Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   EB818_RS00670 Genome accession   NZ_CP033335
Coordinates   103931..104257 (+) Length   108 a.a.
NCBI ID   WP_011528161.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY208     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98931..109257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB818_RS00655 (EB818_00655) - 101563..101928 (+) 366 WP_002986560.1 DUF1033 family protein -
  EB818_RS00660 (EB818_00660) comYA 102021..102959 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  EB818_RS00665 (EB818_00665) comYB 102895..103929 (+) 1035 WP_228631569.1 competence type IV pilus assembly protein ComGB Machinery gene
  EB818_RS00670 (EB818_00670) comYC 103931..104257 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  EB818_RS00675 (EB818_00675) comGD 104232..104660 (+) 429 WP_076639399.1 competence type IV pilus minor pilin ComGD -
  EB818_RS00680 (EB818_00680) comGE 104617..104901 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  EB818_RS00685 (EB818_00685) comYF 104894..105328 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EB818_RS00690 (EB818_00690) comGG 105312..105638 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  EB818_RS00695 (EB818_00695) comYH 105736..106689 (+) 954 WP_129322573.1 class I SAM-dependent methyltransferase Machinery gene
  EB818_RS00700 (EB818_00700) - 106748..107944 (+) 1197 WP_020904834.1 acetate kinase -
  EB818_RS00705 (EB818_00705) - 108131..108439 (+) 309 Protein_88 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12362.29 Da        Isoelectric Point: 9.6949

>NTDB_id=322997 EB818_RS00670 WP_011528161.1 103931..104257(+) (comYC) [Streptococcus pyogenes strain TSPY208]
MINQWNNLRHKNLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=322997 EB818_RS00670 WP_011528161.1 103931..104257(+) (comYC) [Streptococcus pyogenes strain TSPY208]
ATGATTAATCAATGGAACAACTTACGACACAAGAATCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
TATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis SK321

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus mitis NCTC 12261

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comYC Streptococcus mutans UA159

52.475

93.519

0.491
  comYC Streptococcus mutans UA140

52.475

93.519

0.491
  comYC Streptococcus suis isolate S10

58.025

75

0.435

Multiple sequence alignment