN 423331..424083 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  F6P95_RS02195 (F6P95_02215) tcyL 424080..424748 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  F6P95_RS02200 (F6P95_02220) dcyD 424763..425749 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68134.98 Da        Isoelectric Point: 9.1942

>NTDB_id=341675 F6P95_RS02165 WP_157716824.1 419143..420975(-) (uvrC) [Escherichia coli strain P276M]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRCVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=341675 F6P95_RS02165 WP_157716824.1 419143..420975(-) (uvrC) [Escherichia coli strain P276M]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGCAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCACACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATATTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGT
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTGATTAGCCGTA
TGGAAACTGCCAGCCAGAATTTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGATGCGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGCCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCACTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACACTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGCTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-236)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

Helix-hairpin-helix domain (HHH_5)

(558-609)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374

Multiple sequence alignment