Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   EG363_RS05370 Genome accession   NZ_CP033865
Coordinates   1073122..1073433 (-) Length   103 a.a.
NCBI ID   WP_000472257.1    Uniprot ID   A0A115HMG3
Organism   Staphylococcus aureus strain FDAARGOS_504     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1068122..1078433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EG363_RS05335 (EG363_05340) gcvPA 1068624..1069970 (-) 1347 WP_000019697.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  EG363_RS05340 (EG363_05345) gcvT 1069990..1071081 (-) 1092 WP_000093347.1 glycine cleavage system aminomethyltransferase GcvT -
  EG363_RS05345 (EG363_05350) - 1071240..1071764 (-) 525 WP_001015125.1 shikimate kinase -
  EG363_RS05350 (EG363_05355) - 1071754..1071900 (-) 147 WP_001789879.1 hypothetical protein -
  EG363_RS05355 (EG363_05360) comGF 1071997..1072494 (-) 498 WP_001794328.1 competence type IV pilus minor pilin ComGF Machinery gene
  EG363_RS05360 (EG363_05365) comGE 1072412..1072711 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  EG363_RS05365 (EG363_05370) comGD 1072698..1073144 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  EG363_RS05370 (EG363_05375) comGC 1073122..1073433 (-) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  EG363_RS05375 (EG363_05380) comGB 1073447..1074517 (-) 1071 WP_000776412.1 competence type IV pilus assembly protein ComGB Machinery gene
  EG363_RS05380 (EG363_05385) comGA 1074489..1075463 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  EG363_RS05385 (EG363_05390) - 1075515..1076138 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  EG363_RS05390 (EG363_05395) - 1076135..1076464 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  EG363_RS05395 (EG363_05400) - 1076464..1077450 (-) 987 WP_000161314.1 ROK family glucokinase -
  EG363_RS05400 (EG363_05405) - 1077447..1077650 (-) 204 WP_000087561.1 YqgQ family protein -

Sequence

Protein


Download         Length: 103 a.a.        Molecular weight: 11373.39 Da        Isoelectric Point: 7.8600

>NTDB_id=326556 EG363_RS05370 WP_000472257.1 1073122..1073433(-) (comGC) [Staphylococcus aureus strain FDAARGOS_504]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEEQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=326556 EG363_RS05370 WP_000472257.1 1073122..1073433(-) (comGC) [Staphylococcus aureus strain FDAARGOS_504]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGAGCAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(6-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A115HMG3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

99.029

100

0.99
  comGC Staphylococcus aureus MW2

99.029

100

0.99
  comGC/cglC Streptococcus mitis SK321

48.039

99.029

0.476
  comGC/cglC Streptococcus pneumoniae R6

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae D39

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae TIGR4

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae Rx1

47.059

99.029

0.466
  comGC/cglC Streptococcus mitis NCTC 12261

52.326

83.495

0.437
  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408
  comYC Streptococcus suis isolate S10

50

75.728

0.379
  comYC Streptococcus mutans UA140

50

73.786

0.369
  comYC Streptococcus mutans UA159

50

73.786

0.369
  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369
  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369

Multiple sequence alignment