Detailed information NTG0337150

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EQH38_RS07235
• Genome accession: NZ_CP035242
• Coordinates: 1397379..1399616 (-)
• Length: 745 a.a.
• NCBI ID: WP_238097306.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901947
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1392379..1404616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH38_RS07200 (EQH38_07590)	-	1393289..1393669 (-)	381	WP_054366114.1	VOC family protein	-
EQH38_RS07205 (EQH38_07595)	rplT	1393727..1394086 (-)	360	WP_000124836.1	50S ribosomal protein L20	-
EQH38_RS07210 (EQH38_07600)	rpmI	1394138..1394338 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
EQH38_RS07215 (EQH38_07605)	infC	1394371..1394901 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
EQH38_RS07220 (EQH38_07610)	-	1395208..1396389 (-)	1182	WP_000655951.1	membrane protein	-
EQH38_RS07225 (EQH38_07615)	-	1396393..1396980 (-)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
EQH38_RS07230 (EQH38_07620)	-	1397012..1397200 (-)	189	WP_001809102.1	hypothetical protein	-
EQH38_RS07235 (EQH38_07625)	comEC/celB	1397379..1399616 (-)	2238	WP_238097306.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH38_RS07240 (EQH38_07630)	comEA/celA/cilE	1399600..1400250 (-)	651	WP_000387336.1	ComEA family DNA-binding protein	Machinery gene
EQH38_RS07245 (EQH38_07635)	-	1400318..1400887 (-)	570	WP_000443749.1	GNAT family N-acetyltransferase	-
EQH38_RS07250 (EQH38_07640)	ald	1401064..1402174 (+)	1111	Protein_1412	alanine dehydrogenase	-
EQH38_RS07255 (EQH38_07645)	-	1402428..1402802 (-)	375	Protein_1413	TfoX/Sxy family protein	-
EQH38_RS07260 (EQH38_07650)	-	1402805..1403305 (-)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EQH38_RS07265 (EQH38_07660)	-	1403498..1404466 (-)	969	WP_000658191.1	PhoH family protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84392.82 Da
• Isoelectric Point: 9.5761

>NTDB_id=337150 EQH38_RS07235 WP_238097306.1 1397379..1399616(-) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901947]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPSLGQPNEWLLILLLISLPLVYDLRKNIKGLTVLSLLITGLFFLTKH
PLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKE
HVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKFL
DKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINS
KVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2238 bp

>NTDB_id=337150 EQH38_RS07235 WP_238097306.1 1397379..1399616(-) (comEC/celB) [Streptococcus pneumoniae strain TVO_1901947]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACAGTGTTTCTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
CTCACAGGTGGCAAGTAGGCCTAGTCTTGGACAACCCAATGAATGGCTTTTAATCCTATTGTTAATTTCTTTGCCTTTGG
TCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAGCAT
CCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAACCAT
TCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATGCCC
AGCGAACCTTGATTCCCTATCTCAAAAGTCGGGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAGGAG
CATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACAGAA
GGAATTTGTGGCAGAATTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTGGAA
GTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTCTTG
GATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAAAGT
AAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGCTTA
CTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAATAGC
AAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-692)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (216-456)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	98.391	100	0.985
comEC/celB	Streptococcus pneumoniae Rx1	97.453	100	0.976
comEC/celB	Streptococcus pneumoniae D39	97.453	100	0.976
comEC/celB	Streptococcus pneumoniae R6	97.453	100	0.976
comEC/celB	Streptococcus mitis SK321	91.421	100	0.915
comEC/celB	Streptococcus mitis NCTC 12261	91.275	100	0.913
comEC	Lactococcus lactis subsp. cremoris KW2	44.13	99.463	0.439